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Clinical Trial Summary

The goal of this randomized controlled trial is to compare pain, mouth opening, and alveolar osteitis following surgical extraction of bilateral symmetrical impacted lower third molars using two types of wound closures. Collagen plugs will be applied in the sockets of the study side followed by suture, while the controlled side will be sutured without a collagen plug. The study will include 40 patients aged between 18- 40 years old, medically fit (ASA1), who have bilateral symmetrical impacted lower third molars and visit the oral surgery clinics of King Saud Medical City for extraction. The main question is" Does intra-alveolar collagen application after surgical extraction of impacted lower third molars reduce the incidence of alveolar osteitis?


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT05850650
Study type Interventional
Source Riyadh Colleges of Dentistry and Pharmacy
Contact Nedal A Abu-Mostafa, Assistant P
Phone 00966506275782
Email nabumostafa@gmail.com
Status Not yet recruiting
Phase Phase 2
Start date May 1, 2023
Completion date November 15, 2023

See also
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Active, not recruiting NCT06435832 - Evaluations of the Effects of Tranexamic Acid and Chlorhexidine Gel on Alveolar Osteitis Incidence N/A
Recruiting NCT04853589 - Effect of Hyaluronic Acid on the Therapy of Alveolar Osteitis N/A
Completed NCT02382809 - Efficacy of 0.2 % Digluconate Chlorhexidine Mouthwash for Preventing Alveolar Osteitis After Third Molar Extraction Phase 4
Completed NCT00118820 - Antibiotic Efficacy in Third Molar Surgery Phase 3
Completed NCT04151147 - Effect of CGF on Frequency of Alveolar Osteitis Following Partially Erupted Mandibular Third Molar Surgery N/A
Enrolling by invitation NCT04476121 - Use of PRF in Treatment of Dry Socket. N/A
Completed NCT04507009 - Clinical Investigation of the Efficacy of CGF and Ozone in the Treatment of Alveolar Osteitis N/A