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TIA clinical trials

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NCT ID: NCT05439356 Recruiting - Ischemic Stroke Clinical Trials

Colchicine in High-risk Patients With Acute Minor-to-moderate Ischemic Stroke or Transient Ischemic Attack (CHANCE-3)

Start date: August 11, 2022
Phase: Phase 3
Study type: Interventional

This study is a multicentre, randomized, double-blind, placebo-controlled, investigator-sponsored study that aims to investigate the efficacy of colchicine in preventing recurrent stroke in the patients with acute minor-to-moderate ischemic stroke or TIA and a hsCRP level of ≥2mg/L.

NCT ID: NCT05378490 Recruiting - Stroke, Acute Clinical Trials

The Akershus Study of Ischemic Stroke and Thrombolysis -1

ASIST-1
Start date: January 1, 2012
Phase:
Study type: Observational

This observational study comprises consecutively patients with cerebrovascular diseases admitted to the Stroke Unit at Akershus University Hospital in Norway. Akershus University Hospital is the largest emergency care hospital in Norway and has a catchment area covering a population of 550.000, which is approximately 10 % of the Norwegian population and reasonably representative according to data from Statistics Norway. The hospital is public and serving both as a primary hospital and a university hospital. Due to the Norwegian, national, all-covering health-insurance, all patients enter the hospital and are considered for further in-patient care on the same conditions. The hospital has a stroke unit classified as a comprehensive stroke center according to European Stroke Organisation standards. Acute stroke management follows national and international guidelines. Overall, the ASIST-1 study will investigate management, outcome and prognosis of stroke and stroke care pathways and later follow up in primary care using several approaches combining existing clinical data from a representative population with different Norwegian health registries. Parts of the study are retrospective with prospective follow-up by health registries and parts of the study are prospective.

NCT ID: NCT05144932 Recruiting - Stroke Clinical Trials

StrokeAlarm Trial 2

Start date: January 1, 2022
Phase: N/A
Study type: Interventional

This open, multicenter, prospective, singel-arm study will evaluate usability and feasibility of a wearable stroke indication system (Stroke Alarm) in patients with recent TIA, recent minor stroke without persistent arm motor deficit, or atrial fibrillation up to 1 month.

NCT ID: NCT05134454 Recruiting - Ischemic Stroke Clinical Trials

Atrial Fibrillation Screening Post Ischemic Cerebrovascular Events

AF-SPICE
Start date: January 20, 2022
Phase: N/A
Study type: Interventional

Stroke is one of the leading causes behind death and permanent disability in adults. Atrial fibrillation (AF) is the most common clinical arrhythmia and its prevalence is steeply increasing with age. Atrial fibrillation is associated with a manifold increase in the risk for stroke. It is considered important to investigate the heart rhythm in stroke survivors without previously known AF, because detection of AF will prompt a change in antithrombotic treatment with subsequent lowering of the risk of recurrent stroke. There are so far very few studies on the prognostic impact of ECG investigations post stroke. Despite this knowledge gap, ECG investigation post stroke is given high priority in national and international guidelines. Considerable clinical resources are currently invested in these ECG investigations without knowledge of its utility. The investigators plan a nationwide, randomised, register-based study (RRCT) including patients aged at least 70 years receiving in-hospital care for stroke or TIA (Transient Ischemic Attack). Included patients will be randomised to standard investigation (1-2 days of ECG ) or extended ECG investigation (14 days of ECG performed at least twice). Patients diagnosed AF will be offered anticoagulation treatment. Long-term follow-up will be performed via swedish health care registers. The result of this trial will have major impact on the ECG screening recommendations for patients who have had stroke, a large group of patients with dismal prognosis.

NCT ID: NCT04205006 Enrolling by invitation - Ischemic Stroke Clinical Trials

Stroke Card Long-term Follow-Up

Start date: December 16, 2019
Phase:
Study type: Observational

We undertook the STROKE-CARD trial (NCT02156778) between 2014 and 2018 with follow-up until 2019 to evaluate the efficacy of the Post-Stroke disease-management program STROKE-CARD care. To further investigate the long-term efficacy of STROKE-CARD care all participants of the original trial will be invited for a Long-term in Person follow-up (3 - 6 years).

NCT ID: NCT04011514 Active, not recruiting - Stroke Clinical Trials

Querying Stroke Unit Nursing Interventions in the Emergency Department

Start date: September 28, 2018
Phase:
Study type: Observational

The aim of the study is to monitor if specialized stroke nurses as team partners in the ED can reduce hospital acquired infections. The study is designed as pre- post-intervention study in which specialized SU nurses partner with ED nursing staff to asses and screen stroke admissions in the ED.

NCT ID: NCT03979781 Completed - Ischemic Stroke Clinical Trials

Personalized Antiplatelet Secondary Stroke PRevenTion

PASSPoRT
Start date: June 11, 2018
Phase: Phase 2
Study type: Interventional

This is a descriptive study designed to evaluate the safety and feasibility of a precision medicine approach to antiplatelet selection for secondary stroke prevention.

NCT ID: NCT03937934 Completed - Obesity Clinical Trials

Study Title: Food Rx

Start date: May 20, 2019
Phase: N/A
Study type: Interventional

Researchers are trying to determine if subjects with lack of access to healthy food and a long term health problem, are helped by a weekly box of healthy groceries and nutrition education.

NCT ID: NCT03891277 Recruiting - Iron-deficiency Clinical Trials

Efficacy and Safety of Ferrous Iron on the Prevention of Vascular Cognitive Impairment Among Patients With Cerebral Infarction/TIA (FAVORITE)

FAVORITE
Start date: April 1, 2019
Phase: Phase 2
Study type: Interventional

The prevalence of Vascular Cognitive Impairment(VCI) is high in patients after ischemic stroke or transient ischemic attack(TIA) . Effective therapy for the prevention of VCI remains limited. The primary purpose of this study is to evaluate the efficacy and safety of Ferrous iron versus placebo on the prevention of vascular cognitive impairment among patients with ischemic stroke/TIA complicated with Hemoglobin deficiency.

NCT ID: NCT03821181 Not yet recruiting - Stroke Clinical Trials

The Effect of RIC on TIA/Stroke in Children With Moyamoya Disease

RIC-PMD-1
Start date: December 8, 2019
Phase: N/A
Study type: Interventional

Moyamoya disease is a common reason of transient ischemic attack (TIA) and stroke in children. Remote ischemic conditioning (RIC) has been shown to prevent recurrent stroke in intracranial arterial stenosis, but it is unclear whether RIC can prevent TIA or stroke in children with moyamoya disease. This study aims to evaluate the effect of RIC on TIA/stroke in children with moyamoya disease.