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Acquired Platelet Function Disorder clinical trials

View clinical trials related to Acquired Platelet Function Disorder.

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NCT ID: NCT02652897 Recruiting - Surgery Clinical Trials

Hemostasis Alterations in Neurosurgical Patients

Start date: May 2016
Study type: Observational

Prospective, observational study aimed to investigate the specific hemostatic alterations in patients undergoing glial tumor resection.

NCT ID: NCT01648712 Terminated - Clinical trials for Acquired Platelet Function Disorder

Platelet Function With New Pediatric Oxygenator and Heparin and Non Heparin Coating in Pediatric Cardiac Surgery

Start date: March 2013
Phase: N/A
Study type: Interventional

Optimal anticoagulation is mandatory during CPB in order to avoid hemostatic system activation. Platelet dysfunction is commonly observed after procedures performed under cardiopulmonary bypass (CPB). This is associated with a major risk of thrombosis and bleeding in the postoperative period. Coating of the surface has been shown to diminish these effects.Biocompatible surfaces, extracorporeal circulation technologies mimic critical characteristics of the vascular endothelium to provide thromboresistance and enhanced blood compatibility. Recently, a new physiologic non heparin coating with different functional aspects was developed as an alternative to heparin based biological coatings. This bio-passive Hydrophilic Polymer Coating Without Heparin (BalanceTM Bio-Passive surface) and pediatric oxygenation system (Affinity PixieTM Oxygenation System), is designed to mimic the natural interfaces of blood. The aim of this study is to compare the influence of a Balance - coated CPB system in pediatric use versus the Carmeda TM heparin-coated system in platelet function preservation and hemostatic activation.

NCT ID: NCT01354847 Completed - Clinical trials for Acquired Platelet Function Disorder

Influence of Extracorporeal Circulation on Platelet Function of Patients Undergoing Cardiac Surgery

Start date: June 2011
Phase: N/A
Study type: Observational

This study is planned to investigate the relationship between duration of extracorporeal circulation and the extent of (acquired) platelet dysfunctions in patients undergoing cardiac surgery.