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NCT ID: NCT03878862 Recruiting - Rotator Cuff Tear Clinical Trials

Surgical Management of Irreparable RC Tears

Start date: April 1, 2019
Phase:
Study type: Observational

The primary goal will be to compare the early postoperative recovery outcomes and complications from a series of surgical treatments for massive or irreparable rotator cuff tears. The secondary goal will be to assess factors that impact the outcomes of these reconstructions for irreparable posterosuperior rotator cuff tears.

NCT ID: NCT03879135 Recruiting - Clinical trials for Von Willebrand Disease (VWD)

A Study of Recombinant Von Willebrand Factor (rVWF) in Pediatric and Adult Participants With Severe Von Willebrand Disease (VWD)

Start date: April 1, 2019
Phase: Phase 3
Study type: Interventional

The main aim of the study is to check effectiveness of rVWF (vonicog alfa) prophylaxis based on the annualized bleeding rate (ABR) of spontaneous (not related to trauma) bleeding episodes in pediatric and adult participants during the first 12 months on study treatment. The participants will be treated with rVWF for a maximum of 3 years. Their von Willebrand Disease will be treated according to Investigational product (IP) dosing directions.

NCT ID: NCT03880045 Recruiting - Myoma Clinical Trials

Topical Tranexamic Acid Plus Perivascular Vasopressin at the Time of Abdominal Myomectomy

Start date: April 1, 2019
Phase: N/A
Study type: Interventional

In this study, the investigators will investigate the effectiveness of a topical tranexamic acid plus perivascular vasopressin compared with perivascular vasopressin alone for the reduction of blood loss at the time of myomectomy

NCT ID: NCT03880604 Recruiting - Myoma Clinical Trials

Triple Tourniquets With or Without Tranexamic Acid for Reducing Blood Loss at Open Myomectomy

TTT
Start date: April 1, 2019
Phase: N/A
Study type: Interventional

In this study, the investigators will investigate the effectiveness of an intravenous tranexamic acid plus triple tourniquets compared with triple tourniquets alone for the reduction of blood loss at the time of myomectomy

NCT ID: NCT03881345 Recruiting - Pulmonary Embolism Clinical Trials

Ongoing Registry of Treatment of Venous Thromboembolism

RRT VTE
Start date: April 1, 2019
Phase:
Study type: Observational [Patient Registry]

Ongoing registration of patients with venous thromboembolism treated by means of antithrombotic therapy, thrombolisys, open surgery, endovenous desobstruction and stenting.

NCT ID: NCT03881384 Recruiting - Breast Neoplasms Clinical Trials

Circulating Tumor DNA as Marker of Therapeutic Efficacy in Breast Cancer Patients

Start date: April 1, 2019
Phase:
Study type: Observational

In nonmetastatic local advanced breast cancer patients, we are going to investigate whether circulating tumor DNA (ctDNA) detection can reflect the tumor response to neoadjuvant chemotherapy (NCT) and detect minimal residual disease after surgery.

NCT ID: NCT03884205 Recruiting - Gemcitabine Clinical Trials

GDPE/CEOPE Compared With CEOPE for Newly Diagnosed Patients With PTCL

Start date: April 1, 2019
Phase:
Study type: Observational [Patient Registry]

Peripheral T-cell Lymphoma (PTCL) is a heterogenic malignancy with poor outcome. There is no standardized treatment protocol for this kind of lymphoma. So, clinical trials are encouraged by National Comprehensive Cancer Network (NCCN) for those patients. Former studies confirmed that GDP (Gemcitabine, Dexamethasone, and Cis-platinum) is superior with CHOP (Cyclophosphamide, Adriamycin, Vincristine, and Prednisone). Combination with etoposide can improve the outcome of some patients with high risk factors. The aim of our study is to compare the response and survival rate of GDPE/CEOPE (gemcitabine, cis-platinum, etoposide, and dexamethasone/cyclophosphamide, vincristine, pharmorubicin, etoposide, and prednisone) with those of CEOPE regimen, looking forward to its superiority in efficacy and safety for the newly diagnosed adult patients with PTCL.

NCT ID: NCT03884361 Recruiting - Vaginal Microbiome Clinical Trials

Does Elective Amniocentesis Change Vaginal Microbiome?

Start date: April 1, 2019
Phase: N/A
Study type: Interventional

the aim of this study is to check if elective amniocentesis change vaginal microbiome

NCT ID: NCT03884764 Recruiting - Chronic Pain Clinical Trials

Ganglion Impar Denervation and Radiofrequency on Sacral Root 3 for Chronic Prostatic Pain

Start date: April 1, 2019
Phase: N/A
Study type: Interventional

the authors will evaluate the added analgesic benefit of pulsed radiofrequency on sacral root 3 with ganglion impar denervation on chronic pelvic pain due to chronic prostatitis

NCT ID: NCT03886922 Recruiting - Headache Clinical Trials

The Hemodynamics Effect of Glibenclamide on Levcromakalim Assessed by High Resolution Magnetic Resonance Angiography (MRA) Technique in a Randomized Double-blind Cross-over Placebo-controlled Study With Healthy Volunteers

Start date: April 1, 2019
Phase: N/A
Study type: Interventional

To investigate the effect of levcromakalim/placebo infusion on cranial arteries after glibenclamide administration.