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Cataract clinical trials

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NCT ID: NCT03506542 Completed - Cataract Clinical Trials

Phacotrabeculectomy With Collagen Matrix Implant (Ologen®) Versus Mitomycin C

Start date: June 2, 2014
Phase: Phase 2
Study type: Interventional

1. Study objective: To assess the efficacy and safety of collagen matrix implant (Ologen®; OLO) in phacotrabeculectomy and to compare with mitomycin C (MMC) augmented phacotrabeculectomy. 2. Study Design: The study is designed as a prospective randomized trial. Patient who meet the inclusion/exclusion criteria and sign the informed consent form will be included for this study. 3. Follow-Up: This investigation is including 7 post-operative visits and follow-up within 12 months from the date of surgery. Patients should be seen at postoperative days 1, 7, 30, 90, 180, 270 and 360.

NCT ID: NCT03500198 Completed - Cataract Clinical Trials

Clinical Investigation of the Next Generation Intraocular Lens

Start date: June 28, 2018
Phase: N/A
Study type: Interventional

An investigational IOL designed to provide improved intermediate and near visual acuity and decreased spectacle wear was evaluated for safety and effectiveness in a six-month study.

NCT ID: NCT03499873 Completed - Cataract Clinical Trials

Clinical Endpoint Study of Nepafenac 0.3% Opthalmic Suspension

Start date: March 28, 2018
Phase: Phase 3
Study type: Interventional

A randomized, multicenter, double masked, placebo controlled, parallel group, bioequivalence study to evaluate the clinical equivalence and safety of Nepafenac 0.3% ophthalmic suspension (manufactured by Indoco remedies Ltd. for Actavis LLC) with IlevroTM (Nepafenac ophthalmic suspension), 0.3% of Alcon Laboratories, Inc. for the treatment of pain and inflammation associated with cataract surgery.

NCT ID: NCT03497481 Completed - Cataract Clinical Trials

Neopterin Dosage in the Eye

CHA
Start date: June 22, 2018
Phase:
Study type: Observational

The purpose of the study is to determine whether neopterin can be dosed in the fluid of the eye's anterior chamber for patient with non-inflammatory and non-infectious ophthalmic pathology.

NCT ID: NCT03496467 Completed - Pain Clinical Trials

Safety/Efficacy of Nepafenac Punctal Plug Delivery System Compared to Placebo to Control Ocular Pain/Inflammation After Cataract

Start date: March 5, 2018
Phase: Phase 2
Study type: Interventional

This is a Phase 2, multi-center, randomized, parallel-arm, double-masked, placebo-controlled study. One (1) to 2 days prior to their scheduled cataract surgery, each study subject will be randomized (2:1) in to one of two treatment groups: N-PPDS or p-PPDS, which are inserted in the lower punctum of the subject's scheduled surgical eye. All plugs will remain in the study subject's lower punctum for a period of 2 weeks following cataract surgery.

NCT ID: NCT03494257 Completed - Cataract Clinical Trials

Effect of Fixed Brinzolamide-brimonidine Combination on Intraocular Pressure After Phacoemulsification

Start date: September 4, 2017
Phase: N/A
Study type: Interventional

This study aims to evaluate the effect of fixed brinzolamide-brimonidine combination on intaocular pressure after uncomplicated phacoemulsification surgery. Patients scheduled for phacoemulsification will be randomly assigned to 1 of 2 groups. The treatment group will receive 1 drop of brimonidine-brinzolamide fixed combination immediately after surgery, and the control group will receive no treatment. The IOP will be measured preoperatively and at 6, 12, and 24 hours postoperatively.

NCT ID: NCT03479944 Completed - Cataract Clinical Trials

Clinical Evaluation of FLACS With Combination of LenSx® and Centurion®

Start date: August 22, 2018
Phase: N/A
Study type: Interventional

The purpose of this study is to evaluate cumulative dissipated energy (CDE), endothelial cell loss, and average torsional amplitude with combination of LenSx® and Centurion® compared to conventional cataract surgery.

NCT ID: NCT03470584 Completed - Stroke Clinical Trials

Vegetarian Diet and Chronic Degenerative Diseases

Start date: March 1, 2005
Phase:
Study type: Observational

To investigate the prospective association between a vegetarian diet and chronic degenerative diseases in two cohorts of Taiwanese Buddhists

NCT ID: NCT03458442 Completed - Cataract Clinical Trials

China OLIMPICS: China Ophthalmic Learning and Improvement Initiative in Cataract Surgery Trial

Start date: May 9, 2018
Phase: N/A
Study type: Interventional

This is a prospective, investigator-masked randomised controlled education-intervention trial of intense simulation-based surgical education plus conventional training versus a current six-week standard training course. The aim is to investigate whether the addition of simulation-based surgical education to standard training improves competence and surgical outcomes. All participants in the study will receive the educational intervention of the six-week Orbis-COS course. The intervention groups will receive this training and an additional element of learning and sustained deliberate practice using model eyes and simulation.

NCT ID: NCT03455114 Completed - Cataract Clinical Trials

A Single-arm, Open-label Feasibility Study for Assessing the Safety and Performance of the Modified AssiAnchor

cataracts
Start date: March 24, 2018
Phase: N/A
Study type: Interventional

The AssiAnchor 2 is a fixation ophthalmic device. The device is manufactured by Hanita Lenses from PMMA material which is being used for the production of Intra-ocular lenses. The device is intended for patients requiring capsule centration to clip the anterior lens capsule between the arms of the device and secure it to the scleral wall.