Use of PRF in Treatment of Dry Socket.

Alveolar Osteitis Clinical Trial

Official title:

Evaluation of Platelet Rich Fibrin Use in the Treatment of Dry Socket.

Clinical Trial Details — Status: Enrolling by invitation

Administrative data

• NCT number: NCT04476121
• Other study ID #: 0002
• Status: Enrolling by invitation
• Phase: N/A
• Start date: January 1, 2019
• Est. completion date: July 1, 2021

Study information

• Verified date: June 2020
• Source: Medical Universtity of Lodz
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

The aim of the study is to evaluate the influence of PRF application in case of alveolar osteitis.

Description:

The main objective was to compare the effects of using two different methods in the treatment of dry socket (alveolar osteitis), which is a postoperative complication of dental extraction. The first was Nipas, applied, if dry socket was diagnosed following a tooth extraction. In case of subsequent extraction of homonymous tooth and reoccurrence of dry socket, patients were treated with application of PRF.

Recruitment information / eligibility

• Status: Enrolling by invitation
• Enrollment: 30
• Est. completion date: July 1, 2021
• Est. primary completion date: July 1, 2021
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 18 Years to 70 Years

Eligibility

Inclusion Criteria:

• no known medical history of abnormal platelet counts,

• patients with symmetric teeth qualified for extraction,

Exclusion Criteria:

• patients treated previously for existing dry socket,

• patients allergic to acetylsalicylic acid ,

• systemic diseases,

• pregnancy,

• lactation,

• drugs known to affect the number or function of platelets,

• abnormal platelet counts,

Related Conditions & MeSH terms

• Alveolar Osteitis
• Dry Socket
• Osteitis

Intervention

Procedure:
• PRF application
PRF application into post-operative wound.

Drug:
• Nipas application
Nipas application into post-operative wound.

Locations

Country	Name	City	State
Poland	Department of Oral Surgery	Lodz

Sponsors (1)

Lead Sponsor	Collaborator
Medical Universtity of Lodz

Country where clinical trial is conducted

Poland, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Intensity of pain vs. PRF and Nipas application	In order to evaluate the relationship between intensity of pain after application of PRF and Nipas, Numeric Rating Scale pain scale is used. NRS is a horizontal line with an eleven point numeric range. It is labeled from zero to ten, with zero being an example of someone with no pain and ten being the worst pain possible.; The higher score means worse outcome in case of present study.	24 hours
Primary	Influence of treatment on bacteria levels in wounds	The second part of the study was dedicated to analyzing the number of bacteria in tooth extraction wounds.	24 hours