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Bariatric Surgery Candidate clinical trials

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NCT ID: NCT05387382 Completed - Clinical trials for Bariatric Surgery Candidate

Effects of Bariatric Surgery on Different Compositions of Trunk Fat and Mechanisms

Start date: May 20, 2022
Phase:
Study type: Observational [Patient Registry]

This is a prospective, single-center, observational study to explore effects of bariatric surgery on different compositions of trunk fat and mechanisms.

NCT ID: NCT05367479 Completed - Hypertension Clinical Trials

Antibiotics, Gastric Bypass, and the Microbiome

Start date: July 18, 2018
Phase: Phase 1
Study type: Interventional

This study randomizes patients to two commonly used peri-procedural antibiotics after gastric bypass with the pre and post-operative collection of stool samples, to identify significant differences in relative abundances of gut microbiota phyla, genera and species between the two antibiotic groups used. Gastric bypass may beneficially affect hypertension by altering the post-operative microbiome and specific antibiotics can further enhance the resolution rate by improving microbial diversity and richness.

NCT ID: NCT05353777 Completed - Clinical trials for Bariatric Surgery Candidate

Clinical Evaluation of the Levita Robotic Platform

Start date: May 15, 2021
Phase: N/A
Study type: Interventional

The purpose of this study is to evaluate the safety and feasibility of the Levita Robotic Platform (LRP) used with the Levita Magnetic Surgical System (MSS)

NCT ID: NCT05353426 Completed - Pain, Postoperative Clinical Trials

Paragastric Autonomic Blockade to Prevent Visceral Pain After Laparoscopic Sleeve Gastrectomy

PG-ANB
Start date: August 13, 2021
Phase: N/A
Study type: Interventional

Visceral pain (VP) following laparoscopic sleeve gastrectomy remains a substantial problem. VP is associated with autonomic symptoms, especially nausea and vomiting, and is unresponsive to traditional pain management algorithms aimed at alleviating somatic (incisional) pain. The present study was performed to evaluate the safety and effectiveness of laparoscopic paragastric autonomic neural blockade (PG-ANB) in managing the symptoms associated with VP following sleeve gastrectomy.

NCT ID: NCT05341414 Completed - Clinical trials for Bariatric Surgery Candidate

Trajectories of Resilience and Bariatric Surgery Outcomes

ECLAIRCIE
Start date: May 3, 2021
Phase:
Study type: Observational

A high prevalence of psychological trauma on one hand and of psychiatric disorders, such as depression, anxiety, suicide attempts, addictions, and eating disorders on the other hand, has been reported in patients with severe obesity seeking bariatric surgery. Some studies reported an increased prevalence of these psychiatric disorders after bariatric surgery, potentially related to weight regain. In this context, psychological resilience is a concept that brings together internal and external factors of adaptation, and whose clinical use facilitates interdisciplinary collaborative work. This research focuses on the association between resilience and success or failure of bariatric surgery in patients followed in the Specialized Obesity Center (CSO) of the Nancy University Hospital. The hypothesis is that psychological resilience before surgery promotes successful surgical treatment. This retrospective study is based on existing data from patients with severe obesity who have undergone bariatric surgery at the Nancy CSO. The main objective is to study 1) the resilience of patients with severe obesity, candidates for bariatric surgery, at the first assessment (T0), at the end of lifestyle/behavioral modifications program (T1) and at 2 years after bariatric surgery (T2), 2) the relationship between internal and external factors explaining resilience and final weight outcomes. The investigators are expected that non-resilient patients have more psychological vulnerabilities (psychopathology, negative life events, etc.), and have lower weight loss than resilient patients.

NCT ID: NCT05284695 Completed - Clinical trials for Bariatric Surgery Candidate

THE EFFICIENCY OF FASCIAL PLANE BLOCKS IN BARIATRIC SURGERY

Start date: January 1, 2019
Phase:
Study type: Observational

Bariatric surgery effectively produces weight loss and reduces obesity-related comorbidities. Although it is mostly performed with minimally invasive techniques, the patients may still suffer from moderate-to-severe pain immediately after surgery [1]. Opioids remain the first choice for multimodal analgesia in the treatment of postoperative pain. Providing analgesia after bariatric surgery might be challenging due to a high prevalence of obstructive sleep apnea syndrome and the increased sensitivity to respiratory depression triggered by opioid overuse after surgeryThe most common plane block techniques utilized during laparoscopic bariatric surgery are transversus abdominis plane block (TAP), rectus sheath block (RB), the erector spinae plane block (ESPB) and the external oblique intercostal block (EOI). In this study, we have evaluated the auxiliary benefit of these various techniques in reduction of the postoperative in bariatric surgery. patients who had laparoscopic bariatric surgery at VKV American Hospital between January 2019 and December 2021 were reviewed retrospectively.

NCT ID: NCT05189353 Completed - Clinical trials for Bariatric Surgery Candidate

The Importance of Ghrelin for Glucose Metabolism After Sleeve Gastrectomy

Start date: January 14, 2022
Phase: N/A
Study type: Interventional

The overall aim is to delineate the contribution of ghrelin to glucose tolerance after sleeve gastrectomy. The hypothesis is that decreased concentration of ghrelin after SG is of importance for improved insulin secretion and glucose tolerance seen after SG. The expectation is therefore that infusion of ghrelin will impair insulin secretion and glucose tolerance compared with a control day without ghrelin infusion.

NCT ID: NCT05087615 Completed - Clinical trials for Bariatric Surgery Candidate

Effects of Ondansetron, Metoclopramide and Granisetron on Perioperative Nausea and Vomiting in Patients Undergone Bariatric Surgery

PONV
Start date: March 1, 2021
Phase: Phase 3
Study type: Interventional

Post-operative nausea and vomiting (PONV) is one of the leading causes of patient morbidity after laparoscopic bariatric surgeries. A wide variety of complications related to PONV has been described, such as prolonged length of stay (LOS) in hospital, unnecessary readmissions, delay in oral intake, and bad experience for patients. Although several antiemetic regimens have been tried so far in different studies, the incidence of PONV is not significantly lowered, and it seems that it is impossible to totally eliminate it. On the other hand, the implementation of Enhanced Recovery After Surgery (ERAS) has greatly reduced the incidence of PONV and LOS. Therefore, a combination of ERAS and multiple antiemetic regimens is currently used to reduce the incidence of PONV. Nevertheless, the optimal regimen has not been found yet, and many trials are conducting to find out the best antiemetic regimen. In this randomized clinical trial, we compare four different combined and single regimens alongside the implementation of ERAS to show which regimen is more effective.

NCT ID: NCT05050968 Completed - Clinical trials for Bariatric Surgery Candidate

Physical Activity and Bariatric Surgery

ACTIBARIA
Start date: February 23, 2018
Phase: N/A
Study type: Interventional

Bariatric surgery indeed leads to significant weight loss, reduces mortality risk, obesity-associated comorbidities (Wolfe et al., 2016) and improves functional physical abilities (Herring et al., 2016). Because these benefits are related to decreased energy intake, the investigators aim to optimize them by combining them with supervised adapted physical activity practice. So, the aim of this clinical trial is to measure the effects of a physical training program on physical fitness, body composition and quality of life of obese women who have undergone bariatric surgery.

NCT ID: NCT05026125 Completed - Obesity Clinical Trials

Quality Assessment of Orotracheal Intubation Without Neuromuscular Blocking Agents in Obese Patients

OBEREM
Start date: January 13, 2022
Phase: Phase 4
Study type: Interventional

This study will assess the condition of orotracheal intubation in obese patients undergoing an elective bariatric surgery without the use of neuromuscular blocking agents. During the induction of general anesthesia, Propofol - Remifentanil combination will be used. The patients will be randomized in 2 groups with different doses of Remifentanil.