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Acute Autoimmune Inflammatory Optic Neuritis clinical trials

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NCT ID: NCT03862313 Terminated - Clinical trials for Acute Autoimmune Inflammatory Optic Neuritis

Repetitive Transorbital Alternating Current Stimulation in Acute Autoimmune Optic Neuritis

ACSON
Start date: October 14, 2019
Phase: N/A
Study type: Interventional

Optic neuritis (ON) is an acute inflammatory, demyelinating attack of the optic nerve that triggers neurodegeneration in the entire visual pathway; translating into visual dysfunction. Currently, no neuroprotective therapy with satisfying evidence can be offered to patients. Repetitive transorbital alternating current stimulation (rtACS) is a methodology applied to electrically stimulate the retina and the optic nerve and is considered having neuroprotective- and restorative potential. The goal of this pilot study is to assess safety, tolerability and preliminary efficacy of rtACS as a treatment to improve visual functional as well as structural retinal outcomes in patients with a first-ever episode of autoimmune acute ON.