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Syndrome clinical trials

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NCT ID: NCT01912209 Completed - Obesity Clinical Trials

A Web-based Approach to Treating Cardiovascular Disease Risk in Employees With Metabolic Syndrome

BEHHS
Start date: August 2013
Phase: N/A
Study type: Interventional

The purpose of BEHHS is first to assess the baseline sub-clinical disease in a population of Baptist Health Employees who have Metabolic Syndrome, a known contributor to cardiovascular disease. Second, the investigators wish to encourage a healthy lifestyle through personalized nutrition and fitness advice, delivered as part of a web based program, which will in turn lead to increases in heart healthy behaviors such as increased consumption of heart healthy foods, increased exercise initiation, and more positive attitudes about health. To assess this, the investigators plan to randomize 200 employees with Metabolic Syndrome to either the new web-based diet and lifestyle program, or to care-as-usual, which is the currently offered MyWellnessAdvantage and WebMD websites. The investigators hypothesize that the web-based group will show greater improvements in physical health (such as weight loss, cholesterol reduction, etc.) as well as increased consumption of heart healthy foods, exercise initiation, and quality of sleep as measured by surveys administered at the 4,8, and 12 month follow-up appointments.

NCT ID: NCT01911884 Completed - Clinical trials for Surgical or Vaginal Dilatation of Vaginal Aplasia

Assessment of Quality of Global and Sexual Life and Impact of Surgical and Non Surgical Vaginal Aplasia in Patients With a Rokitansky Syndrome

MRKH
Start date: October 11, 2012
Phase: N/A
Study type: Interventional

The principal objective is to assess the general health status and the sexual health status of women with Rokitansky syndrome having received a surgical or non surgical treatment. The secondary purpose is to assess the anatomical aspect and the quality of sexual life. To search a correlation between the anatomical result, the general and sexual quality of life. To compare the different techniques of medical follow-up in terms of anatomic results, general quality of life, sexual quality of life, complications and morbidities. To evaluate social inclusion of these women with their family situation, social and professional category and their job. At the same time, we propose an evaluation with a psychologist to study the impact of the announcement of the diagnosis. This impact study is conducted at a distance from diagnosis.

NCT ID: NCT01911455 Completed - Fragile X Syndrome Clinical Trials

Study of Acamprosate in Fragile x Syndrome

Start date: August 27, 2013
Phase: Phase 1
Study type: Interventional

In this research study we want to understand the effectiveness of a drug treatment, acamprosate, for interfering symptoms (i.e., inattention/hyperactivity, social impairment) associated with Fragile X Syndrome (FXS).

NCT ID: NCT01911299 Completed - Clinical trials for Fetal Alcohol Spectrum Disorders

Choline Supplementation in Children With Fetal Alcohol Spectrum Disorders

Start date: May 2013
Phase: Phase 2
Study type: Interventional

The purpose of this study is to determine whether choline supplementation can improve cognitive functioning of children with prenatal alcohol exposure.

NCT ID: NCT01911078 Completed - Metabolic Syndrome Clinical Trials

Renal Sympathetic Denervation in Metabolic Syndrome (Metabolic Syndrome Study)

Start date: September 2014
Phase: N/A
Study type: Interventional

The purpose of this clinical investigation is to determine the effects of renal sympathetic denervation on insulin resistance and muscle sympathetic nerve activity in patients with metabolic syndrome.

NCT ID: NCT01910766 Completed - Clinical trials for Polycystic Ovary Syndrome

Coenzyme Q10 and Clomiphene Citrate (CC) for Ovulation Induction in Polycystic Ovary Syndrome

Start date: January 2010
Phase: N/A
Study type: Interventional

Objective of the study was to evaluate the effect of combination of oral Coenzyme Q10 (CoQ10), with clomiphene citrate (CC) for ovulation induction in CC-resistant polycystic ovary syndrome (PCOS).In a prospective controlled randomized trial performed in a university hospital and private practice setting. One hundred ten infertile women with PCOS resistant to CC were randomized to either combined CC/CoQ10 (51 patients, 82 cycles) or CC 150 mg/day alone (50 patients, 71 cycles) for ovulation induction in patients with CC-resistant PCOS. Main outcome measures: Number of follicles, serum E2, serum P, endometrial thickness, pregnancy rate (PR) and miscarriage rate.

NCT ID: NCT01907555 Completed - Cohen Syndrome Clinical Trials

Clinical, Molecular and Physiopathological Study of Cohen Syndrome and Cohen-like Syndromes

Start date: July 24, 2013
Phase: N/A
Study type: Observational [Patient Registry]

This project will make it possible to better understand the natural history of Cohen Syndrom and the phenotypes associated with mutations in the VPS13B gene, to improve the therapeutic management of patients. It will also provide a better description of Cohen-like syndrome for genetic counselling for the families concerned.

NCT ID: NCT01906957 Terminated - Metabolic Syndrome Clinical Trials

Cognition and Exercise Training

COGNEX-2
Start date: September 2013
Phase: N/A
Study type: Interventional

The aim of study is to investigate the impact of two different training modalities (high intensity interval training (HIIT) versus moderate intensity continuous exercise training (MICET) on cognitive performance, cerebral oxygenation, cardiac output and physical fitness in older healthy adults, patients with metabolic syndrome, coronary heart disease and heart failure. The investigators hypothesized that HIIT modality will lead to a larger improvement in physical fitness (i.e. VO2peak), cardiovascular parameters (cardiac output and stroke volume) and cognitive performance at rest and during submaximal exercise. The primary endpoint will be the improvement in cognitive performance.

NCT ID: NCT01906749 Recruiting - Clinical trials for Acute Coronary Syndrome

Colchicine for Acute Coronary Syndromes

COACS
Start date: June 2013
Phase: Phase 4
Study type: Interventional

Multicenter, double blind, randomized trial to assess the effect of low-dose colchicine (0.5mg/day) on overall mortality, new coronary syndromes, and ischemic stroke at 2 years after an acute coronary syndrome. The study hypothesis is that colchicine may reduce the specified combined endpoint from 16% to 7-8% at a 2-years follow-up.

NCT ID: NCT01906307 Terminated - Clinical trials for Hepatorenal Syndrome Type I and Type II

A Phase 1 Study of LJPC-501 in Patients With Hepatorenal Syndrome

Start date: March 2014
Phase: Phase 1
Study type: Interventional

Hepatorenal syndrome (HRS) is a life-threatening condition marked by rapid decline in kidney function in patients with liver cirrhosis or fulminant liver failure. Vasodilation in the gastrointestinal region is largely thought to contribute to the disease. LJPC-501 is a vasoconstrictor that may restore proper circulation and kidney function in patients with HRS.