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Gene Expression Changes In Young and Geriatric Skin

Aging Clinical Trial

Official title:
Gene Expression Changes in Young and Geriatric Skin

Clinical Trial Summary

This study does not involve any particular diagnosis. The goal of this research study is to explore the effects of artificial sunlight (ultraviolet B radiation; UVB) on the skin of young adults versus geriatric adults. Sunlight exerts many effects on the body. There is evidence that in response to ultraviolet B radiation (UVB), which are the burning rays of sunlight, young adult skin responds differently than geriatric skin. In fact, researchers feel that this difference in how the skin reacts to UVB is why skin cancers are found in older skin. Researchers believe that a major difference between young adult and geriatric skin is that young skin has a lot of a protein called insulin-like growth factor-1 (IGF-1), whereas geriatric skin has very little. The current study will test how young adult versus geriatric skin responds to UVB, and if geriatric skin treated with an injection of small amount of IGF-1 drug will then act like young skin.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03932162
Study type Interventional
Source Wright State University
Contact Manager, Clinical Research Operations
Phone 937-245-7500
Email pturesearch@wrightstatephysicians.org
Status Recruiting
Phase Early Phase 1
Start date September 6, 2019
Completion date December 2025
View Details
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