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Appendicitis clinical trials

View clinical trials related to Appendicitis.

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NCT ID: NCT06363318 Completed - Appendicitis Acute Clinical Trials

Comparison of Open and Laparoscopic Appendectomy in Pediatric Population

Appendicitis
Start date: July 1, 2019
Phase: N/A
Study type: Interventional

Introduction: In the era of minimally invasive surgery, changing trends are towards laparoscopic surgery, first introduced in 1983. Now the preferred operation for children with appendicitis, laparoscopic appendectomy is associated with a reduced risk of wound infection, less postoperative pain and shorter hospital stay as compared to open appendectomy. Objectives: To compare the outcome of open and laparoscopic appendectomy in children presenting with appendicitis in terms of operative time, postoperative pain, wound infection and hospital stay.

NCT ID: NCT06344897 Completed - Surgery Clinical Trials

The Effect of Kinesio Taping in Pediatric Surgery

Start date: February 25, 2024
Phase: N/A
Study type: Interventional

This study was planned to determine the effect of kinesio taping (KT) applied to the abdominal area after surgery on pain and gas output in children aged 6-12 years who had open appendicitis surgery.

NCT ID: NCT06064331 Completed - Appendicitis Clinical Trials

Effect of Intravenous Lignocaine Infusion on Intraoperative End Tidal Desflurane Concentration Requirements

Start date: January 21, 2021
Phase: N/A
Study type: Interventional

Lignocaine is a local anaesthetic that is widely used in all medical and surgical fields. Many clinical studies have shown that intravenous (IV) lignocaine given in the perioperative period was safe, reduced airway complications, obtunds cough reflex, reduce sore throat, pain, opioid consumption, nausea, length of hospital stay. Multiple animal studies have shown that IV lignocaine was able to lower anaesthetic gas requirements. Desflurane is an anaesthetic gas that has a rapid onset and offset of action. This study aims to evaluate the effect of IV lignocaine infusion on desflurane requirements. Hypothesis of the study is that IV lignocaine infusion reduces desflurane requirements.

NCT ID: NCT05840419 Completed - Surgery Clinical Trials

Retrospective Comparison Between AirSeal® and Standard Insufflation in Appendicular Peritonitis

APPAS
Start date: January 1, 2022
Phase:
Study type: Observational

The AirSeal System Valve-less Trocar is known to decrease postoperative pain, consumption of analgesics, operating time, and length of stay in adults during robotic and laparoscopic procedures. The investigators would like to know if these allegations also apply to children.

NCT ID: NCT05759351 Completed - Pregnancy Related Clinical Trials

Appendectomy During Pregnancy and Child Development

Start date: January 1, 2006
Phase:
Study type: Observational

Maternal acute appendicitis during pregnancy is the most common abdominal surgical emergency. Long-term neurodevelopmental issues were scarcely reported. The aim of the study is to investigate the impact of appendicitis and appendectomy during pregnancy in general anesthesia on the cognitive and psychomotor development of children.

NCT ID: NCT05651360 Completed - Acute Pain Clinical Trials

Diagnostic Performance of Low-Dose CT for Acute Abdominal Conditions

DETECT_Acute
Start date: December 7, 2022
Phase:
Study type: Observational

The goal of this non-inferiority observational study is to assess the diagnostic performance of low-dose CT with deep learning image reconstruction (DLIR) in adult participants with acute abdominal conditions. The main research question is: • Can low-dose CT with DLIR achieve the same diagnostic performance as standard CT for the diagnosis of acute abdominal conditions. Participants will be examined with an additional low-dose CT directly after the standard CT. Participant will be their own controls.

NCT ID: NCT05571566 Completed - Appendicitis Clinical Trials

The Impact of a Patient Education Tool for Appendicitis

Start date: December 3, 2019
Phase: N/A
Study type: Interventional

Hypothesis/Study question (brief introduction of the question studied; about 5 lines) Appendicitis is the most common acute surgical admission to the pediatric surgery service at the MCH. The need for surgery can provoke anxieties for patients. Patient education materials are meant to improve knowledge, set expectations, and improve the overall hospital experience for patients and their families, and are already being widely implemented for elective surgeries in the context of ERAS pathways. This study aims to develop an effective patient and family education tool, with the goal of improving patient education and satisfaction with care in the emergency surgery setting. Study objectives 1. Utilize evidence-based methods to evaluate the success of implementation of a patient and family-centered education tool for appendicitis. 2. Develop and validate a pre- and post- education patient satisfaction and experience survey in the realm of pediatric surgery. 3. Inform the development of the education tool and survey through multidisciplinary and patient/family input. 4. Implement a patient/family-centered education tool in an emergency surgical setting.

NCT ID: NCT05470517 Completed - Acute Appendicitis Clinical Trials

Antibiotic Instillation in Appendicitis

Start date: January 5, 2023
Phase: Phase 2
Study type: Interventional

Appendicitis (inflammation of the wall of the appendix, causing pain and tenderness in the abdomen) has a range of severity that goes from simple to complicated. Complicated appendicitis may present with infected fluid inside of the abdomen or a perforation or hole in the intestines. This research is being done to determine if placing an antibiotic solution in the abdomen at the time the appendix is removed is a safe procedure in patients between the ages of 3 and 18 years old with findings of complicated appendicitis. Johns Hopkins All Children's Hospital (JHACH)'s current standard of care for patients with complicated appendicitis includes suctioning the infected fluid out of the abdomen at the time the appendix is removed. As part of this study, the investigators would like to see if patients with complicated appendicitis will benefit from routine care plus leaving an antibiotic solution inside the abdomen, after fully suctioning the infected fluid out of the abdomen.

NCT ID: NCT05434988 Completed - Obesity Clinical Trials

Outcome and Quality of Life in Obese Patients Underwent Laparoscopic vs. Open Appendectomy

Start date: March 1, 2020
Phase:
Study type: Observational

Although obesity is a popular reason for choosing laparoscopic appendectomy (LA) versus open appendectomy (OA), however, the question of whether there is a difference remains. The goal of the present study is to investigate if there is a difference between OA and LA in obese patients. In the present study, Fifty-eight obese patients were diagnosed with acute appendicitis according to Alvarado score at the department of surgery at Suez Canal university hospitals from March 2020 till August 2021were included. The study participants were assigned to two groups, after their approval: LA and OA. The investigators hypothesized that evaluating the Outcome and Quality of life of laparoscopic appendectomy for the obese patients would be a potential step for standardization of the laparoscopic approach for obese patients who are arranged for appendectomy.

NCT ID: NCT05430633 Completed - Appendicitis Clinical Trials

Laparoscopic Versus Open Appendectomy in Pregnancy

Start date: November 1, 2021
Phase:
Study type: Observational

The aim of this retrospective trial is to compare surgical and pregnancy outcomes of pregnant patients who underwent laparoscopic or open appendectomy for acute appendicitis.