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Dociparstat for the Treatment of Severe COVID-19 in Adults at High Risk of Respiratory Failure

Acute Lung Injury Clinical Trial

Official title:
A Phase 2/3 Study to Evaluate the Safety and Efficacy of Dociparstat Sodium for the Treatment of Severe COVID-19 in Adults at High Risk of Respiratory Failure

Clinical Trial Summary

This was a randomized, double-blind, placebo-controlled Phase 2/3 study to evaluate the safety and efficacy of dociparstat sodium in adult patients with acute lung injury (ALI) due to Coronavirus Disease 2019 (COVID-19). This study was designed to determine if dociparstat sodium could accelerate recovery and prevent progression to mechanical ventilation in patients severely affected by COVID-19.

Clinical Trial Description

This was a randomized, double-blind, placebo-controlled, Phase 2/3 trial to evaluate the safety and efficacy of dociparsat sodium in adults patients with severe COVID-19 who were at high risk of respiratory failure. Eligible subjects were with confirmed COVID-19 and required hospitalization and supplemental oxygen therapy. This study was designed to determine if dociparstat sodium could accelerate recovery and prevent progression to mechanical ventilation in patients severely affected by COVID-19. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04389840
Study type Interventional
Source Chimerix
Contact
Status Terminated
Phase Phase 2/Phase 3
Start date July 8, 2020
Completion date May 20, 2021
View Details
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