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Anesthesia, Local clinical trials

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NCT ID: NCT03790540 Completed - Anesthesia, Local Clinical Trials

Pain Assessment During Mandibular Nerve Block Injection With the Aid of Dental Vibe Tool in Pediatric Dental Patients

Start date: December 1, 2018
Phase: Phase 2
Study type: Interventional

The purpose of this study is to valuate the effectiveness of DentalVibe(DV) tool in pain reduction during local anesthetic injection compared to traditional injection without aid of DentalVibe in pediatric patients.

NCT ID: NCT03780790 Completed - Anesthesia, Local Clinical Trials

Comparing Analgesic Effects of Three Ultrasound Guided Regional Anesthetic Techniques in Pediatrics

Start date: December 28, 2018
Phase: N/A
Study type: Interventional

This study evaluates analgesic effects of ultrasound-guided (USG) regional anesthetic techniques; caudal block , transversus abdominis plane (TAP) block and quadratus lumborum block (QLB) by comparing postoperative pain scores [ Face, Legs, Activity, Cry, Consolabilty(FLACC) and Visual Analogue Scale (VAS)], first analgesic requirement time and total analgesic consumption in pediatrics undergoing lower abdominal surgery. We also aim to observe the side effects of these techniques such as nausea, vomiting, bradycardia, hypotension, respiratory depression.

NCT ID: NCT03779568 Completed - Anesthesia, Local Clinical Trials

ED50 and ED95 of Isobaric Bupivacaine for Post-Partum Bilateral Tubal Ligation

Start date: February 25, 2019
Phase: N/A
Study type: Interventional

Spinal anesthesia is one of the preferred anesthetic techniques for post-partum bilateral tubal ligation (PBTL). Bupivacaine is the most commonly used local anesthetic for neuraxial anesthesia for post-partum tubal ligation. Typically, hyperbaric bupivacaine would be injected into the spinal (intrathecal) space via a spinal needle; however, ongoing medication shortages have resulted in limited availability on a local and national level. One proposed alternative is isobaric bupivacaine; however, studies investigating its use for post-partum bilateral tubal ligation are limited. The purpose of this prospective study is to determine the minimal effective dose (ED50 and ED95) of isobaric bupivacaine for adequate anesthesia during post-partum tubal ligation after vaginal delivery.

NCT ID: NCT03761329 Completed - Surgery Clinical Trials

Bier's Block Versus Mini-bier's Block in Patients Undergoing Hand Surgery

Start date: November 12, 2018
Phase: N/A
Study type: Interventional

By means of an observer-blinded, randomized controlled trial, the analgesic efficacy of an upper-arm Bier's block and a forearm mini-Bier's block will be investigated in patients undergoing hand surgery. The hypothesis is that there is no difference between the two types of anesthetic techniques with respect to the analgesic efficacy.

NCT ID: NCT03753594 Completed - Anesthesia, Local Clinical Trials

Changes of Regional Tissue Oxygenation Saturation After Successful Femoral Nerve Block

Start date: November 30, 2018
Phase:
Study type: Observational

Regional tissue oxygenation saturation has been shown to increase in innervated regions after sympathetic block. The aim of this prospective observational study was to evaluate the changes of regional tissue oxygenation saturation by near-infrared spectroscopy after successful femoral nerve block with ropivacaine and determine whether the changes of regional tissue oxygenation saturation can be affected by the concentration of ropivacaine.

NCT ID: NCT03744923 Completed - Anesthesia, Local Clinical Trials

Quadratus Lumborum Block (Transmuscular Approach) VS. TransversusAbdominus Plane Block(Unilateral Posterior Approach) for Perioperative Analgesia in Patients Undergoing Flank Incision Surgeries.

Start date: November 20, 2018
Phase: N/A
Study type: Interventional

Severe perioperative pain experienced after surgical procedures performed by flank incision is mainly related to incision of many muscles. Postoperative pain affects patient comfort, satisfaction, prolongs the duration of hospital stay and increases post-procedure complications. This study is designed to compare the success rate of Unilateral Ultrasound Guided Transmuscular Quadratus Lumborum Block with Unilateral posterior Ultrasound Guided TransversusAbdominus Plane block in providing perioperative analgesia in Patients undergoing Flank Incision surgeries in the Urosurgery Theater at KasrAlainy University Hospitals.

NCT ID: NCT03740386 Completed - Anesthesia, Local Clinical Trials

Phentolamine Mesylate as a Reversal of Local Anesthesics

Start date: January 1, 2016
Phase: N/A
Study type: Interventional

Oraverse © (Phentolamine mesylate) is a product designed to reverse the effect of local anesthetics used in dentistry. Its main objective is to reduce the postoperative period during which the patient suffers from the lack of sensitivity in the perioral soft tissues, it is an obvious discomfort, a difficulty to speak or eat, and sometimes a risk of self-injury in the lips and / or tongue . The product was approved by the FDA in 2008 although the introduction in Spain has not occurred until December 2015. There are numerous studies that support its use, its effectiveness and safety, although none of the Spanish population, who have not yet had the opportunity to experience it.

NCT ID: NCT03732287 Completed - Clinical trials for Diabetic Macular Edema

Cooling Anesthesia for Intravitreal Injection

COOL-1
Start date: November 30, 2018
Phase: Phase 1/Phase 2
Study type: Interventional

The purpose of this clinical study is to evaluate the safety and efficacy of cooling anesthesia application to the eye as anesthesia for intravitreal injection using a novel cooling anesthesia device and determine the effects of temperature and duration of application on subjective pain after intravitreal injection.

NCT ID: NCT03721081 Completed - Anesthesia, Local Clinical Trials

Local Anesthesia for Pediatric Cochlear Implant

Start date: August 1, 2014
Phase: Phase 4
Study type: Interventional

Propofol with remifentanil provides good operative conditions for pediatric cochlear implant (CI); however, large doses of remifentanil usually result in postoperative hyperalgesia and increase postoperative pain. Local anesthesia (LA) is commonly used as an adjunct to general anesthesia in children; however, otologists are usually reluctant in the use of LA as it can cause abolishment of the electrical stapedial reflex threshold (ESRT).

NCT ID: NCT03713762 Completed - Anesthesia, Local Clinical Trials

Peribulbar Block: Lidocaine-bupivacaine vs Lidocaine-bupivacaine-fentanyl

Start date: October 1, 2009
Phase: Phase 3
Study type: Interventional

Ophthalmological procedures such as cataract extraction can be carried out with a peribulbar block (PBB). The advantages of this anesthetic technique include a lower incidence of coughing, unwanted movements and emesis during awakening, in addition to providing adequate postoperative analgesia. The researchers want to investigate whether the use of fentanyl citrate by peribulbar route, when administered with a local anesthetic, shortens the anesthetic latency, interfere with the degree of akinesia and if provides greater postoperative analgesia.