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Ischemic Post-conditioning in Acute Ischemic Stroke Thrombectomy (PROTECT-1b) — PROTECT  

Acute Ischemic Stroke Clinical Trial

Official title:
Effect of Ischemic Post-conditioning on Infarct Volume in Patients With Acute Ischemic Stroke After Mechanical Thrombectomy

Clinical Trial Summary

Ischemic post-conditioning is a neuroprotective strategy attenuating reperfusion injury in animal stroke models. The investigators have conducted a 3 + 3 dose-escalation trial to demonstrate the safety and tolerability of ischemic post-conditioning incrementally for a longer duration of up to 5 min × 4 cycles in stroke patients undergoing mechanical thrombectomy. This study aims to assess the infarct volume after ischemic post-conditioning in patients with acute ischemic stroke who are treated with mechanical thrombectomy.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05909982
Study type Interventional
Source Capital Medical University
Contact Xunming Ji, MD
Phone +86-10-83198952
Email jixm@ccmu.edu.cn
Status Recruiting
Phase Phase 1/Phase 2
Start date April 1, 2023
Completion date March 31, 2024
View Details
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