Acute Coronary Syndrome Clinical Trial
Official title:
Primary Prevention With Statin and Incidence of Recurrent Myocardial Infarction and Cardiogenic Shock in Post-Acute Coronary Syndrome Patients
This study aims to evaluate the effect of statin for primary prevention, towards lowering the incidence of recurrent myocardial infarction, cardiogenic shock and mortality in ACS patients.
Adult patients (≥ 18 years of age) with acute coronary syndrome which are diagnosed under
ICD-10 coding of I24.9 were included in this study. The inclusion criteria are patients with
primary diagnosis of I24.9 and with a complete record of prior medical and treatment history,
electrocardiographic findings, cardiac marker results and outcomes. Participants were grouped
into 2 groups - statin and non-statin based on prior history of statin use prior to ACS.
Diagnosis of ACS was made based on clinical, electrocardiographic and cardiac marker findings
found in the medical record.
Data such as age, sex, ethnic, education, prior medical and treatment history,
electrocardiographic and cardiac enzyme results as well as outcomes were collected from the
patients' medical records. Outcomes of interest were defined as either recurrent myocardial
infarction, cardiogenic shock, mortality or combinations of them as diagnosed in the medical
records. GRACE and TIMI Scores are calculated to predict in hospital and future mortality
rates.
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