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Arthropathy of Knee clinical trials

View clinical trials related to Arthropathy of Knee.

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NCT ID: NCT04291833 Completed - Knee Osteoarthritis Clinical Trials

Prospective, Assessment of Vitamin D and Calcium Supplementation, Improvement of Nutritional Status and Preoperative Rehabilitation in Patients Before Knee Arthroplasty.

Start date: January 1, 2015
Phase: N/A
Study type: Interventional

Prospective randomized study of 150 patients qualified for knee arthroplasty between 2015 and 2017. Patients were randomized into 3 groups receiving vitamin D and calcium supplementation, increased protein supply and preoperative rehabilitation, respectively. Following factors were analyzed: changes in vitamin D3, calcium, total protein, albumin and CRP levels during preparation for surgery, nutritional status on the Subjective Global Assessment (SGA) scale, osteoporosis risk assessment according to the Osteoporosis Risk SCORE, level of pain felt on the scale VAS and the number of analgesics used, the result of the Duke Activity Status Index, the result of the following scales: Cardiac Risk Index for Orthopedic Surgery (Lee), Knee injury and Osteoarthritis Outcome Score (KOOS), Fear Avoidance Beliefs Questionnaire (FABQ) about Physical Activity, The Quality of Life Scale (QOLS). Additionally, the occurrence of perioperative complications was analyzed (e.g. venous thrombosis and pulmonary embolism, wound or joint infection, excessive bleeding, loosening of the implant, bone fracture or fracture, pain).

NCT ID: NCT04118023 Completed - Knee Injuries Clinical Trials

7T MRI to Evaluate Cartilage Defects in the Knee

Start date: October 7, 2019
Phase:
Study type: Observational

The investigators propose to prospectively evaluate the accuracy of a novel 7-Tesla (7T) knee MRI protocol for the detection and grading of cartilage lesions in the knee, which is a significant limitation of current MRI techniques.

NCT ID: NCT04099355 Withdrawn - Arthropathy of Knee Clinical Trials

Investigating the Effect of Dronabinol on Post-surgical Pain

Start date: September 1, 2025
Phase: Early Phase 1
Study type: Interventional

This study is designed to investigate the effect of dronabinol on post operative pain in patients undergoing total knee replacement (for their own clinical care).

NCT ID: NCT04084912 Not yet recruiting - Arthropathy of Knee Clinical Trials

Effect of Preoperative Steroid in Total Knee Arthroplasty

Start date: January 1, 2020
Phase: Phase 3
Study type: Interventional

Detect the effect of preoperative steroid injection in total knee arthroplasty on post operative: 1. pain 2. oedema 3. nausea and vomiting 4. quadriceps power 5. knee flexion 6. wound complications

NCT ID: NCT04010266 Completed - Pain, Postoperative Clinical Trials

RelieVRx for Total Knee Arthroplasty (TKA) for the Reduction of Acute Postoperative Pain and Opioid Use

Start date: March 1, 2021
Phase: N/A
Study type: Interventional

This is a single-center, prospective, randomized, controlled study of the appliedVR RelieVRx headset in subjects undergoing Total Knee Arthroplasty (TKA). This study will evaluate two primary endpoints - effectiveness of a single use of RelieVRx in the reduction of acute postoperative pain by 20%; and overall effectiveness of RelieVRx as an opioid-sparing intervention, where opioid consumption is reduced by at least 20% over a 90-day postoperative period in the interventional, standard of care (SOC) plus RelieVRx group compared to the control, SOC group.

NCT ID: NCT03958370 Recruiting - Arthropathy of Knee Clinical Trials

Validation of Consumer Activity Monitors in Postoperative Total Arthroplasty Patients

Start date: January 8, 2019
Phase:
Study type: Observational

Mobilization and rehabilitation are essential components of a successful functional recovery following total hip and knee arthroplasties. Currently, we have no good measure of how mobile patients are after their surgery. Recent technological advances in personal activity monitors, such as the Fitbit, might provide medical providers and patients the opportunity to more objectively monitor their postoperative mobility and recovery course. However, these consumer activity monitors have yet to be validated in terms of their accuracy and utility for monitoring mobility in the immediate postoperative setting in arthroplasty patients. Our goal is to validate one of the most popular consumer activity monitors, the Fitbit Zip, in the postoperative total joint arthroplasty patient population.

NCT ID: NCT03954912 Completed - Clinical trials for Osteoarthritis, Knee

Comparative Outcomes Between Image-based Versus Imageless Robot-assisted Unicondylar Knee Arthroplasty

Start date: June 1, 2015
Phase: N/A
Study type: Interventional

This prospective cohort study was conducted with the aim of comparing relevant clinical outcomes which included intra (surgical time and blood loss), post-operative outcomes (range of motion, function, complications and revisions) and return to activity between imageless and image-based surgical system in medial unicondylar knee arthroplasty

NCT ID: NCT03940651 Terminated - Anesthesia Clinical Trials

Cardiac and Renal Biomarkers in Arthroplasty Surgery

Start date: September 4, 2019
Phase: Phase 4
Study type: Interventional

The investigators will compare the effect of spinal anesthesia to general anesthesia on the level of high sensitivity cardiac biomarkers in patients undergoing hip or knee arthroplasty. The investigators will also measure renal biomarkers in urine to evaluate kidney injury in the postoperative period.

NCT ID: NCT03921034 Completed - Anesthesia Clinical Trials

IPACK Nerve Block for Total Knee Arthroplasty

Start date: November 17, 2016
Phase: Phase 4
Study type: Interventional

Double-blind, randomized controlled clinical trial to test the efficacy of IPACK on postoperative opioid consumption, patient satisfaction, pain scores, mobility, and several other secondary outcomes in adults undergoing primary unilateral TKA. Enrolled patients will be randomized to either continuous ACB with IPACK or to continuous ACB with sham subcutaneous saline injection. Outcomes assessors and patients will be blinded to the intervention.

NCT ID: NCT03896282 Completed - Arthropathy of Knee Clinical Trials

Outpatient Total Joint Arthroplasty in Dedicated Daycare Facility vs Standard Patient Ward

Start date: August 1, 2017
Phase: N/A
Study type: Interventional

The purpose of this single center randomized controlled trial (RCT) is to investigate whether outpatient arthroplasty surgery in a dedicated daycare facility will improve discharge on day of surgery, as opposed to surgery followed by subsequent stay in the ward and also same day discharge, without compromizing safety and outcome.