Breast Cancer Female Clinical Trial
Official title:
Effects of Continuous and Interval Physical Training Through the Intensity of the Incremental Shuttle Walk Test, on Functional Capacity and Quality of Life in Women With Malignant Breast Cancer During Chemotherapy Treatment
Cancer on the world stage remains a major public health problem and the most common type among women. Female breast cancer survivors often have multiple comorbidities such as diabetic, heart disease, sarcopenia, arthritis, hypertension, and others. In addition to fatigue, reduced functional capacity of the affected upper limb and decreased quality of life. The effects of antineoplastic treatment associated with chronic diseases predispose the emergence of cardiotoxicity, increasing the risk of developing cardiovascular diseases (CVD) and may lead to a decline in quality of life. This situation is due to the adverse effects that antineoplastic therapy exerts on the cardiovascular system. According to the American Heart Association and American Cancer Society, physical exercise is one of the strategies adopted to prevent and reduce the effects of anticancer therapy, promoting effects on cardiovascular reserve5,6. Currently, although physical activity is essential for cancer survivors, the most effective exercise strategies (intensity, duration and type of exercise) to improve complications from breast cancer have not yet been defined. The aim of the study is to investigate the effects of different types of physical training associated with functional capacity and quality of life in women undergoing antineoplastic treatment for breast cancer.
Status | Not yet recruiting |
Enrollment | 60 |
Est. completion date | December 30, 2025 |
Est. primary completion date | December 30, 2025 |
Accepts healthy volunteers | No |
Gender | Female |
Age group | 18 Years to 80 Years |
Eligibility | Inclusion Criteria: Diagnosis of confirmed breast cancer. Duration of adjuvant chemotherapy treatment. Undergoing surgery for breast cancer treatment. Exclusion Criteria: - neoplasm prior to breast cancer - heart disease; - musculoskeletal disorder; - respiratory disease; - uncontrolled arterial hypertension - factors that limit the performance of any of the assessments and/or training in the study. - Not having undergone chemotherapy or radiotherapy prior to the diagnosis of breast cancer. |
Country | Name | City | State |
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n/a |
Lead Sponsor | Collaborator |
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University of Nove de Julho |
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Distance Incremental Shuttle Walk Test (SWTI) | Distance walking meters | Distance Incremental Shuttle Walk Test (SWTI) | |
Primary | Maximum endurance test (1RM) | Kg | Maximum endurance test (1RM) | |
Secondary | Time Grocery Shelving Task Test | Seconds | Time Grocery Shelving Task Test | |
Secondary | European Organization for Research and Treatment of Cancer Core Quality of Life Questionnaire (EORTC QLQ-C30) | Score | European Organization for Research and Treatment of Cancer Core Quality of Life Questionnaire (EORTC QLQ-C30) | |
Secondary | Functional Assessment of Breast Cancer Therapy Questionnaire (FACT-B) | Score | Functional Assessment of Breast Cancer Therapy Questionnaire (FACT-B) | |
Secondary | Brief Fatigue Inventory Questionnaire (BFI) | Score | Brief Fatigue Inventory Questionnaire (BFI) |
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