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NCT ID: NCT06438926 Not yet recruiting - Caries Clinical Trials

Prevalence of Dental Caries in Patients With Dental Crowding

Start date: September 2024
Phase:
Study type: Observational

Dental crowding causes limited access for the toothbrush, and the natural cleansing effect of the teeth by the tongue and saliva is also limited. This malposition allows for prolonged food accumulation, bacterial and plaque retention, which are important factors for the initiation and progression of dental caries.

NCT ID: NCT06098911 Not yet recruiting - Caries Clinical Trials

Modified Atraumatic Restorative Treatment Using CPP ACP

Start date: February 10, 2024
Phase: N/A
Study type: Interventional

To evaluate the clinical and radiographic success of using Casein Phosphopeptide Amorphous Calcium Phosphate (CPP-ACP) under glass ionomer restorations in atraumatic restorative treatment as a biomimetic approach in pediatric dentistry.

NCT ID: NCT05569850 Not yet recruiting - Gingivitis Clinical Trials

Efficacy of an Antibacterial Toothpaste and Patients' Satisfaction

Start date: November 1, 2022
Phase: N/A
Study type: Interventional

The primary objective of this randomized controlled clinical trial (RCCT) will be to compare the efficacy in reducing the quantity of Streptococcus mutans (S. Mutans) in saliva of a recently introduced toothpaste compared to a commercially available toothpaste. The secondary outcomes will be to assess patients' impression of the toothpastes (in terms of taste, satisfaction etc.), and to investigate potential changes in dentin hypersensitivity, plaque formation and gingival inflammation.

NCT ID: NCT05314842 Not yet recruiting - Caries Clinical Trials

Pulpotomy in Primary Molars Treated With Premixed Bio-ceramic MTA Versus Formocresol

Start date: April 1, 2022
Phase: Phase 3
Study type: Interventional

examine the results of pulpotomy in primary molars using premixed bioceramic MTA versus Formocresol. Clinical and radiographic success rates were used as outcomes.

NCT ID: NCT05301439 Not yet recruiting - Caries Clinical Trials

Use Of Hall Technique In Deciduous Molars Affected By Extensive Caries Lesions

Start date: June 20, 2023
Phase: Phase 1/Phase 2
Study type: Interventional

Despite preventive treatments and the promotion of oral health, dental caries is one of the most prevalent chronic diseases in the population and treatment of caries lesions in deciduous teeth is a fundamental procedure aimed at increasing the resistance of the remaining tooth structure to preserve the permanent dentition. The present study aims to make a clinical evaluation of the Hall Technique compared to direct restorations with universal adhesives and bulk fill resins in large destruction of deciduous teeth. 90 children between 5 and 10 years old, healthy, of both sexes, without distinction of race, enrolled in the clinics of Universidade Metropolitana de Santos-UNIMES will be selected. The in-office treatments will be carried out by a trained researcher, according to the manufacturer's instructions for each material and scientific evidence on the respective topic. Participants will be divided into 03 groups according to the proposed treatments. Group 1 - Universal adhesive restorative procedure + condensable bulk fill resin; Group 2 - Hall Technique with Shofu steel crowns and Group 3 - Steel crown with conventional technique. The evaluated outcomes will be: effectiveness of the technique and longevity of the restorations.

NCT ID: NCT05249231 Not yet recruiting - Caries Clinical Trials

Parental Satisfaction of Hall Technique Versus SDF in the Management of Carious Primary Molars

Start date: April 2022
Phase: N/A
Study type: Interventional

- The aim of this study is to assess parental satisfaction and duration of the procedure of Hall and silver diamine fluoride techniques in the treatment of carious primary molars with healthy pulp. - primary ourcome: parental satisfaction measurement device: four point likert scale measurement unit: 1-2-3-4 - secondary outcome: duration of the procedure measurement device: Digital chronometer measurement unit: minutes

NCT ID: NCT05236205 Not yet recruiting - Caries Clinical Trials

Antimicrobial Photodynamic Therapy as an Adjunct for Management of Deep Caries Lesions

Start date: May 30, 2022
Phase: Phase 2
Study type: Interventional

Alternatively to conventional treatments, chemo-mechanical caries removal agents can be used. A modality of treatment that has been increasing in dentistry is antimicrobial photodynamic therapy (aPDT). Bixa orellana, is being researched for application in aPDT. This protocol aims to determine the effectiveness of aPDT with Bixa orellana extract in deep caries lesions. Methods and analysis: A total of 160 teeth with deep occlusal dental caries will be selected and divided in 3 groups: G1 - control group (Caries removal with a lowspeed drill); G2 - Partial Caries Removal with Papacarie; G3 - Partial Caries Removal with Papacarie and application Bixa orellana extract (20%); G4 - Partial Caries Removal with Papacarie and application Bixa orellana extract (20%) with LED (aPDT). After treatment, all the teeth will be restored with glass ionomer cement and followed up clinically and radiographically, with evaluations at immediately, 1 week, 1, 3, 6, and 12 months. Dentin samples before and after treatment will be analyzed microbiologically. The data will be submitted to descriptive statistical analysis of the association between the categorical variables using the chi-square test and Fisher exact text. The Student t test and analysis of variance will be used for the comparison of mean signs and symptoms of reversible pulpitis. Pearson correlation coefficients will be calculated for the analysis of correlations among the continuous variables.

NCT ID: NCT05127343 Not yet recruiting - Caries Clinical Trials

Comparison Between Resin Based and Glass Ionomer Based Hydrophilic Fissure Sealants

Start date: February 2022
Phase: N/A
Study type: Interventional

The aim of the study is to clinically evaluate the retention and caries formation of hydrophilic fissure sealants among adolescents after one year.

NCT ID: NCT05109299 Not yet recruiting - Caries Clinical Trials

Antibacterial Effect of Miswak Toothpaste Compared to Fluoride Toothpaste

Start date: December 1, 2021
Phase: N/A
Study type: Interventional

Meswak is scientifically formulated herbal toothpaste with pure extract of the Miswak plant 'Salvadore Persica', the famous 'Toothbrush Tree' used for centuries. The astringent and anti-bacterial properties of Meswak helps reduce tooth decay , fight plaque and prevent gum diseases. Miswak Herb is a rare, potent, priceless, wonder herb that delivers incredible Dental Care benefits.

NCT ID: NCT05070416 Not yet recruiting - Caries Clinical Trials

Lithium Disilicate Crowns Study

Start date: October 1, 2021
Phase: N/A
Study type: Interventional

CAD-CAM crowns made of lithium disilicate are placed in patients by using either a dual-curing adhesive or a self-adhesive luting material in combination with total etch/universal bonding agent.