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Syndrome clinical trials

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NCT ID: NCT02974569 Completed - Cancer Clinical Trials

Improving Symptom Self-management in Adolescents & Young Adults With Cancer

CSCAT2
Start date: November 1, 2016
Phase: N/A
Study type: Observational

This study evaluates the use of the Computerized Symptom Capture Tool (C-SCAT), which creates an image of the symptoms the participant is experiencing, for improving symptom self-management in adolescents and young adults with cancer. In this one-group trial, participants will complete the C-SCAT and use it during two clinic visits with their oncology providers.

NCT ID: NCT02973542 Active, not recruiting - Clinical trials for Irritable Bowel Syndrome

Ethosuximide to Treat IBS

IBSET
Start date: April 30, 2018
Phase: Phase 2
Study type: Interventional

Abdominal pain remains the most deleterious symptom for patients with irritable bowel syndrome (IBS) and is causing a significant alteration of their quality of life. The visceral hypersensitivity seems to be one of the key mechanisms that could explain the abdominal pain in these patients. Current treatments, mainly symptomatic, are of limited effectiveness, especially in terms of relief of abdominal pain. The study will aim to evaluate the effectiveness of ethosuximide on abdominal pain in patients with IBS, its tolerance and its impact on patient quality of life, severity of symptoms related to IBS and the use of analgesics / antispasmodic / regulators transit.

NCT ID: NCT02972359 Completed - Clinical trials for Complex Regional Pain Syndrome

Safety of Intravenous Neridronic Acid in CRPS

Start date: December 20, 2016
Phase: Phase 3
Study type: Interventional

The aim of this trial was to investigate the safety of intravenous neridronic acid in patients with complex regional pain syndrome (CRPS). The trial was divided into 3 periods: a 60-day enrollment period, a treatment period consisting of 4 infusions over 10 days, and a follow-up period of approximately 50 weeks (with visits at Week 2, Week 6, Week 12, Week 26, Week 39, and Week 52).

NCT ID: NCT02971254 Completed - Down Syndrome Clinical Trials

The Effects of Inhalational Anaesthetics in Cognitive Functions in Down Syndrome Patients

Start date: December 1, 2016
Phase: Phase 2
Study type: Interventional

Recovery of the cognitive functions and recovery features after general anaesthesia in Down syndrome patients. A comparison of Sevoflurane and Desflurane.

NCT ID: NCT02971072 Completed - Pain Clinical Trials

Neurophysiology of Weakness and Exercise in Rotator Cuff Tendinopathy

Start date: July 2014
Phase: N/A
Study type: Interventional

The purpose of this study is to examine deficits in activation and motor patterns, as well as central drive in patients with rotator cuff tendinopathy. There are three specific aims: (1) determine the effect of acute pain relief on rotator cuff muscle activation in patients with rotator cuff tendinopathy, (2) determine the effect of exercise on rotator cuff muscle activation in patients with rotator cuff tendinopathy, and (3) compare rotator cuff muscle activation between patients with rotator cuff tendinopathy and healthy controls.

NCT ID: NCT02970591 Completed - Clinical trials for Irritable Bowel Syndrome

A Comparison of Three Different Treatment Options for Irritable Bowel Syndrome

CARIBS
Start date: January 2017
Phase: N/A
Study type: Interventional

Irritable Bowel Syndrome is a common disease to which there is no curable treatment. Diet is considered to trigger symptoms associated with the clinical picture of IBS, and dietary treatment is thus believed to relieve the symptoms of IBS. As the disease is very heterogeneous in its manifestation, different treatment options might be indicated depending on the predominant symptom. To investigate the response to different dietary treatment options, a randomized controlled intervention trial will be carried out in adult patients (>18 y) with IBS according to Rome IV criteria. The aim of this study is to compare the response to two different dietary treatments or optimized medical treatment.

NCT ID: NCT02970240 Completed - Clinical trials for Chronic Fatigue Syndrome

Cardiopulmonary Testing in ME/CFS to Improve Diagnostic Accuracy

Start date: June 2014
Phase:
Study type: Observational

Circumstantial evidence suggests that patients diagnosed with myalgic encephalopathy/chronic fatigue syndrome (ME/CFS) perform worse on day 2 in a 2-day consecutive cardiopulmonary exercise test (CPET). The aim of this study is to examine if CPET can distinguish between ME/CFS patients and healthy controls.

NCT ID: NCT02970162 Completed - Clinical trials for Lambert-Eaton Myasthenic Syndrome

Phase 3 Study to Evaluate Efficacy of Amifampridine Phosphate in Lambert-Eaton Myasthenic Syndrome (LEMS)

Start date: November 2016
Phase: Phase 3
Study type: Interventional

This study evaluates the effect of withdrawing amifampridine phosphate treatment from patients with LEMS. One half of the patients will continue to receive amifampridine phosphate and the other half will receive placebo, during this double-blind study.

NCT ID: NCT02969980 Completed - Clinical trials for Myelodysplastic Syndromes

Hematopoietic Cell Transplantation With Post-transplantation Cyclophosphamide in MDS

Start date: November 2016
Phase: Phase 2
Study type: Interventional

This study is conducted to evaluate the feasibility and efficacy of post-transplantation cyclophosphamide with myeloablative or reduced-intensity conditioning regimen for allogeneic hematopoietic cell transplantation (HCT) in patients with myelodysplastic syndrome (MDS).

NCT ID: NCT02969720 Completed - Clinical trials for Metabolic Syndrome x

Therapeutic Efficacy of Phytosterols on Metabolic Syndrome

FESIME
Start date: January 8, 2018
Phase: N/A
Study type: Interventional

The objective is to evaluate therapeutic efficacy of 2 grams nano-phytosterols daily supplemention on diagnosis criteria of metabolic syndrome.