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NCT ID: NCT03930056 Recruiting - Spinal Cord Injury Clinical Trials

C-Brace II Spinal Cord Injury

Start date: April 16, 2019
Phase: N/A
Study type: Interventional

A randomized, repeated measures comparative design study to compare use of a micro-processor controlled knee-ankle-foot orthosis vs. traditional care knee-ankle-foot-orthosis (KAFO) models following discharge from inpatient rehabilitation.

NCT ID: NCT03950635 Recruiting - Melanoma Clinical Trials

Dietary Intervention in Patients With a History of Melanoma

Start date: April 16, 2019
Phase: Phase 1
Study type: Interventional

This research trial studies the effects of diet in patients with a history of melanoma. We are studying the impact of 2 different diets; a whole-foods, fiber-rich diet and a ketogenic diet. Participants will be assigned to one of these diets. During this study, participants will be provided all food at no cost for the entire 6-week study. Food can be picked up or shipped to the participant's home. However, participants will need to come into MD Anderson Cancer Center in Houston, TX, for the initial screening visit and for blood tests every 2 weeks during the study.

NCT ID: NCT03982641 Recruiting - Colorectal Cancer Clinical Trials

Emilia-Romagna Surgical Colorectal Cancer Audit- ESCA

ESCA
Start date: April 16, 2019
Phase:
Study type: Observational [Patient Registry]

Focus of this project is to evaluate the possible financial benefit resulting from an optimization of surgical outcomes throughout a collaborative and systematic auditing activity.The primary objective of this analysis is to assess the employed resources by National Health System related to surgical activities for primary colorectal cancer during a collaborative and systematic auditing activity in 8 Surgical Units of Emilia-Romagna

NCT ID: NCT04187495 Recruiting - AML Clinical Trials

Study of MAX-40279 in Patients With Relapsed or Refractory Acute Myelogenous Leukemia (AML)

Start date: April 16, 2019
Phase: Phase 1
Study type: Interventional

This is a non-randomized, open-label, single-arm, dose-escalation Phase I study to evaluate the safety and tolerability of MAX-40279-01 in patients with Relapsed or Refractory AML.

NCT ID: NCT04282993 Recruiting - Atrial Fibrillation Clinical Trials

Wearable Devices for Secondary Prevention of Ischemic Stroke

Start date: April 16, 2019
Phase: N/A
Study type: Interventional

Ischemic stroke is an important cause of death and disability in Western countries. Different risk factors have been identified such as hypertension, diabetes, dyslipidemia, smoke, atrial fibrillation, obesity, and sedentary. The aim of this study is to evaluate the feasibility of an approach based on the use of wearable devices for the identification and reduction of risk factors in patients with previous history of ischemic stroke or transient ischemic attack.

NCT ID: NCT04322942 Recruiting - Sepsis Clinical Trials

Sepsis Prediction by Monocyte Distribution Width and Procalcitonin

Start date: April 16, 2019
Phase:
Study type: Observational

The mortality rate of sepsis remains as high as 30 to 40%. Early diagnosis and treatment of patients with sepsis reduce mortality significantly. The most commonly used biomarkers in clinical practice are C-reactive protein (CRP) and procalcitonin (PCT). In terms of exploring new diagnostic tools of sepsis, monocyte distribution width (MDW) was first reported in 2017. It was reported as part of the white blood cell (WBC) differential count. MDW greater than 20 and abnormal WBC count together were reported to provide a satisfactory accuracy. The area under curve (AUC) in predicting sepsis-2 is 0.852. It was proposed as a novel diagnostic tool of sepsis in the emergency setting. Nonetheless, the performance of MDW compared with the conventional biomarkers remained unknown. The aim of this study was to compare the diagnostic accuracy of MDW and PCT on sepsis in the emergency department.

NCT ID: NCT03803553 Recruiting - Clinical trials for Stage III Colon Cancer

Identification and Treatment Of Micrometastatic Disease in Stage III Colon Cancer

Start date: April 16, 2020
Phase: Phase 3
Study type: Interventional

This research study is comparing two standard of care treatment options based on blood test results for participants who have metastatic colon cancer. The names of the potential treatments involved in this study are: - Active surveillance - FOLFIRI treatment - Nivolumab treatment - Encorafenib/Binimetinib/Cetuximab treatment - Trastuzumab + Pertuzumab

NCT ID: NCT04322890 Recruiting - Clinical trials for Non Small Cell Lung Cancer

Treatment Strategies and Survival Outcome for Non-small Cell Lung Cancer With Oncogenic Mutation

PIKACHU
Start date: April 16, 2020
Phase: Phase 2
Study type: Interventional

The purpose of this study is to assess the Treatment Strategies and Survival Outcome for Non-small Cell Lung Cancer With Oncogenic Mutation.

NCT ID: NCT04338568 Recruiting - COVID-19 Pneumonia Clinical Trials

Screening COVID-19 by Point-of-care Lung Ultrasound: a Validation Study

SCOUT
Start date: April 16, 2020
Phase: N/A
Study type: Interventional

COVID-19 is a rapidly spreading and very contagious disease caused by a novel coronavirus that can lead to respiratory insufficiency. In many patients, the chest radiograph at first presentation be normal, and early low-dose CT-scan is advocated to diagnose viral pneumonia. Lung ultrasound (LUS) has similar diagnostic properties as CT for diagnosing pneumonia. However, it has the advantage that it can be performed at point-of-care, minimizing the need to transfer the patient, reducing the number of health care personnel and equipment that come in contact with the patient and thus potentially decrease the risk of spreading the infection. This study has the objective to examine the accuracy of lung ultrasound in patients with proven COVID-19 pneumonia.

NCT ID: NCT04339166 Recruiting - Infertility Clinical Trials

Embryo Selection by Noninvasive Preimplantation Genetic Test

ESNi-PGT
Start date: April 16, 2020
Phase: N/A
Study type: Interventional

The objective of this study is to explore whether non-invasive chromosome screening (NICS) can be used as an effective indicator for embryos selection besides morphology through a multicenter randomized controlled trial, by comparing the differences of live birth rate, pregnancy rate and miscarriage rate between the two groups of embryo selection by "NICS+ morphology" and embryo selection only by "morphology" in IVF cycle.