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Activated PI3Kdelta Syndrome (APDS); PASLI Disease clinical trials

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NCT ID: NCT02859727 Recruiting - Clinical trials for Activated PI3Kdelta Syndrome (APDS); PASLI Disease

Extension to the Study of Efficacy of CDZ173 in Patients With APDS/PASLI

Start date: September 8, 2016
Phase: Phase 2/Phase 3
Study type: Interventional

This study is designed to provide long-term CDZ173 treatment, a selective PI3Kδ inhibitor, to the patients with genetically activated PI3Kδ, i.e., patients with APDS/PASLI who participated in the CCDZ173X2201 study or who were treated previously with PI3Kδ inhibitors other than CDZ173. The study is open-label designed to establish the long-term safety, tolerability, efficay and pharmacokinetics of CDZ173 in the target population.