Clinical Trial Details
— Status: Not yet recruiting
Administrative data
NCT number |
NCT05241925 |
Other study ID # |
Breast Cancer |
Secondary ID |
|
Status |
Not yet recruiting |
Phase |
N/A
|
First received |
|
Last updated |
|
Start date |
May 20, 2023 |
Est. completion date |
December 30, 2025 |
Study information
Verified date |
September 2022 |
Source |
University of Nove de Julho |
Contact |
Luciana Sampaio, PhD |
Phone |
+5511 996002075 |
Email |
lucianamalosa[@]gmail.com |
Is FDA regulated |
No |
Health authority |
|
Study type |
Interventional
|
Clinical Trial Summary
Cancer on the world stage remains a major public health problem and the most common type
among women.
Female breast cancer survivors often have multiple comorbidities such as diabetic, heart
disease, sarcopenia, arthritis, hypertension, and others. In addition to fatigue, reduced
functional capacity of the affected upper limb and decreased quality of life. The effects of
antineoplastic treatment associated with chronic diseases predispose the emergence of
cardiotoxicity, increasing the risk of developing cardiovascular diseases (CVD) and may lead
to a decline in quality of life. This situation is due to the adverse effects that
antineoplastic therapy exerts on the cardiovascular system.
According to the American Heart Association and American Cancer Society, physical exercise is
one of the strategies adopted to prevent and reduce the effects of anticancer therapy,
promoting effects on cardiovascular reserve5,6. Currently, although physical activity is
essential for cancer survivors, the most effective exercise strategies (intensity, duration
and type of exercise) to improve complications from breast cancer have not yet been defined.
The aim of the study is to investigate the effects of different types of physical training
associated with functional capacity and quality of life in women undergoing antineoplastic
treatment for breast cancer.
Description:
Cancer is a universal term used for a large group of diseases, characterized by the
disordered growth of cells beyond their usual limits, which can affect adjacent parts of the
body and/or spread to other organs and tissues. Breast cancer worldwide is a major public
health problem, being among all types of neoplasm the most common among women, regardless of
age and ethnicity.
Treatment for breast cancer may include surgery, radiation therapy, and systemic therapies
such as chemotherapy, hormone therapy, or biological therapy. A number of factors are
considered to determine the treatment and sequence of therapies. With advances in early
detection and treatment of cancer, the survival rate has increased in more developed
countries, reaching 85% in the first five years after diagnosis.
The survival of patients with breast cancer has increased, generating greater concern for the
individual's overall well-being. Chemotherapy treatments can cause short or long-term
cardiorespiratory limitations, reduced functional capacity and worse quality of life, making
daily activities difficult for these patients.