Clinical Trials Logo

Caries clinical trials

View clinical trials related to Caries.

Filter by:

NCT ID: NCT04933123 Active, not recruiting - Caries Clinical Trials

Clinical Evaluation of a Dental Glass Ceramic in the Indirect Restorative Therapy

Start date: September 14, 2021
Phase: N/A
Study type: Interventional

A post market clinical follow up study (PMCF) with a glass ceramic to ensure the safety and efficacy of the product. It is a study with single-arm in which inlays and onlays for molars and premolars are adhesively luted.

NCT ID: NCT04906291 Completed - Caries Clinical Trials

The Preventive Effect of 2-years Use of Hydroxyapatite Containing Toothpastes in Children.

Start date: February 1, 2018
Phase: N/A
Study type: Interventional

The aim of this RCT was to verify the caries preventive efficacy of toothpastes containing biomimetic hydroxyapatite (H.A.) complex in children compared to traditional fluoridated toothpastes. In total 610 children of two age groups (4-5 years and 6-7 years at baseline) were enrolled. Four toothpastes, two containing fluoride-substituted hydroxyapatite (H.A.F.) (1000 and 1450 ppm F-) and magnesium-, strontium-, carbonate-substituted hydroxyapatite, in a chitosan matrix and two traditional fluoridated toothpastes (1000 and 1450 ppm F-) without other active components were administered randomly to two groups with younger children (Gyoung) and to two groups with older children those containing1450 ppm F (GOLD) during 24 months. A standardized questionnaire was administered to parents/caregivers to gain information regarding caries risk factors. Caries evaluation was performed at school using ICDAS, scoring lesions as initial (up to score 2), moderate (scores 3-4) and severe (scores 5-6).

NCT ID: NCT04889196 Not yet recruiting - Caries Clinical Trials

The Efficiency and Gingival Health Status of Hall Versus SDF Techniques in the Management of Carious Primary Molars

Start date: September 1, 2021
Phase: Phase 3
Study type: Interventional

PICO question: In Comparison to the hall technique , will silver diamine fluoride have equalvent gingival health status in treatment of carious primary molars? population: children suffering from caries . intervention : silver diamine fluoride. comparison: hall technique outcome: Primary outcome: Gingival health measurement device modified gingival index, measurement unit score(0-1-2) Secondary outcomes: 1. Oral hygiene measurement device modified plaque index , measurement unit score (0-1-2) 2. Time of Treatment measurement device digital chronometer, measurement unit minutes

NCT ID: NCT04796974 Active, not recruiting - Caries Clinical Trials

Clinical Evaluation of "Cention Forte" Restorative Material

Start date: March 8, 2021
Phase: N/A
Study type: Interventional

Resin composites, the first choice of material for the restoration of posterior teeth, still have several drawbacks including their polymerization shrinkage and potential failure of the resin-dentin interface leading to secondary caries. Time-saving and simplified restorative procedures are an ongoing demand for posterior applications.The bulk-fill resin based composites (BF-RBCs), has been developed with an attempt to speed up the restoration process by enabling up to 4- or 5-mm thick increments to be cured in one step. The photo-polymerized single-step BF-RBC materials seem to have some limitations in terms of adequate polymerization. Therefore, recently, the use of dual-polymeritzed RBCs that are also suitable for bulk-fill application with additional bioactive properties such as acid-neutralizing ion release has been offered as an alternative to photo-polymerized ones. Cention N (Ivoclar Vivadent, Schaan, Liechtenstein) restorative material is one approach that has been introduced as a new material category for this purpose. The hand mixed form is named as Cention N whereas auto-mixed capsule form is Cention. Both of them are resin based composite materials categorised as 'alkasite'. They are self-curing composites with optional photo-polymerzation for full volume (bulk) placement. Their composition is same with only exception of the concentration of the initiators and the powder liquid proportion. Cention is delivered together with Cention Primer to ensures the retention of the filling independent of the preparation. The objective of this prospective clinical trial is to evaluate the clinical performance of Cention and Cention Primer in restoration of Class I and II cavities.

NCT ID: NCT04794426 Not yet recruiting - Caries Clinical Trials

Post-operative Pain and Child Behavior of Hall Technique Versus SDF in the Management of Carious Primary Molars: RCT

Start date: June 1, 2021
Phase: Phase 3
Study type: Interventional

PICO question: Papulation: children suffering from caries Intervention: Silver Diamine Fluoride Comparison: Hall technique Outcome: Primary Outcome: Intraoperative and postoperative pain Measurement device: Face pain scale Revised8 Measurement unit: Score 0-2-4-6-8-10 Secondary Outcome: 1. Child Anxiety Measurement device: Venham Anxiety rating scale 9 Measurement unit: Six-point scales 0-1-2-3-4-5 2. Child Behavior Measurement device: Venham Behavior rating scale 9 Measurement unit: Six-point scales 0-1-2-3-4-5

NCT ID: NCT04763044 Completed - Caries Clinical Trials

Evaluation of the Fluoride Dose Response Using In Situ Caries Model

Start date: March 1, 2021
Phase: Phase 4
Study type: Interventional

The purpose of this study is to evaluate the fluoride dose response of different dentifrice fluoride concentrations - 0, 250, 1100 and 2800 ppm fluoride as sodium monofluorophosphate (MFP) and a fifth leg of 1100 ppm Stannous Fluoride (SnF2) using an in situ caries model.

NCT ID: NCT04708223 Active, not recruiting - Caries Clinical Trials

Prospective, Split-mouth, Comparative Study to Compare Clinical Outcomes of Two Different Posterior Composite

Start date: September 1, 2018
Phase: N/A
Study type: Interventional

The objective of this 2-year split mouth comparative study, a randomized controlled study, is to determine whether the simplified placement procedure of the ultra-rapid polymerizing Tetric PowerFlow/ Tetric PowerFill with a reduced light polymerization time (3 s), yields the same clin-ical results as widely used commercially available dental composites (Tetric EvoCeram Bulk Fill, Tetric EvoFlow Bulk Fill) requiring up to 40 seconds of light polymerization time.

NCT ID: NCT04679558 Completed - Caries Clinical Trials

Antibacterial Effect of Chlorhexidine Added to the Preventive Protocol in Adolescent Special Needs

Start date: September 15, 2020
Phase: Early Phase 1
Study type: Interventional

This study ia conducted to know the antibacterial effect of chlorhexidine on the mouth flora speciallly in adolescent special needs who can't hold the tooth brush properly

NCT ID: NCT04676230 Completed - Caries Clinical Trials

Effectiveness of an ICCMS™ Caries Management Program.

Start date: March 2014
Phase: N/A
Study type: Interventional

The aim of this study is to compare in schoolchildren the effectiveness of an updated caries management program based on the current caries paradigm with the ICCMS™ system (International Caries Classification and Management System) versus an adjusted Colombian dental public health service caries management program, in terms of: 1- caries risk probability, 2- caries lesions, 3- parents' knowledge, attitudes and practices regarding children's oral health. Null hypothesis: the caries management program based on its current paradigm offers the same degree of effectiveness than the conventional caries management program. Alternative hypothesis: the caries management program based on its current paradigm offers a different degree of effectiveness than the conventional caries management program.

NCT ID: NCT04645693 Recruiting - HIV Clinical Trials

The Impact of Oral Health in HIV Patients on Antiretroviral Therapy

OHART
Start date: February 24, 2021
Phase:
Study type: Observational [Patient Registry]

This is a prospective cohort study designed to investigate the range of metabolic abnormalities observed in patients living with HIV on antiretroviral therapy. This study will also explore the concurrent role of poor oral health in supporting and driving chronic immune activation and inflammation in HIV infection.