Kanagawa Intravenous and Endvascular Treatment Registry — K-NET  

Acute Ischemic Stroke Clinical Trial

Official title: Kanagawa Intravenous and Endovascular Treatment Registry for Acute Ischemic Stroke

Status Enrolling by invitation

Clinical Trial Summary

The K-NET registry is a prospective, multicenter, observational registry study for all consecutive patients who received intravenous tPA therapy and/or endovascular treatment for acute ischemic stroke. This study is attended by 40 of the 58 Primary Stroke Centers in Kanagawa Prefecture, which is located in the Tokyo metropolitan area and has a population of 9.24 million. Patient enrollment for this study began in January 2018.

Clinical Trial Description

Inclusion criteria for this study are all consecutive patients who meet either or both of the patients who received intravenous tPA therapy for acute ischemic stroke and intention to perform EVT for large vessel occlusion. There were no exclusion criteria. The local neurologists, neurosurgeons, and neurointerventionalists at each institution made the decision to perform EVT and intravenous tPA.

The primary outcome was good as defined by the modified Rankin Scale (mRS) of 0 to 2 at three months. We also determined a favorable outcome: mRS 0-2 or not worsening of the mRS score at three months. Secondary analyses included predicting a favorable outcome using multivariate logistic regression analysis. ;

Related Conditions & MeSH terms

• Acute Ischemic Stroke
• Ischemic Stroke
• Stroke

• NCT number: NCT05213533
• Study type: Observational [Patient Registry]
• Source: St. Marianna University Toyoko Hospital
• Status: Enrolling by invitation
• Start date: January 1, 2018
• Completion date: October 2022