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Absolute Uterine Factor Infertility clinical trials

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NCT ID: NCT03581019 Enrolling by invitation - Transplantation Clinical Trials

Uterus Transplantation From Deceased Donor - Gothenburg III

Start date: June 17, 2018
Phase: N/A
Study type: Interventional

Deceased donor uterus transplantation will be offered to patients that have either been excluded from Gothenburg II because of donor criteria or because of early graft failure in Gothenburg I and II

NCT ID: NCT03277430 Recruiting - Infertility, Female Clinical Trials

Uterus Transplantation From Live Donors and From Deceased Donors - Clinical Study

Start date: October 9, 2015
Phase: Phase 3
Study type: Interventional

Uterus transplantation (UTx) is the only causative treatment for congenital or acquired uterus absence. Individual cases of UTx from a live donor (LD UTx) with healthy child birth performed so far showed favourable outcomes. The present study will include both LD UTx and UTx from deceased donors after brain death (DBD UTx). The aim is treatment of uterine infertility by UTx. It is is an ethically justifiable life-promoting transplantation. Twenty UTx will be performed in 2 parallel arms: 10 LD UTx and 10 DBD UTx. Immunosuppression will be administered. Phases of the UTx procedure are: in vitro fertilization - cryopreservation of embryos - uterus retrieval - UTx - follow up - embryo transfer - pregnancy - child birth - later graft hysterectomy - life long follow up. Introduction of UTx into clinical practice may enable women with uterine infertility to have their own children.

NCT ID: NCT03138226 Recruiting - Cervical Cancer Clinical Trials

Living Donor Uterus Transplantation Between Identical Twins

Start date: January 1, 2017
Phase: N/A
Study type: Observational [Patient Registry]

Living donor uterus transplantation between identical twins, with IVF before and ET several months after transplantation. The donor should have completed childbirth.