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Syndrome clinical trials

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NCT ID: NCT03077009 Recruiting - Clinical trials for Non-Insertional Achilles Tendinopathy

Functional Improvement and UTC of the Achilles Tendon After Sodium Hyaluronate Injection for Plantaris Syndrome

Start date: March 20, 2017
Phase: Phase 4
Study type: Interventional

This is a study to assess the benefit of sodium hyaluronate (Ostenil) injection for plantaris friction syndrome (PFS) associated with midportion Achilles tendinopathy. Functional outcome scores will be recorded prior to treatment and at regular intervals up to 2 years. Changes in tendon structure will be assessed using ultrasonographic tissue characterisation (UTC). UTC will be performed prior to treatment and also at regular intervals up to 6 months following injection.

NCT ID: NCT03074227 Recruiting - Clinical trials for Irritable Bowel Syndrome

The FAIS-Trial: Faecal Microbiota Transplantation (FMT) in Adolescents With Refractory Irritable Bowel Syndrome (IBS)

FAIS
Start date: November 23, 2017
Phase: N/A
Study type: Interventional

A Double-blind randomised placebo-controlled pilot study as well as a reversed translational part To investigate whether two faecal transplantations from either allogeneic (healthy) or autologous (own) donor, administered through a nasoduodenal tube, has beneficial effects on irritable bowel syndrome (IBS) symptoms such as abdominal pain frequency and severity. Secondary objective is to study microbiota changes in faeces samples.

NCT ID: NCT03072849 Recruiting - Clinical trials for Bronchiolitis Obliterans Syndrome

Early Detection and Management of Bronchiolitis Obliterans Syndrome Following Pediatric Hematopoietic Stem Cell Transplantation

Start date: April 2015
Phase: N/A
Study type: Observational

This study aims to determine whether or not early spirometric detection and management of obstructive lung disease with combined fluticasone/azithromycin/montelukast therapy (FAM) can attenuate declining lung function, prevent the development of bronchiolitis obliterans, and improve patient outcomes following hematopoietic stem cell transplant.

NCT ID: NCT03072498 Recruiting - Clinical trials for Myelodysplastic Syndromes(MDS)

Collection of Samples From Patients With MDS

Start date: April 6, 2017
Phase:
Study type: Observational

The purpose of this study is to collect information and bone marrow, blood, saliva, cheek cells and skin to be used in the laboratory to assist the sponsor in identifying a new way of treating MDS.

NCT ID: NCT03060330 Recruiting - Clinical trials for Chronic Constipation

Laparoscopic Ventral Mesh Rectopexy Combined With or Without Stapled Trans-anal Rectal Resection for Obstructed Defecation Syndrome

Start date: April 26, 2017
Phase: N/A
Study type: Interventional

Obstructed defecation syndrome (ODS) is a common problem in women. Rectal prolapse and rectocoele are frequently identified in patients with ODS. Surgery is the only definite treatment for those patients and is preferably performed minimally invasive. The most used procedures are laparoscopic ventral mesh rectopexy (LVMR) and stapled trans-anal rectal resection (STARR). However, high-level prospective studies on treatment strategies for ODS currently are lacking and, thus, no consensus exist regarding the optimal treatment for patients with ODS. This study aimed to compare LVMR alone and LVMR combined with STARR evaluating functional and anatomical results.

NCT ID: NCT03060005 Recruiting - Clinical trials for Meibomian Gland Dysfunction

Is Sjögren's Syndrome Associated With Meibomian Gland Dysfunction ?

Start date: May 1, 2017
Phase: N/A
Study type: Interventional

The investigators hypothesize that the dry eye caused by SS may include the evaporative type, resulting from the MGD. Furthermore, the investigators hypothesize that both pSS and sSS are associated with MGD.To test our hypothesis, we conducted a prospective clinical study in patients with SS (both pSS and sSS) and MGD, and the normal population All subjects were matched for both age and gender and assessed for tear function and ocular surface signs and symptoms.

NCT ID: NCT03059420 Recruiting - Facial Palsy Clinical Trials

Genetic Studies of Strabismus, Congenital Cranial Dysinnervation Disorders (CCDDs), and Their Associated Anomalies

Start date: February 1, 2004
Phase:
Study type: Observational

The purpose of this study is to identify genes associated with impaired development and function of the cranial nerves and brainstem, which may result in misalignment of the eyes (strabismus) and related conditions.

NCT ID: NCT03059173 Recruiting - Clinical trials for Polycystic Ovary Syndrome

Interest of Myo-inositol Supplementation in Women With Polycystic Ovarian Syndrome

MYOPK
Start date: September 12, 2023
Phase: Phase 3
Study type: Interventional

The main objective will be to check if MyoInositol (MYO) reduces the total resistance rate to Clomiphene Citrate (CC). For this, our study will be controlled, randomized and double blinded. It will include patients with PCOS (polycystic ovary syndrome, defined by the Rotterdam criteria) who wish to become pregnant and are eligible to simple ovulation induction by CC. Half of them will receive MYO + levomefolic acid (5-MTHF) in addition to the CC, while the other half will receive a placebo containing only 5-MTHF in addition to the CC. The MYO supplementation will be initiated at least one month before taking CC and will be continued throughout this treatment until pregnancy or before switching to another type of treatment for ovulation induction if no pregnancy is obtained after 6 ovulatory cycles.

NCT ID: NCT03057691 Recruiting - Depression Clinical Trials

The Impact of Depression and/or Anxiety on PCI Patients

Start date: March 11, 2017
Phase:
Study type: Observational

The purpose of this study is to evaluate how depression and/or anxiety could effect the prognosis of the patients post-ACS after PCI.

NCT ID: NCT03056937 Recruiting - Obesity Clinical Trials

Effects of Bariatric Surgery on Inspiratory Metaboreflex in Obese Subjects

Start date: February 1, 2016
Phase: N/A
Study type: Observational

The hypothesis of this study is that reductions in body weight could improve inspiratory muscle function attenuating the inspiratory metaboreflex in metabolically healthy obese individuals and obese individuals with metabolic syndrome.