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Clinical Trial Summary

This study intends to further reveal the effect of RIC in stroke-related insomnia and explore its potential mechanisms.


Clinical Trial Description

Sleep disturbance after stroke is an important factor affecting the prognosis of stroke function. At present, most studies have focused on the diagnosis and treatment of sleep disordered breathing after stroke, while stroke-related insomnia has been neglected. Therefore, it is of great significance to explore a treatment that combines stroke protection with sleep improvement. Remote ischemic conditioning (RIC) triggers endogenous protective effect through transient and repeated ischemia in the limb to protect remote tissues and organs. The mechanisms of LRIC involve the regulation of autonomic nervous system, release of humoral factors, improvement of vascular endothelial function and modulation of immune/inflammatory responses, which participate in the regulation of sleep after stroke.Therefore, this study intends to conduct a randomized controlled trial to further reveal the effect of RIC in stroke-related insomnia and explore its potential mechanisms. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT05289518
Study type Interventional
Source Capital Medical University
Contact Xunming Ji, MD, PhD
Phone 101-83199430
Email jixm@ccmu.edu.cn
Status Not yet recruiting
Phase N/A
Start date April 1, 2022
Completion date December 13, 2023

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