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Analgesia clinical trials

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NCT ID: NCT04587505 Completed - Quality of Life Clinical Trials

Effect of Epidural Anesthesia and Analgesia on Quality of Recovery After Radical Prostatectomy.

QoR
Start date: April 1, 2019
Phase: Phase 4
Study type: Interventional

Postoperative quality of recovery (QoR) could be related to anesthesia and postoperative analgesia. This study is exploring early QoR after radical prostatectomy in the two groups of anesthesia. The first group had a light general anesthesia with lumbal epidural anesthesia and postoperative epidural analgesia with morphine and ropivacaine. The second group had general anesthesia and a continuous postoperative analgesia with tramadol. The postoperative QoR was evaluated 24 hours after surgery.

NCT ID: NCT04564729 Recruiting - Analgesia Clinical Trials

Shared Decision Aid for Post-Total Knee Arthroplasty Opioid Prescribing

Start date: November 2, 2020
Phase: N/A
Study type: Interventional

This will be a randomized controlled clinical trial in patients who have undergone primary unilateral total knee arthroplasty at Brigham and Women's Faulkner Hospital, Brigham and Women's Hospital and University of Chicago Medical Center. Study subjects will receive either a shared decision aid (SDA) about pain management or standard of care at the time of discharge. The impact of the SDA on the number of leftover opioid pills on postoperative day 30 and average NRS pain score on postoperative day 7 will be assessed.

NCT ID: NCT04554186 Recruiting - Analgesia Clinical Trials

Serratus Anterior Plane Block Versus Thoracic Paravertebral Block.

Start date: September 22, 2020
Phase: N/A
Study type: Interventional

Compare between serratus anterior plane block and thoracic Paravertebral block in analgesia for patients with multiple rib fractures

NCT ID: NCT04548323 Not yet recruiting - Analgesia Clinical Trials

Hypoalgesic Effects of Walking and Running Imagined

Start date: September 30, 2020
Phase:
Study type: Observational

The main objective is to identify the hypoalgesic effect of the imagination of actions in sedentary subjects with high levels of physical activity.

NCT ID: NCT04546113 Recruiting - Analgesia Clinical Trials

Erector Spinae Plane Block Versus Paravertebral Block for Analgesia After Cardiac Surgery (PEPS)

PEPS
Start date: January 7, 2021
Phase: N/A
Study type: Interventional

The purpose of this randomized double-blind study is to compare the analgesic efficacy of the bilateral Erector Spinae Plane (ESP) block versus the bilateral Thoracic Paravertebral block (TPVB), by ultrasound-guided single injection in patients who underwent sternotomy for cardiac surgery.

NCT ID: NCT04538235 Completed - Lung Cancer Clinical Trials

Analgesic Non Inferiority of the Thoracic Bi-block in Comparison With Thoracic Epidural for VATS.

ANESSTEVATS
Start date: October 20, 2019
Phase:
Study type: Observational

Video-Assisted thoracic surgery (VATS) is the standard treatment for localized lung cancer. However, there is no consensus on analgesic management in patients undergoing VATS. The aim of the study is to compare the analgesic efficacy of thoracic epidural with that a "Bi-block" combining an Erector Spinae muscle plane Block (ESP) and a Serratus Anterior Block (SAP) in patients undergoing VATS for lung or pleural surgery. Our main hypothesis is that the analgesic efficacy of the Bi-block, assessed by morphine consumption, is not inferior to that provided by a thoracic epidural during the first 48 hours after VATS. We conducted a age, gender and type of surgery-matched retrospective cohort study in the Department of Thoracic Anesthesia of the Montpellier University Hospital (France).

NCT ID: NCT04538105 Withdrawn - Analgesia Clinical Trials

Preoperative Fluoroscopy Guided Hip Articular Branch Blocks and Analgesic Outcomes Following Hip Arthroscopy

Start date: May 1, 2021
Phase: N/A
Study type: Interventional

Arthroscopic hip surgeries are increasingly being performed as both diagnostic and therapeutic interventions. These procedures are considerably painful, thus requiring the proper pain management techniques in order to provide patient satisfaction and sufficient pain control. Articular branch blocks have not been evaluated for their use in hip arthroscopy, but have potential advantages of blocking the sensory innervation of the entire hip joint, with minimal impact on motor innervation compared to alternative blocks. This current study aims to evaluate the efficacy of using preoperative fluoroscopic-guided blockade of articular branches of the femoral and obturator nerves for analgesic management of patients undergoing arthroscopy compared to a saline sham block. The utility of pre-operative hip articular branch block (ABB) prior to hip arthroscopy will provide superior pain management postoperatively compared to a saline sham block. We hypothesize that the ABB (Articular Branch Block) will reduce the area under the NRS pain scores by time curve (AUC) and decreased oral opioid milligram equivalent use in the first 24 hours post-operatively.

NCT ID: NCT04535089 Completed - Analgesia Clinical Trials

Opioid Sparing Analgesia: Dexmedetomidine Versus Lidocaine for Intracranial Surgeries in Children

Start date: October 1, 2020
Phase: Phase 1/Phase 2
Study type: Interventional

Perioperative pain control is necessary in children as inadequate treatment may lead to progression of perception of pain and development of chronic pain in the future. Anesthetists tend to adopt approach to perioperative control of pain by non-opioid drugs that mediate pain modulation. Its use as opioid sparing analgesia in different surgeries leading to mixed results.

NCT ID: NCT04531215 Recruiting - Analgesia Clinical Trials

Ultrasound Guided Retrolaminar Versus Erector Spinae Plane Block for Postoperative Analgesia

Start date: February 1, 2021
Phase: N/A
Study type: Interventional

Thoracic epidural anesthesia (TEA) and paravertebral block (PVB) have been utilized to give perioperative regional anesthesia in the trunk. TEA is technically troublesome in some cases, and is associated with a danger of serious complications, such as epidural hematoma, nerve injury, and hypotension. PVB has the benefit of perception of the needle position using ultrasonography. However, PVB is also additionally connected with a danger of serious complications, such as pneumothorax, hypotension, or nerve injury. Newer approaches to deal with PVB have been the focal point of numerous techniques lately; these methodologies incorporate retrolaminar block (RLB) and erector spinae plane block (ESPB)

NCT ID: NCT04528563 Completed - Analgesia Clinical Trials

Ketorolac for Moderate to Severe Abdominal Pain in Children

KETO-APP
Start date: May 5, 2021
Phase: Phase 3
Study type: Interventional

In children and adolescents (older than 6 years in age) who arrive in the pediatric emergency department because they have been having 5 days or less of abdominal pain (possible appendicitis), will patients who are treated with ketorolac get just as much pain relief as those patients treated with morphine? To answer this research question, we will need a large number of patients in a study. To ensure we have enough patients, we must include many hospitals in different cities and provinces in the same study. Before doing this, though, we must first test a smaller version of the study in our center at McMaster Children's hosptial. The goal of doing this at McMaster first is to make sure or understand: 1. We can enroll enough people in our study over 1 year 2. We can make sure that all the information we collect from patients is complete and nothing is missing 3. Reasons behind why people don't want to participate in the study 4. How satisfied patients and their caregivers were with the study