Acute Hypercapnic Respiratory Failure Clinical Trial
Noninvasive ventilation (NIV) is now a major therapeutic option to manage patients with
acute hypercapnic respiratory failure (AHRF). Otherwise, patient-ventilator interfaces are
determinant to get an optimal NIV efficacy in parallel with ventilatory comfort.
Facial masks during NIV are associated with deleterious consequences like gas leaks around
the mask, skin breakdown (especially on the nasal bridge), claustrophobia and mask
discomfort. In order to limit these side effects, a cephalic interface has been recently
designed. Cephalic mask covers the whole anterior surface of the face and excessive mask fit
pressure is therefore spread over a larger surface outside the nose area. However, this mask
has a high volume that may interfere with NIV efficacy and may also induce claustrophobic
sensations.
The aim of this study is to compare the clinical efficacy and tolerance of a cephalic mask
versus a conventional oronasal mask during AHRF.
n/a
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment
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