Non-exercise Physical Activity Intervention

Aging Clinical Trial

— STAND  

Official title:

Effects of Dynamic Standing vs. Static Standing on Subjective Fatigue Symptoms

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT04410055
• Other study ID #: STAND
• Status: Recruiting
• Phase: N/A
• Start date: January 8, 2012
• Est. completion date: January 8, 2022

Study information

• Verified date: May 2020
• Source: Science and Research Centre Koper
• Contact: Nicolaas Bohnen, MD, PhD
• Email: nbohnen[@]med.umich.edu
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

Physical inactivity is prevalent in older adults and poses a risk factor for the development of type 2 diabetes. The aim of this pilot study was to examine the effect of non-exercise physical activity using a standing desk on clinical variables in older adults with type 2 diabetes.

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 120
• Est. completion date: January 8, 2022
• Est. primary completion date: January 8, 2022
• Accepts healthy volunteers: No
• Gender: All
• Age group: 65 Years to 80 Years

Eligibility

Inclusion Criteria:

• older participants (65+ years) with clinically confirmed type 2 diabetes

• Body mass index above 25 and less than 40 kg/m2

Exclusion Criteria:

• participants unable to perform a short clinical and motor function test battery (sABC test, Mini-BEST)

Related Conditions & MeSH terms

• Aging
• Cognitive Change
• Diabete Mellitus
• Diabetes Mellitus

Intervention

Behavioral:
• Sitting
We proposed a dynamic standing approach (working while standing accompanied by small periodic stepping movements) as a more tolerable and thereby more applicative lifestyle modification. To evaluate this form on healthy subjects, three different conditions were applied: 3 hours of sitting, static standing and dynamic standing. Both standing conditions were done with height-adjustable table which was developed at the University of Michigan (Ann Arbor, Michigan, USA)
• Static standing
We proposed a dynamic standing approach (working while standing accompanied by small periodic stepping movements) as a more tolerable and thereby more applicative lifestyle modification. To evaluate this form on healthy subjects, three different conditions were applied: 3 hours of sitting, static standing and dynamic standing. Both standing conditions were done with height-adjustable table which was developed at the University of Michigan (Ann Arbor, Michigan, USA)
• Dynamic standing
We proposed a dynamic standing approach (working while standing accompanied by small periodic stepping movements) as a more tolerable and thereby more applicative lifestyle modification. To evaluate this form on healthy subjects, three different conditions were applied: 3 hours of sitting, static standing and dynamic standing. Both standing conditions were done with height-adjustable table which was developed at the University of Michigan (Ann Arbor, Michigan, USA)

Locations

Country	Name	City	State
United States	University of Michigan	Ann Arbor	Michigan

Sponsors (2)

Lead Sponsor	Collaborator
Science and Research Centre Koper	University of Michigan

Country where clinical trial is conducted

United States, 

References & Publications (3)

Dempsey PC, Larsen RN, Sethi P, Sacre JW, Straznicky NE, Cohen ND, Cerin E, Lambert GW, Owen N, Kingwell BA, Dunstan DW. Benefits for Type 2 Diabetes of Interrupting Prolonged Sitting With Brief Bouts of Light Walking or Simple Resistance Activities. Diabetes Care. 2016 Jun;39(6):964-72. doi: 10.2337/dc15-2336. Epub 2016 Apr 13. — View Citation

Sui W, Smith ST, Fagan MJ, Rollo S, Prapavessis H. The effects of sedentary behaviour interventions on work-related productivity and performance outcomes in real and simulated office work: A systematic review. Appl Ergon. 2019 Feb;75:27-73. doi: 10.1016/j.apergo.2018.09.002. Epub 2018 Sep 18. — View Citation

Wheeler MJ, Green DJ, Ellis KA, Cerin E, Heinonen I, Naylor LH, Larsen R, Wennberg P, Boraxbekk CJ, Lewis J, Eikelis N, Lautenschlager NT, Kingwell BA, Lambert G, Owen N, Dunstan DW. Distinct effects of acute exercise and breaks in sitting on working memory and executive function in older adults: a three-arm, randomised cross-over trial to evaluate the effects of exercise with and without breaks in sitting on cognition. Br J Sports Med. 2019 Apr 29. pii: bjsports-2018-100168. doi: 10.1136/bjsports-2018-100168. [Epub ahead of print] — View Citation

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Oxygen consumption	Oxygen uptake VO2 (ml/min/kg)	change in oxygen consumption between all three conditions, which will be measured with a minimum washout period of 3 days
Secondary	Executive control	Executive functions measured with Trail Making Test (seconds)	change in executive control and cognitive switching levels between all three conditions, which will be measured with a minimum washout period of 3 days
Secondary	Attention levels	Measuring attention with Stroop test (seconds)	change in attentional levels between all three conditions, which will be measured with a minimum washout period of 3 days