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Bone Metastasis and Surgery in Breast Cancer

Breast Cancer Clinical Trial

Official title:
The Effect of Primary Surgery in Patients With Stage IV Breast Cancer With Bone Metastasis Only

Clinical Trial Summary

A registry trial evaluating resection of the primary breast tumor in women presenting with de novo stage IV breast cancer with bone metastasis only. Previous reports of carefully selected patients presenting with stage IV breast cancer suggest that surgery on the primary tumor may result in improved survival, but this remains unproven. The early results of our ongoing trial MF07-01 trial (a phase III randomized controlled trial of breast cancer women with distant metastases at presentation who receive loco-regional treatment for intact primary tumor compared with those who do not receive such treatment) showed that patients with bone metastasis only have a trend toward improved survival with initial surgery.

Clinical Trial Description

This registry trial evaluating resection of the primary breast tumor in women presenting with de novo stage IV breast cancer with bone metastasis only. Previous reports of carefully selected patients presenting with stage IV breast cancer suggest that surgery on the primary tumor may result in improved survival, but this remains unproven. The early results of our ongoing trial MF07-01 trial (a phase III randomized controlled trial of breast cancer women with distant metastases at presentation who receive loco-regional treatment for intact primary tumor compared with those who do not receive such treatment) showed that patients with bone metastasis only have a trend toward improved survival with initial surgery. Our goal is to test if primary surgery improves overall survival in bone only metastasis. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02125630
Study type Observational [Patient Registry]
Source Federation of Breast Diseases Societies
Contact
Status Completed
Phase
Start date January 2014
Completion date June 2019
View Details
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