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Bariatric Surgery Candidate clinical trials

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NCT ID: NCT06464822 Recruiting - Clinical trials for Bariatric Surgery Candidate

Prospective Data on Bariatric Surgery Effect on IPSS and LUTS

Start date: January 1, 2008
Phase:
Study type: Observational

To establish a central database on clinical parameters for patients who has morbid obesity, which aiming at 1. to compare the results of those with or without receiving invasive bariatric treatment in Prince of Wales Hospital ( Multidiciplinary Clinic of Metabolic & Bariatric Surgery) and CUHK Medical Centre (Weight Management & Metabolic Surgery Clinic). 2. To audit and compare outcome between PWH, CUHK Medical Centre, and with other bariatric surgery centers in Hong Kong (Hong Kong Bariatric & Metabolic Surgery Registry) 3. To compare outcome with the regional/international center databse for benchmarking performance of HK bariatric surgery

NCT ID: NCT06452784 Recruiting - Clinical trials for Obstructive Sleep Apnea

Pre- and Postoperative Apnea-Hypopnea Index After Same-Day Discharge Bariatric Surgery

DAGBAR
Start date: May 31, 2024
Phase:
Study type: Observational

A recent development is same-day discharge in bariatric surgery, this seems to be safe if proper discharge criteria are used. However, yet there is no guideline for these discharge criteria, including for patients with (potential) Obstructive Sleep Apnea (OSA). To establish proper discharge criteria concerning OSA more information about (changes in) OSA during the first days after bariatric surgery is required. The aim of this study is to assess postoperative Apnea-Hypopnea Index (AHI) changes during the first and third night after Same-Day Discharge bariatric surgery in patients with potentially untreated OSA. Methods: Patients (n=60) will undergo a Home Sleep Apnea test , pre-operatively and during the first en third postoperative night after bariatric surgery to asses the AHI and sleep architecture.

NCT ID: NCT06432933 Recruiting - Obesity Clinical Trials

Comparison of Apnea-Hypopnea Index in Patients With or Without Preventive Oxygen Therapy After Bariatric Surgery

OXYBAR
Start date: April 9, 2024
Phase: N/A
Study type: Interventional

The best perioperative strategy for obstructive sleep apnea (OSA) in bariatric surgery remains unclear. A strategy is to monitor patients and administer preventive oxygen therapy during the first postoperative night. However it is unknown what if preventive oxygen therapy is necessary. The goal of this trial is to compare the Apnea-Hypopnea Index (AHI) in participants with or without preventive oxygen therapy. Methods: Participants are patients who underwent bariatric surgery without treated OSA and will be will be randomized into arm A or arm B: Arm A: First postoperative night in the hospital with preventive oxygen therapy (standard care), Arm B: First postoperative night in hospital without preventive oxygen therapy (intervention).

NCT ID: NCT06432088 Recruiting - Clinical trials for Bariatric Surgery Candidate

Safety and Feasibility of Liver Retraction With the Levita Magnetic Surgical System: Extended Magnetic Grasper Device

Start date: May 13, 2024
Phase: N/A
Study type: Interventional

The purpose of this study is to evaluate the safety and effectiveness of the Extended Magnetic Grasper Device in patients undergoing bariatric and/or hiatal hernia procedures, as a liver retractor grasping the liver and/or the tissue surrounding the crus of the diaphragm.

NCT ID: NCT06420479 Recruiting - Clinical trials for Cardiovascular Diseases

The Causal Effect of Bariatric Surgery on Cardiovascular Disease and Mortality

Start date: January 1, 2024
Phase:
Study type: Observational [Patient Registry]

The association between weight, and cardiovascular disease and mortality is well established, however, the causal effect of weight-loss in midlife on these outcomes is less clear. Bariatric surgery results in substantial weight-loss and is an ideal candidate to study the causal effects of weight-loss. The investigators propose a project that will use causal inference and machine learning methods to answer two important questions: 1. Is bariatric surgery effective for reducing cardiovascular disease and mortality, and if so, for who? 2. Which type of bariatric surgery (gastric bypass or sleeve gastrectomy) is most effective, and for who? The investigators will use data from various Swedish registers to identify individuals with obesity who are eligible for bariatric surgery. We will then compare cardiovascular and mortality outcomes among those undergoing different types of bariatric surgery with those receiving non-surgical obesity management using causal inference methods. The investigators will use causal forests and expert knowledge to estimate indiviual treatment effects, and identify the groups of patients who benefit the most from these surgeries.

NCT ID: NCT06372912 Recruiting - Clinical trials for Bariatric Surgery Candidate

Early Postoperative Complications in Patients Undergoing Bariatric Surgery

Start date: April 1, 2024
Phase:
Study type: Observational

This study examined immediate postoperative complications in patients undergoing various bariatric surgeries, aiming to evaluate the safety and efficacy of these interventions. Conducted at specialized high-volume bariatric surgery centers in Tijuana, Mexico. Predominantly female patients with severe obesity underwent procedures like sleeve gastrectomy and Roux-en-Y gastric bypass. Immediate complications were rare, occurring in only 0.38% of patients, with bleeding being the most common issue. Surgical reintervention within 48 hours was required in 0.33% of cases. The study's low complication rate suggests that surgeon expertise is crucial in minimizing risks and improving postoperative outcomes in bariatric surgery.

NCT ID: NCT06297928 Recruiting - Clinical trials for Bariatric Surgery Candidate

Metabolomics and Bariatric Surgery in Patients With Metabolically Unhealthy Obesity

Start date: January 1, 2024
Phase:
Study type: Observational

The goal of this observational study is to investigate metabolic changes in individuals undergoing bariatric surgery, specifically focusing on those with obesity and varying metabolic health statuses. The main questions it aims to answer are: - Can metabolic markers predict the transition from metabolically unhealthy obesity to metabolically healthy obesity after bariatric surgery? - How do metabolic profiles change in individuals with metabolically healthy obesity after bariatric surgery? - What are the metabolic differences between individuals with metabolically healthy and unhealthy obesity before and after bariatric surgery? Participants will undergo routine evaluations and blood tests before and after bariatric surgery. These tests will include assessments of metabolic health markers and sampling of blood plasma for metabolomic analysis. The study will study changes in metabolic profiles between individuals who transition to metabolically healthy obesity and those who remain metabolically unhealthy after surgery.

NCT ID: NCT06287931 Recruiting - Clinical trials for Bariatric Surgery Candidate

Probiotics for Gallstones in Post-bariatric Surgery Patients

Start date: January 1, 2024
Phase: N/A
Study type: Interventional

Obesity is an increasing epidemic worldwide and has a significant impact on human health and socioeconomics. Multiple studies have shown that bariatric surgery increases the risk of postoperative gallbladder stones. Contributing factors to gallstone formation include gallbladder motility and bile supersaturation due to rapid weight loss and cholesterol mobilization. At present, the prevention and treatment of gallbladder stones in obese patients after bariatric surgery are still controversial. In recent years, the study of ursodeoxycholic acid in preventing gallbladder stone formation after bariatric surgery has become a research hotspot. At the same time, other studies have shown that taking probiotics or digestive enzymes may improve gastrointestinal symptoms and improve quality of life after bariatric surgery. Therefore, the purpose of this study was to determine the ability of probiotics to prevent gallstone formation after bariatric surgery and to evaluate the impact of oral probiotics on quality of life in patients after bariatric surgery.

NCT ID: NCT06282094 Recruiting - Clinical trials for Bariatric Surgery Candidate

ViSiGi LUX Bariatric Sizing and Calibration System

Start date: January 26, 2024
Phase:
Study type: Observational

This study investigates the new ViSiGi LUX.

NCT ID: NCT06252558 Recruiting - Clinical trials for Bariatric Surgery Candidate

Symbiotic Use in Post-Bariatric Surgery Patients

Start date: January 8, 2024
Phase: N/A
Study type: Interventional

The purpose of this double blind, randomized control trial would be to test the efficacy of a once daily, multi strain symbiotic on gut health changes in weight loss surgery patients by testing stool samples prior to administration and then three months post administration of the symbiotic to monitor any changes in bacteria in the stool samples. Study participants will also complete a survey that evaluates their bowel habits, stool consistency, and gastrointestinal related symptoms.