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Aneurysm, Dissecting clinical trials

View clinical trials related to Aneurysm, Dissecting.

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NCT ID: NCT05745428 Active, not recruiting - Aortic Dissection Clinical Trials

Shear Stress Endothelial/Hemodynamics in Aortic Dissection and Endothelial Shear Stress-biological Profile

HADES-BP
Start date: April 10, 2022
Phase:
Study type: Observational

Aortic dissection (AD) is a clinical condition belonging to the broader spectrum of Acute Aortic Syndromes, with high morbidity and mortality and characterised by the sudden formation of a breach within the tonaca intima of the aortic wall, from which the so-called false lumen originates.The most common risk factor for AD is hypertension, present in more than 70% of. Imaging, biomarkers and genetic predisposition are critical in confirming a suspected diagnosis and in determining the appropriate intervention for each patient. Specific features influencing management decisions are the presence of rupture, extent of dissection, origin of true or false lumen vessels and signs of organ ischaemia.

NCT ID: NCT05405790 Active, not recruiting - Aortic Dissection Clinical Trials

Antibiotic Prophylaxis for TEVAR

Start date: January 1, 2022
Phase:
Study type: Observational

The infection rate of thoracic endovascular aortic repair (TEVAR) is unknown due to a lack of epidemiological data. The rate currently available comes from researches conducted decades ago, when open surgery was the standard of care. Because of the potentially fatal consequences of a stent graft infection in the thoracic aorta, the investigators tend to prescribe antibiotic prophylaxis for at least three days. In this study, the investigators are going to collect data on patients receiving TEVAR in the past five years and provide the following information: a. the infection rate (MAGIC classification), b. the rate of fever, c. the results of the lab tests, such as the WBC count and C-reaction protein. d. risk factors associated with infection and fever.

NCT ID: NCT05030740 Active, not recruiting - Clinical trials for Dissection of Thoracic Aorta

French Assessment of the Relay Plus and Relay NBS Plus Thoracic Stent-Graft

Start date: December 18, 2014
Phase:
Study type: Observational

Stent treatment of thoracic aortic pathologies, including aneurysms, pseudo-aneurysms, dissections, intramural hematomas, penetrating ulcers and ruptures of the isthmus, seems to provide a likely benefit compared to surgery in terms of surgical mortality and severe morbidity. However, the data concerning the long-term fate of these stents are insufficient. For this reason, the French National Health Authority (HAS) requests a 5-year follow-up in relation to the renewal of insurance reimbursement for these stent-grafts. Therefore, this long-term observational study has been set up.

NCT ID: NCT04831073 Active, not recruiting - Clinical trials for Type A Aortic Dissection

European Registry of Type A Aortic Dissection

ERTAAD
Start date: February 28, 2023
Phase:
Study type: Observational

Acute Stanford type A aortic dissection (TAAD) is a life-threatening condition. Surgery is usually performed as a salvage procedure and is associated with significant postoperative early mortality and morbidity. Understanding the patient's conditions and treatment strategies which are associated with these adverse events is essential for an appropriate management of acute TAAD.

NCT ID: NCT03748602 Active, not recruiting - Clinical trials for Neurogenic Thoracic Outlet Syndrome

Surgical Thoracic Outlet Decompression for Neurogenic Thoracic Outlet Syndrome

STOPNTOS
Start date: October 1, 2018
Phase: N/A
Study type: Interventional

This study will determine the value of TOD (first rib resection with partial scalenectomy and neurolysis) on functionality and quality of life for patients with neurogenic thoracic outlet syndrome. This will be done by randomizing patients into surgery or conservative therapy (physiotherapy and pain relief).

NCT ID: NCT03735472 Active, not recruiting - Clinical trials for Aortic Arch; Aneurysm, Dissecting

Study of the Thoraflex™ Hybrid Device for the Treatment of Aneurysm/Dissection of the Descending Thoracic Aorta

Start date: April 2016
Phase:
Study type: Observational

The purpose of this national observational study is to evaluate the Thoraflex™ Hybrid vascular prosthesis in the replacement of the aortic arch and the treatment of aneurysm/dissection of the descending thoracic aorta in relation to morbidity-mortality, visceral malperfusions, neurological and renal complications, endoleak and evolution of the aortic thoracic stent over time.

NCT ID: NCT03369977 Active, not recruiting - Clinical trials for Type A Aortic Dissection

BioGlue as an Adjunct for Structural Repair and Hemostasis in Chinese Acute Type A Aortic Dissections Patients

CHINA
Start date: November 1, 2017
Phase: N/A
Study type: Interventional

A multi-center, randomized, controlled clinical trial is designed to investigate the safety and efficacy of BioGlue as an adjunct for structural repair and hemostasis to traditional surgical repair in Chinese subject with Acute type A aortic dissections.

NCT ID: NCT02364791 Active, not recruiting - Clinical trials for Thoracic Surgery Lung

A Phase II Prospective, Single Blinded, Randomized Trial of Hemopatch Compared to Standard Techniques to Achieve Air Leak Control After Complex Thoracic Surgical Procedures

Hemopatch
Start date: February 2015
Phase: Phase 2
Study type: Interventional

The purpose of this study is to explore whether the addition of Hemopatch to standard care can reduce prolonged air leaks and shorten the use of air drainage tube after surgery in thoracic lung surgery patients at high risk for prolonged air leaks.

NCT ID: NCT02188069 Active, not recruiting - Clinical trials for Spontaneous Coronary Artery Dissection

Canadian SCAD Study

Start date: June 2014
Phase:
Study type: Observational [Patient Registry]

SCAD (Spontaneous coronary artery dissection - tear in the arterial wall that is not related to trauma) is an under-diagnosed and poorly understood condition that mostly affects young women without common cardiovascular risk factors, and can result in heart attack and death. This observational study is designed to capture the disease's natural history and predisposing arteriopathies (medical conditions resulting in changes in the arteries), treatment strategies, long-term cardiovascular outcomes. It will also improve the diagnosis of SCAD on coronary angiography by participating clinicians, and provide guidance on investigating predisposing conditions.

NCT ID: NCT00657969 Active, not recruiting - Stroke Clinical Trials

Looking For Genetic and Environmental Risk Factors and Therapeutic Aspects in Cervical Artery Dissections

CADISP
Start date: July 2005
Phase: N/A
Study type: Observational

The main purpose of this study is to look for genetic and environmental risk factors of cervical artery dissections, a major cause of ischemic stroke in young adults, in a large multicenter case-control trial