Acute Respiratory Distress Syndrome Clinical Trial
Official title:
Effectiveness of Prone Positioning Combined With High-flow Nasal Cannula for Patients With COVID-19 Induced ARDS
Prone position (PP) has been proved to be effective in severe ARDS patients. On the other
hand, High flow nasal cannula (HFNC) may prevent intubation in hypoxemic Acute respiratory
failure (ARF) patients.
Our hypothesis is that the combination of PP and HFNC in patients with COVID19 induced ARDS
may decrease the need of mechanical ventilation.
Primary outcome: Therapeutic failure within 28 days of randomization (death or intubation).
Secondary outcomes: to analyze PP feasibility and safety in HFNC patients and to analyze
effectiveness in terms of oxygenation.
Methods: multicentric randomized study including patients with COVID19 induced ARDS supported
with HFNC. Experimental group will received HFNC and PP whereas observation group will
received standard care.
Optimization of non-invasive respiratory management of COVID19 induced ARDS patients may
decrease the need of invasive mechanical ventilation and subsequently ICU and hospital length
of stay.
n/a
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