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Caries clinical trials

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NCT ID: NCT05748327 Active, not recruiting - Caries Clinical Trials

Trial With Two New Tooth-colored Restorative Materials in Class I/II Cavities

Start date: November 22, 2022
Phase: N/A
Study type: Interventional

This is a randomized-controlled clinical trial to investigate the success rate of two new tooth-colored restorative materials in class I and II cavities over 5 years according to FDI criteria scores (1, 2 and 3).

NCT ID: NCT05311657 Active, not recruiting - Quality of Life Clinical Trials

Oral Health and Severe COPD

Start date: September 21, 2020
Phase:
Study type: Observational

This case-control study aims to investigate the association of severe COPD with oral health.

NCT ID: NCT05033015 Active, not recruiting - Caries Clinical Trials

Effect of Enzyme-containing Mouth Rinse on Dental Biofilm in Patients With Fixed Orthodontic Appliances

Start date: March 1, 2021
Phase: N/A
Study type: Interventional

Caries is a biofilm-mediated global public health problem causing health, social and economic consequences for individuals, communities and countries. Treatment with fixed orthodontic appliances is associated with impaired oral hygiene. This results in a demineralization of the enamel (white spot lesions). The prevalence is fairly high (30-50%) among adolescents and self-applied fluorides cannot completely prevent such lesions. It is therefore important to investigate novel approaches to combat these unwanted adverse effects. A systematic review has suggested that mouthwashes may be suitable technology to control biofilm accumulation in orthodontic patients. The aim of the present pilot study is to evaluate the effect of a novel mouth rinse containing a blend of natural enzymes in addition to fluoride on the presence of oral biofilm in patients undergoing treatment with fixed orthodontic appliances.

NCT ID: NCT04933123 Active, not recruiting - Caries Clinical Trials

Clinical Evaluation of a Dental Glass Ceramic in the Indirect Restorative Therapy

Start date: September 14, 2021
Phase: N/A
Study type: Interventional

A post market clinical follow up study (PMCF) with a glass ceramic to ensure the safety and efficacy of the product. It is a study with single-arm in which inlays and onlays for molars and premolars are adhesively luted.

NCT ID: NCT04796974 Active, not recruiting - Caries Clinical Trials

Clinical Evaluation of "Cention Forte" Restorative Material

Start date: March 8, 2021
Phase: N/A
Study type: Interventional

Resin composites, the first choice of material for the restoration of posterior teeth, still have several drawbacks including their polymerization shrinkage and potential failure of the resin-dentin interface leading to secondary caries. Time-saving and simplified restorative procedures are an ongoing demand for posterior applications.The bulk-fill resin based composites (BF-RBCs), has been developed with an attempt to speed up the restoration process by enabling up to 4- or 5-mm thick increments to be cured in one step. The photo-polymerized single-step BF-RBC materials seem to have some limitations in terms of adequate polymerization. Therefore, recently, the use of dual-polymeritzed RBCs that are also suitable for bulk-fill application with additional bioactive properties such as acid-neutralizing ion release has been offered as an alternative to photo-polymerized ones. Cention N (Ivoclar Vivadent, Schaan, Liechtenstein) restorative material is one approach that has been introduced as a new material category for this purpose. The hand mixed form is named as Cention N whereas auto-mixed capsule form is Cention. Both of them are resin based composite materials categorised as 'alkasite'. They are self-curing composites with optional photo-polymerzation for full volume (bulk) placement. Their composition is same with only exception of the concentration of the initiators and the powder liquid proportion. Cention is delivered together with Cention Primer to ensures the retention of the filling independent of the preparation. The objective of this prospective clinical trial is to evaluate the clinical performance of Cention and Cention Primer in restoration of Class I and II cavities.

NCT ID: NCT04708223 Active, not recruiting - Caries Clinical Trials

Prospective, Split-mouth, Comparative Study to Compare Clinical Outcomes of Two Different Posterior Composite

Start date: September 1, 2018
Phase: N/A
Study type: Interventional

The objective of this 2-year split mouth comparative study, a randomized controlled study, is to determine whether the simplified placement procedure of the ultra-rapid polymerizing Tetric PowerFlow/ Tetric PowerFill with a reduced light polymerization time (3 s), yields the same clin-ical results as widely used commercially available dental composites (Tetric EvoCeram Bulk Fill, Tetric EvoFlow Bulk Fill) requiring up to 40 seconds of light polymerization time.

NCT ID: NCT02479711 Active, not recruiting - Caries Clinical Trials

A Clinical Evaluation of a Glass Ionomer Cement (GIC) Based Restorative System Versus Bulk Filled Resin-based Composite

Start date: January 2014
Phase: N/A
Study type: Interventional

The aim of the present study is to evaluate the clinical performance of EQUİA restoration material in Class II cavities comparing with a resin-based composite / dentin bonding system.

NCT ID: NCT00738647 Active, not recruiting - Caries Clinical Trials

Assessment of a New Resin-based Composite Filling Material

Start date: May 2007
Phase: N/A
Study type: Interventional

Evaluation of a new resin-based composite material. Amalgam and composite are the most commonly used restorative materials in dentistry. Due to the toxicity of mercury and the subsequent environmental problems, the search for alternatives continues and search into new composite restorative materials intensifies. The presently available composites have improved, but shrinkage of the composite during the curing procedure is still a clinical problem. A new composite restorative material has among other advantages demonstrated lower shrinkage in laboratory studies, due to a new formulation of the material. This project aims to study the clinical performance of this new composite compared to a commonly used composite restoration material. 72 patients (158 teeth) are allocated to the project which is carried out at the School of dentistry, University of Aarhus, Denmark.

NCT ID: NCT00502606 Active, not recruiting - Periodontitis Clinical Trials

a Clinical Study.the Effect of Addition of Insoluble Antibacterial Nanoparticles(IABN) in Resin Base Provisional Cement

IABN
Start date: February 2007
Phase: N/A
Study type: Observational

The effect of Antibacterial Nanoparticles, Incorporated in cement, on S.mutans in the margins of provisional restorations is going to be examined clinically by using two kinds of provisional cement 1. cement with out antibacterial nanoparticles. 2.cement with small addition of IABN. after one week in the mouth the crowns are to be removed and examined for the presence and quantity of s. mutans. in vitro tests of the same has shown significant reduction in bacterial population around the provisional cement as compared to the regular cement.

NCT ID: NCT00357877 Active, not recruiting - Caries. Clinical Trials

Prevention of Adult Caries Study (PACS)

Start date: July 2006
Phase: Phase 3
Study type: Interventional

Adult tooth decay is an infectious disease that afflicts the majority of Americans aged 55 and older and is the most common chronic disease at midlife with an ever growing economic toll. Despite the fact that specific bacteria cause tooth decay, no FDA-approved anti-microbial treatment for decay is available to the American dental professional. The Prevention of Adult Caries Study (PACS) is a study is designed to evaluate the efficacy of a topical, temporary, 10% w/v chlorhexidine dental coating in reduce new decay in adult dental patients at risk for decay.