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Anesthesia, Local clinical trials

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NCT ID: NCT04204343 Completed - Anesthesia, Local Clinical Trials

Comparing Analgesic Effects of Caudal and Erector Spinae Plane Blocks in Pediatrics Undergoing Upper Abdominal Surgery

Start date: January 1, 2019
Phase: N/A
Study type: Interventional

Upper abdominal surgeries are painful and pediatric patients who undergo these operations require effective postoperative pain control. Epidural and caudal blocks are considered to be the gold standard regional analgesia techniques. Currently, ultrasound guidance is commonly used for caudal block performances to demonstrate the cannula placement and the deposition of local anesthetic. Additionally, erector spinae plane block can be a safer alternative for blocking the similar dermatomes. In this study, the aim is to compare postoperative analgesic effects of these two ultrasound-guided techniques in pediatric patients. The primary outcome of this study is the follow-up of FLACC/VAS pain scores. Secondary outcomes are time to first analgesic requirement, number of patients who require rescue analgesic, possible side effects, time to first mobilization, length of hospital stay and chronic pain due to incision after 2 months.

NCT ID: NCT04180943 Completed - Anesthesia, Local Clinical Trials

Liposomal Bupivacaine Versus Bupivacaine for for Postoperative Pain Control in Shoulder Surgery

Start date: December 13, 2019
Phase: Phase 4
Study type: Interventional

This is a randomized, single blinded clinical trial whose purpose is to assess the impact of liposomal bupivacaine (LB) in a single shot interscalene nerve block compared with standard bupivacaine (same dose) in a single shot interscalene nerve block in terms of postoperative pain control. Specifically, outpatient pain scores,use of postoperative pain medicine and patient-reported functional outcomes after shoulder arthroplasty surgery will be evaluated.

NCT ID: NCT04019834 Completed - Breast Cancer Clinical Trials

Preoperative Regional Nerve Block for Acute and Chronic Post-Operative Pain Following Mastectomy

RELIEF
Start date: July 6, 2020
Phase: Early Phase 1
Study type: Interventional

The purpose of this study is to see if pre-operative regional nerve blocks compared to a placebo nerve block can decrease chronic post mastectomy pain, immediate postoperative pain and postoperative narcotic consumption.

NCT ID: NCT03956797 Completed - Clinical trials for Diabetic Retinopathy

Long Term Safety of Cooling Anesthesia for Intravitreal Injection

COOL-2
Start date: April 15, 2019
Phase: N/A
Study type: Interventional

The purpose of this clinical study is to evaluate the long term safety and efficacy of cooling anesthesia application to the eye as anesthesia for intravitreal injection using a novel cooling anesthesia device.

NCT ID: NCT03921190 Completed - Anesthesia, Local Clinical Trials

Should Maxillary Buccal Infiltration Anesthesia be Given in a Closed Mouth Technique?

Start date: April 29, 2019
Phase: N/A
Study type: Interventional

To study the patients' and dentists' perception of receiving/ administering maxillary buccal infiltration anesthesia using an open or closed mouth techniques

NCT ID: NCT03911648 Completed - Anesthesia, Local Clinical Trials

Analgesic Efficacy of Lidocaine Plus Bupivacaine Versus Bupivacaine Alone Caudally

Start date: July 1, 2018
Phase:
Study type: Observational

Optimal analgesia following ambulatory surgery is an important matter for patient satisfaction and it reduces unnecessary hospital admissions. This study investigated whether caudal block with different combinations of local anesthetics can alter postoperative pain scores and additional rescue analgesic use. The investigators also aim to determine the side effects of these technique such as nausea, vomiting, bradycardia, hypotension, respiratory depression, length of hospital stay, first micturition or mobilization times, surgical and anesthetic complications.

NCT ID: NCT03878888 Completed - Surgery Clinical Trials

Exparel Use in Bilateral TAP Blocks for Postoperative Pain Control

Start date: January 15, 2019
Phase: Phase 4
Study type: Interventional

To determine if Exparel (Liposomal Bupivacaine, an FDA approved drug) use in ultrasound guided Transversus Abdominis Plane (TAP) blocks may reduce opioid requirement use postoperatively, reduce pain scores postoperatively, reduce incidence of nausea in the postop period, and decrease length of hospital stay

NCT ID: NCT03869801 Completed - Postoperative Pain Clinical Trials

Comparion of Erector Spinae Plane Block and Quadratus Lumborum Block in Laparoskopic Cholecystectomy

Start date: March 15, 2019
Phase: N/A
Study type: Interventional

Erector Spinae Plane Block is a newly defined regional anesthesia technique. Its use for many indications has been identified by case reports in the literature. As the investigators have considered that erector spinae plane block could be efficacious for providing postoperative analgesia in laparoscopic cholecystectomy, the investigators have implemented the application of this blockade into practice at the clinic.Quadratus Lumborum block (QLB) type 2 is another regional anesthesia technic used for postoperative analgesia in laparoscopic cholecystectomy. Main purpose of this study is to compare the analgesic effect of ultrasound-guided erector spinae block and QLB in laparoscopic cholecystectomy.

NCT ID: NCT03841409 Completed - Pharmacokinetics Clinical Trials

Peak Plasma Levels of Bupivacaine After an Erector Spinae Block (ESP)

Start date: June 14, 2019
Phase:
Study type: Observational

The primary objective of the study is to measure plasma levels of bupivacaine following erector spinae (ESP) regional block in patients undergoing mastectomy.

NCT ID: NCT03807505 Completed - Anesthesia, Local Clinical Trials

Erector Spinae Plane Versus Interscalene Blocks for Shoulder Surgery

Start date: June 13, 2019
Phase: N/A
Study type: Interventional

The goal of this study is the evaluation of erector spinae plane (ESP) blocks as an alternative to interscalene brachial plexus nerve blocks for rotator cuff repair and total shoulder arthroplasty procedures. Currently, single shot interscalene nerve blocks are performed for rotator cuff repair surgeries, and interscalene nerve catheters are placed for total shoulder arthroplasty surgeries. Erector spinae plane blocks are commonly used as part of the anesthetic plan for other surgeries, but less so for shoulder surgeries. The investigators would like to study whether an ESP block can provide similar pain control compared to an interscalene nerve block, with less risk of upper extremity motor block and phrenic nerve block.