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Pain Inflammation and Cannabis in HIV — PITCH-E  

HIV Infections Clinical Trial

Official title:
The Impact of Medical Cannabis on Pain and Inflammation in People Living With HIV

Clinical Trial Summary

This study will examine how medical cannabis use affects neuropathic pain, inflammation and adverse events in people living with HIV (PLWH) with neuropathic pain. The investigators will observe how varying ratios of THC (tetrahydrocannabinol) and CBD (cannabidiol) in medical cannabis impact neuropathic pain, inflammation and adverse events.

Clinical Trial Description

This study will examine how medical cannabis use affects neuropathic pain in PLWH with neuropathic pain. The investigators will enroll adults with HIV who have a) neuropathic pain, b) are actively certified for medical cannabis, and c) intend to have soft gel capsule products dispensed at Vireo (medical cannabis dispensary). The investigators will observe how pain and inflammation change in participants after they are randomized to receive high THC:low CBD product, an equal THC:CBD product, a low THC:high CBD product, or placebo by our collaborator in a separate study. Over 14 weeks, data sources will include questionnaires, blood samples, urine samples; medical, pharmacy, and Prescription Monitoring Program (PMP) records. The primary independent variable will be type of medical cannabis product dispensed at dispensary, and the primary outcome will be self-reported pain. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05554146
Study type Interventional
Source Montefiore Medical Center
Contact
Status Completed
Phase N/A
Start date October 28, 2022
Completion date May 3, 2024
View Details
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