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Abnormal Uterine Bleeding, Unspecified clinical trials

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NCT ID: NCT02059954 Completed - Uterine Fibroids Clinical Trials

Vaginal vs. Laparoscopic Hysterectomy

Start date: January 2014
Phase: N/A
Study type: Interventional

Hysterectomy for benign indication is one of the most common surgical procedures in women. Numerous reviews and guidelines recommend the vaginal approach for benign hysterectomy, but the proportion of laparoscopic (and robotic) hysterectomies is increasing. This study will compare a range of clinical and subjective outcomes of vaginal vs. total laparoscopic hysterectomy. Outcomes include operating time, postoperative recovery, return to work as well as cosmesis, quality of life and sexual health.

NCT ID: NCT01963403 Terminated - Clinical trials for Abnormal Uterine Bleeding, Unspecified

Treatment of Unacceptable Bleeding Patterns in ETG Implant Users With an Oral Contraceptive

Start date: December 2013
Phase: Phase 4
Study type: Interventional

This double-blinded, placebo-controlled, randomized trial will compare the effects of the use of a combined oral contraceptive pill to a placebo pill for women who are experiencing irregular and/or heavy bleeding associated with the use of an etonogestrel (ETG) implant. The hypothesis of the study is: - Use of combined oral contraceptive will significantly improve bleeding patterns for users of ETG implant - Continuation rate of ETG implant users will be increased by use of combined oral contraceptive in women desiring ETG implant removal because of the undesirable bleeding - Adverse events will be uncommon and acceptable to women who use a combined oral contraceptive with the ETG implant

NCT ID: NCT01929148 Recruiting - Clinical trials for Abnormal Uterine Bleeding, Unspecified

Prophylactic Bilateral Salpingectomy and Laparoscopic Myomectomy

Start date: August 2013
Phase: N/A
Study type: Interventional

We already demonstrated that the addiction of PBS to Total Laparoscopic Hysterectomy (TLH) has no negative effects in term of ovarian function, evaluated by anti-Müllerian hormone (AMH), Follicle Stimulating Hormone (FSH), Antral Follicle Count (AFC), mean ovarian diameters and Peak Systolic Velocity (PSV). In addition, in our experience, no negative surgical outcomes (in terms of operative time, intraoperative blood loss, postoperative hospital stay, postoperative return to normal activity and complication rate) are related to PBS step in TLH. Although the good statistical reliability of our retrospective data, we want to prospectively confirm our results. Moreover we aim to refine PBS safety demonstration by collecting also 3D ultrasound parameters [AFC, ovarian volume (OV), Vascularization Index (VI), Flow Index (FI) and Vascularization Flow Index (VFI)]. Hormonal and ultrasonographic parameters may possibly be unified into a new diagnostic algorithm (already at an advanced stage of production in UMG Department) able to estimate the ovarian function both in term of reproductive ability that in term of distance from menopause.