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Biopsy clinical trials

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NCT ID: NCT06454513 Completed - Anesthesia Clinical Trials

Efficacy of Different Anesthesia Methods in Transbronchial Biopsy

EDAMTBB
Start date: June 1, 2020
Phase:
Study type: Observational

This study investigates the efficacy of different anesthesia methods (general anesthesia with laryngeal mask airway and local nebulized anesthesia) for transbronchial biopsy using an electronic bronchoscope. The study retrospectively analyzed cases of transbronchial biopsy performed at the Respiratory Endoscopy Center of Sichuan Provincial People's Hospital from June 5, 2020, to June 5, 2024. Data collected included age, gender, primary diagnosis, anesthesia method, biopsy method, operation time (excluding general anesthesia and laryngeal mask airway placement time), lesion location and size, pathological results, and follow-up status.

NCT ID: NCT05012527 Completed - Colonoscopy Clinical Trials

Retrospective Review of Gastrointestinal System Endoscopy Procedures

RRGIE
Start date: June 11, 2021
Phase:
Study type: Observational

The aim of the study is retrospectively evaluating all features of endoscopic and pathological diagnoses of cases who underwent upper and lower gastrointestinal endoscopy.

NCT ID: NCT04887597 Active, not recruiting - Psoriatic Arthritis Clinical Trials

EBIO - Enthesitis Biopsy Study

EBIO
Start date: March 18, 2019
Phase: Phase 4
Study type: Interventional

The purpose of this Phase IV study is to determine the effect of secukinumab on total immune cell numbers obtaines by entheseal biopsy in the inflamed human entheses in patients with Psoriatic Arthritis. This is a single arm, single centre, prospective, open label study with secukinumab.

NCT ID: NCT04809025 Recruiting - Stomach Neoplasms Clinical Trials

Comparation of Endoscopic Biopsy and Postoperative Specimen for the Molecular Diagnosis of Gastric Cancer

EBPS
Start date: May 24, 2021
Phase:
Study type: Observational

This study aims to test the hypothesis that the diagnosis for histological type, histological grade, LAUREN type, HER-2 expression, MSI/dMMR status, and EBV status in gastric cancer is at least as reliable when performed on endoscopic biopsy specimens as on surgical resection specimens.

NCT ID: NCT04553601 Recruiting - NSCLC Clinical Trials

Molecular Imaging Visualization of Tumor Heterogeneity in Non-small Cell Lung Cancer

Start date: October 1, 2019
Phase: N/A
Study type: Interventional

To assess the potential usefulness of radiogenomics for tumor driving genes heterogeneity in non-small cell lung cancer.

NCT ID: NCT04519554 Not yet recruiting - Biopsy Clinical Trials

Hysteroscopic Guided Endometrial Sampling: Prospective Comparison Between 5Fr and 7Fr Biopsy Forceps (HYSTEROBIO)

HYSTEROBIO
Start date: September 20, 2020
Phase: N/A
Study type: Interventional

Indication for hysteroscopic guided biopsy compared to blind biopsy have been little evaluated. However, this kind of biopsy is usually performed in many centre. They allow exploration of uterine cavity but also to perform guided biopsies on the most suspicious area. However, with 5Fr forceps, biopsy are often too small to conclude.

NCT ID: NCT03859804 Completed - Prostate Cancer Clinical Trials

Comparison of Pain Levels in Fusion Prostate Biopsy and Standard TRUS-Guided Biopsy

Start date: December 1, 2016
Phase: N/A
Study type: Interventional

The aim of this study was to compare the pain levels in transrectal ultrasound (TRUS)-guided standard 12-core prostate biopsy (SPB) and multiparametric prostate magnetic resonance imaging (MpMRI)-guided fusion prostate biopsy (FPB).

NCT ID: NCT02930616 Not yet recruiting - Clinical trials for Gastric Intestinal Metaplasia

A Comparison of pCLE Based Targeted Biopsy and WLE Based Standard Biopsy in Staging the Operative Link on Gastric Intestinal Metaplasia (OLGIM): A Randomized,Cross-over Study

Start date: October 2016
Phase: Phase 4
Study type: Interventional

Gastric intestinal metaplasia (GIM) is an important premalignant lesion for gastric cancer. Precisely surveillance of patients with GIM may result in early detection and improved prognosis. Though important, it is not necessary to recommend surveillance endoscopy for all patients with GIM, since the progression rate to gastric cancer within 10 years is only 1.8% in those patients.

NCT ID: NCT02851693 Withdrawn - Carcinoma Clinical Trials

Study of Imaging Characteristics OCT of Skin Lesions Requiring Biopsy / Resection

OCTSKIN
Start date: June 1, 2016
Phase: N/A
Study type: Interventional

The diagnosis of cutaneous lesions often involves the use of surgical and invasive procedures such as biopsy or excision in order to analyze the structure and appearance of the fabric pathologists. With recent advances in optical and electronic fields, considerable efforts were produced to build high-performance optical instruments, able to transcribe the internal structure of the skin with varying degrees of depth and variable resolution. The imagery is now an area of great interest for medical diagnosis: non-invasive, quick, and in real time. This area is booming and new optical instruments are created to eventually be able to offer a reliable alternative to invasive techniques. The optical properties of different tissues have been studied for several years by different research groups: the coefficient of light absorption by the tissue both in vivo and in vitro, the coefficient of light scattering or the index refractive were characterized in various tissues that make up the skin. Other studies have focused on melanoma detection by multispectral optical techniques, or via the technique of optical coherence tomography (OCT) performed on lesions suspicious for cancer, but without linking criteria between these two techniques. However, no study to date and to our knowledge has been able to demonstrate the different optical parameters obtained with OCT and can be directly connected to known and histopathological parameters commonly used in the diagnosis of lesions skin. This study aims to verify if it is possible to determine the parameters measured in OCT that would discriminate between benign and malignant lesions.

NCT ID: NCT02756975 Completed - Complication Clinical Trials

Prostate Core Needle Biopsy

Prostate
Start date: December 2014
Phase: N/A
Study type: Interventional

Prostate tissue biopsy is performed with either transrectal or transperineal approach. These two methods are usually based on tissue sampling with an ultrasound-guided core needle biopsy. Transperineal prostate biopsy can be done either with a conventional noncoaxial technique or with a coaxial technique. In conventional transperineal technique, biopsy needle is inserted repeatedly for each tissue sampling. Alternatively, a coaxial needle can be placed over the perineum; then, the direction of the biopsy can be changed by tilting the coaxial needle. In this prospective study, the investigators sought to compare the procedural time and the complication rate of coaxial technique with those of noncoaxial technique in transperineal prostate biopsy.