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A Pilot Trial of Itraconazole Pharmacokinetics in Patients With Metastatic Breast Cancer

Breast Neoplasms Clinical Trial

Official title:
A Pilot Trial of Itraconazole Pharmacokinetics in Patients With Metastatic Breast Cancer

Clinical Trial Summary

Cancer cells need to be able to make new blood vessels in order to keep growing. This is called angiogenesis. In a laboratory setting, the drug itraconazole was shown to help stop the growth of new blood vessels (anti-angiogenesis). It is hoped that itraconazole will prevent new blood vessels from forming in humans too. The purpose of this study is to look at how the body processes and breaks down itraconazole (called pharmacokinetics). This study will also measure markers in your blood to see if itraconazole stops new blood vessels from forming. The safety of itraconazole will also be tested to see what effects (good and bad) it has on you and your breast cancer.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT00798135
Study type Interventional
Source Indiana University
Contact
Status Completed
Phase N/A
Start date November 2008
Completion date March 2012
View Details
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