There are more than 498,563 clinical trials published worldwide with over 60,000 trials that are currently either recruiting or not yet recruiting. Use our filters on this page to find more information on current clinical trials or past clinical trials (free or paid) for study purposes and read about their results.
Hip replacement surgery is common, with over 60,000 cases in Canada annually. After hip replacement, about 1-2% patients develop a deep infection in their artificial hip implant, called a periprosthetic joint infection (PJI). It can results in severe pain, disability and death. There are two types of surgical treatment: a single-stage revision that involves removing the joint, thoroughly cleaning the infected area and implanting a new joint, all in the same surgical procedure; a two-stage revision involves removing the joint, waiting at least 8 weeks while treating the patients with antibiotics and then doing re-implantation of the joint.
To determine whether an indwelling low profile Kohli Atraumatic Catheter causes less macro-morphologic inflammation and edema to the bladder mucosa than a traditional indwelling Foley catheter as assess by computerized image analysis.
One in three Black boys born today in the United States will be incarcerated at some point in their lifetime, compared to one in 17 White boys. Black males are more likely to be arrested, convicted, and given unfair sentences. Black youth comprise of 16% of the Nation's public schools, but account for 32% of suspended students. For over 30 years, research has consistently highlighted the disproportionately severe disciplinary practices used with Black male students.Consistent research demonstrates that students who are suspended or expelled tend to drop out of school and/or become incarcerated in a juvenile detention center. Black students may relate their racial-ethnic identity, such as their understanding of their race and ethnicity, to academic success. Moreover, their attitudes may result from the expectation of their teachers. It is imperative that advocates devoted to positive youth development intervene to this issue negatively affecting the well-being of Black youth. Under the mentorship of Caitlin Sayegh, Ph.D., postdoctoral fellow Tierra Ellis, Ph.D., has developed a 9-session group intervention called Black Youth M.A.T.T.E.R. (BYM), which aims to debunk mental health stigma, help children shift their cognitive distortions about education, and normalize their experiences through group activities, while introducing them to advocacy and self-empowerment. This intervention may decrease mental health symptoms, increase motivation to approach goal-oriented outcomes, and reverse internalized beliefs and attitudes which may foster more positive perceptions related to school.
Interpretation of breast MR images is a very time-consuming process and places a great burden on breast radiologists. This project aims to develop a technical solution that addresses this healthcare challenge by developing a system that is able to automatically interpret breast MR images in order to aid the radiologist in their diagnosis.
Multicenter, randomized, open label pilot clinical trial with two parallel arms aimed to compare the efficacy of Raltegravir (RAL) 1200mg QD vs Darunavir/Cobicistat (DRV-cb) 800-150mg QD both in combination with alafenamide/emtricitabine (TAF/FTC) in patients with Human Inmunodefficiency Virus (HIV) infection and CD4<200 cells/microL
The study aims to assess the prevalence of ventricular rhythmic disorder after an acute myocarditis in sportsmen. 50 patients with acute myocarditis, confirmed by MRI, will be assessed by ECG Holter and Treadmill stress test during a 1-year follow-up.
The aim of this study is to evaluate the insulin-like growth factor (IGF) axis involvement in the immune tumor microenvironment in ovarian cancer.
The femoro-popliteal arterial segment is one of the most frequent locations for atherosclerosis. Its management is mainly endovascular (standard and coated-balloon angioplasty, stenting). However, the structural features of the atherosclerotic disease in regards to patient's risk factors and past medical and surgical histories are not well studied. Furthermore, the histological analysis of the femoro-popliteal arterial segment is rare in the literature, and made difficult mostly because of the length of this segment. There is a clinical need for better understanding of atherosclerotic lesions in this location, with as further goal, a better management of this disease.
The aim of this pilot study is to evaluate the efficacy and safety of combined and simultaneous endoscopic variceal obliteration together with balloon occluded-retrograde transvenous obliteration (B-RTO) for the treatment of high-risk gastric varices
1. To validate the use of dynamic ultrasound for prediction of adhesions in women undergoing repeated cesarean section. 2. To detect the interobserver and intraobserver reliability of this method