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Acute Pain clinical trials

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NCT ID: NCT06267820 Completed - Clinical trials for Postoperative Pain, Acute

Postoperative Pain Control by Adding Ketorolac to Bupivacaine in Transversus Abdominis Plane Block in Children

Start date: June 1, 2023
Phase: Phase 2
Study type: Interventional

Control of of pain in children is fundamental. TAP block is associated with less side effects compared with other neuraxial techniques especially when done under ultrasound guidance. Ketorolac has analgesic effect comparable to morphine. Children were arranged randomly into two equal groups, forty-five children in each. Group (K) (n= 45): received ultrasound guided TAP block with bupivacaine 0.25% (0.5 ml/kg) and ketorolac (0.5 mg/kg). Group (T) (n =45): received ultrasound guided TAP block with bupivacaine 0.25% (0.5 ml/kg)

NCT ID: NCT06243419 Completed - Pain, Acute Clinical Trials

Veın Imagıng Devıce And Vırtual Realıty

ven-VR
Start date: May 1, 2022
Phase: N/A
Study type: Interventional

The aim of this study was to evaluate the effect of a vein imaging device and virtual reality distraction on the success of peripheral intravenous catheter (PIC) placement, intervention duration, emotional appearance, pain, fear, and anxiety related to PIC intervention in children aged 4-10 years in a pediatric emergency unit.

NCT ID: NCT06222047 Completed - Prematurity Clinical Trials

Pain and Comfort Level During Orogastric Catheter Insertion in Preterms

OGpreterm
Start date: March 1, 2022
Phase: N/A
Study type: Interventional

Purpose of the research: This research was planned to evaluate the effect of breast milk and dextrose application, which are pain relief methods, on the pain and comfort levels of preterm babies who will have an orogastric tube inserted in the 3rd and 4th levels of the Neonatal Intensive Care Unit. Hypotheses: H0: The methods used during orogastric tube insertion do not affect the pain and comfort levels of preterm babies. H1: Preterm babies who are breastfed feel less pain during orogastric tube insertion. H2: Preterm babies given dextrose during orogastric tube insertion feel less pain. H3: The comfort level of preterm babies who are breastfed during orogastric tube insertion is higher. H4: The comfort level of preterm babies given dextrose during orogastric tube insertion is higher. H5: There is a difference between the pain and comfort levels of preterm patients in terms of group, time, and group-time, depending on the intervention applied.

NCT ID: NCT06197620 Completed - Quality of Life Clinical Trials

Effectiveness of Thread Embedding Acupuncture Analgesia at the EX-B2 Point Combined With Standard Therapy After Laparoscopic Living Donor Nephrectomy

Start date: October 20, 2023
Phase: N/A
Study type: Interventional

Kidney transplantation is the main option besides hemodialysis and continuous ambulatory peritoneal dialysis (CAPD) to prolong and improve the quality of life for patients with end-stage renal disease. The main option for obtaining organs from living donors is surgical action to remove the kidney (nephrectomy) using the laparoscopic method (laparoscopic live donor nephrectomy or LLDN). Postoperative management of LDNH in the form of intravenous paracetamol 1000 mg cannot overcome innovative pain and has drug-related risk effects. Non-pharmacological pain management is the first line of pain management. One non-pharmacological therapy that can be an option is acupuncture. Thread embedding acupuncture (TEA) is an acupuncture method that uses certain medical threads such as catgut or polydioxanone (PDO) which are inserted into subcutaneous tissue or muscle at certain acupuncture points. The working mechanism of TEA in treating pain is through local mechanisms in the form of releasing adenosine which binds to adenosine A1 receptors, releasing substance P, inhibiting the expression and activation of Nuclear Factor Kappa B; through a segmental mechanism in the form of a control gate mechanism; through extrasegmental mechanisms in the form of downward pain inhibition pathways; through a central mechanism in the form of release of endogenous opioids in the hypothalamus. ATB can provide a continuous stimulating effect of infiltration and acceleration of tissue regeneration, increasing anti-pain.

NCT ID: NCT06192498 Completed - Anxiety Clinical Trials

Effects of Virtual Reality Glasses, Kaleidoscope and Distraction Cards on Pain and Anxiety During Blood Draw in Children

Start date: August 1, 2018
Phase: N/A
Study type: Interventional

The study was designed as a randomized controlled experimental research with the purpose of determining the effect of distraction by using Virtual Reality Glasses, Kaleidoscope and Distraction Cards in reducing pain and anxiety during blood draw in children.

NCT ID: NCT06191770 Completed - Pain, Acute Clinical Trials

Comparison of Morphine With Nalbuphine in a Multimodal Approach for Pain Relief in Patients Undergoing Gynecological Procedures: Randomized Controlled Double Blind Clinical Trial

Start date: October 1, 2019
Phase: N/A
Study type: Interventional

This study was conducted in the Aga Khan University Hospital, Karachi. Pakistan is developing country and overall shortage of Morphine in developing country. Rationalizing, in multimodal analgesia, Nalbuphine is equivalent to morphine in open Abdominal hysterectomy

NCT ID: NCT06131606 Completed - Pain, Acute Clinical Trials

Effect of Stress Ball in Angiography

Start date: January 10, 2023
Phase: N/A
Study type: Interventional

The target of this study was to determine the influence of stress ball application on pain and anxiety levels experienced by patients during angiography procedures.

NCT ID: NCT06131593 Completed - Pain, Acute Clinical Trials

TAP Block With Methyl-prednisolone as a Pain Treatment Modality After Total Abdominal Hysterectomy Procedures

Start date: December 1, 2023
Phase: N/A
Study type: Interventional

The aim of this work to compare between the efficacy of ultrasound guided TAP block with dexamethasone as an adjuvant versus ultrasound guided TAPB with methyl prednisolone as an adjuvant to local anesthetic for postoperative pain management in lower abdominal hysterectomy procedures.

NCT ID: NCT06130384 Completed - Pain Clinical Trials

Pain Reduction With Topical Bromfenac Versus Artificial Tear After Intravitreal Injection.

Start date: March 1, 2021
Phase: Phase 4
Study type: Interventional

The purpose of this prospective interventional study is to compare post-intravitreal injection pain between eyes receiving topical bromfenac versus artificial tears as an analgesic after intravitreal injection.

NCT ID: NCT06125613 Completed - Pain, Acute Clinical Trials

Influence of Kinesiophobia on the Excitability of Connections Parieto-frontal During a Pointing Movement in Humans

pIPS/M1
Start date: December 10, 2021
Phase: N/A
Study type: Interventional

Objective(s) of the trial: Better understand the interaction between kinesiophobia and motor control. Main objective: To measure the influence of induced kinesiophobia on functional connectivity between the posterior parieto-occipital region and the primary motor cortex in healthy subjects during a pointing task. Secondary objectives: The secondary objectives will be 1) to verify the excitatory influence of pIPS stimulation on the excitability of M1 at rest and 2) to establish whether there is a correlation between functional connectivity and the level of kinesiophobia ( as measured by the Tampa Scale)