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Stress clinical trials

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NCT ID: NCT00857051 Completed - Stress Clinical Trials

Postpartum Support: Can we Facilitate the Transition to Motherhood?

Start date: March 2009
Phase: N/A
Study type: Interventional

We are conducting a study to look interventions that may reduce stress in the postpartum period for first- time mothers. One of these interventions is an educational film that describes the common stressors that first-time parents go through in the early postpartum period. The other is a hotline service that women can call at anytime during the first 3 months postpartum to ask about problems she or the baby may be experiencing.

NCT ID: NCT00824941 Terminated - Obesity Clinical Trials

Brain-Gut Interactions in Overweight and Normal Weight Patients With Chronic Abdominal Pain

Start date: February 6, 2009
Phase:
Study type: Observational

About 15 to 20 percent of individuals living in the United States have chronic abdominal pain, often of unknown origin, which is often difficult to diagnose and treat. One possible cause of chronic abdominal pain is an inflammation of the intestines, but it is not known whether the two are related. Furthermore, although overweight people tend to be more likely to have increased inflammation, it is not known whether there is a connection between increased body weight and chronic abdominal pain. This study will examine the relationship between symptoms of chronic abdominal pain and intestinal inflammation by comparing the medical test results of normal weight and overweight patients who have a history of chronic abdominal pain. This study will include 224 subjects, who must be men and women between the ages of 13 and 45. Half the subjects will be healthy participants, and half will have had chronic abdominal pain of unknown origin for longer than 6 months. Female participants must take a urine pregnancy test before starting the study, and will not be allowed to participate if the test is positive. During the study, patients will visit the NIH Clinical Center on two occasions for testing. On the first visit, patients will provide a medical history, including information about current medications or natural remedies and tobacco and alcohol use, and will also fill out questionnaires to provide information about symptoms, current levels of gastrointestinal pain, and general quality of life. The study researchers will conduct a physical examination, measure patients height and weight, and draw blood for testing. Patients will be asked to not eat or drink anything for 8 hours before the second visit, and will be asked to bring a bathing suit and a swim cap to the Clinical Center. On the day of the visit, patients will fill out questionnaires to provide information about symptoms, current levels of gastrointestinal pain, and general quality of life. Patients will also provide a blood sample for testing. Researchers will measure patients blood pressure and heart rate, height, weight, waist/hip circumference, and intra-abdominal measurement. Patients will also be asked to put on the bathing suit and swim cap to have their body fat measured using a machine called the BOD POD. To test the gastrointestinal system, patients will then be asked to drink a sugar-based test solution, and researchers will collect all voided urine for the next 5 to 6 hours. (Patients may drink water during this time.) On either Day 1 or Day 2 of the study, patients will sip, swish and spit an additional sweet taste solution. Patients will sip, swish, and spit different concentrations of this sweet taste solution, for a total of 25 tastings of this solution. Subjects will then complete questionnaires about their sweetness preferences related to these 25 tastings.

NCT ID: NCT00814931 Completed - Anxiety Clinical Trials

Examining the Effects of CXB722 in Neuroendocrine Stress Response in Healthy Males

CXB722-100
Start date: December 2008
Phase: Phase 1
Study type: Interventional

The purpose of this study is to assess the effects of CXB722 on neuroendocrine stress response and subjective reports related to mood and stress during and after experimentally induced stress among healthy young males.

NCT ID: NCT00807157 Completed - Anxiety Clinical Trials

Evaluation of a Probiotic On Anxiety and Stress in Healthy Adults Sensible to Daily Stress

BIOSTRESS
Start date: December 2008
Phase: N/A
Study type: Interventional

The purpose of the the study is to determine if PROBIOSTICK® decrease stress and anxiety of people sensible to daily stress.

NCT ID: NCT00789438 Completed - Pain Clinical Trials

Evaluation of the Surgical Pleth Index During Spinal and General Anesthesia

Start date: October 2008
Phase: N/A
Study type: Observational

The Surgical Pleth index (SPI) has been introduced as a non invasive tool to "measure" stress and pain during surgery. Preliminary studies were performed in patients under general anaesthesia with propofol and remifentanil. These trials showed a good correlation between SPI and aching procedures and a negative correlation between SPI and the remifentanil dosage. Hence, it was concluded that SPI may be a bedside tool to measure `pain` during surgery. So far, no study investigated SPI during regional anaesthesia.

NCT ID: NCT00789412 Completed - Pain Clinical Trials

Surgical Stress Index as a Tool for Monitoring Analgesia and/or Sedation in Critically Ill Patients

Start date: August 2008
Phase: N/A
Study type: Observational

The hypothesis of the study is: Does the Surgical Stress Index (SSI) correlate with the Behavioral Pain Scale (BPS), the Ramsay Sedation Scale (RSS)and/or the Behavioral Pain Scale(BPV) and can therefore be used to monitor the quality of analgosedation in noncommunicative intensive care unit patients?

NCT ID: NCT00787423 Completed - Stress Clinical Trials

Developing Field Tools for Real-Time Assessment of Exposure to Psychosocial Stress and Drug Use in an Outpatient Treatment Population

Start date: July 14, 2009
Phase:
Study type: Observational

Background: - Researchers are interested in developing more accurate methods to assess environmental influences on psychological stress and drug use. One key to a more accurate assessment of environmental influences is minimizing the delay between exposure and reporting. Portable devices such as personal digital assistants (PDAs) and global positioning system (GPS) units may be able to provide a more real-time image of these factors. Objectives: - To assess the use of PDAs to measure stress and drug use, and GPS units to assess the effects of neighborhood environment in an outpatient treatment population. Eligibility: - Individuals from 18 to 75 years of age who are current heroin users seeking treatment for addiction and who spend most of their time in Baltimore city. - Participants must be able to visit the research and treatment center at least three times per week for regular tests. Design: - Participants will be in the study for approximately 28 weeks (7 months). - A series of three laboratory session examining responsiveness to standardized stressors will occur both early in treatment and will be repeated late in treatment. - Participants will undergo 18 weeks of daily methadone maintenance. Urine samples will be collected three times weekly. - To track drug use, stress, and geographical location (a measure of environmental risk), each participant will carry a PDA and a GPS unit for 16 of the 18 weeks. Participants will make entries (1) each time that they use a drug and (2) each time they feel overwhelmed, anxious, or stressed more than usual. Participants will also make three random-signal-triggered recordings per day and one brief (end of day) recording. - Retrospective self-report questionnaires on drug use and stress will be given regularly. - After 18 weeks of methadone maintenance, participants will discontinue carrying the PDA and GPS unit and will have the choice of transferring to a community clinic or undergoing a 10-week taper from methadone at the research clinic. Participants who stay for the taper will continue to provide urine samples, but only once a week.

NCT ID: NCT00764647 Completed - Stress Clinical Trials

Education Program for Family Caregivers

Start date: March 2006
Phase: N/A
Study type: Interventional

The purpose of this evaluation was to determine the effectiveness of an educational program designed to assist family caregivers to learn the knowledge and skills to take better care of their frail elder relatives and themselves.

NCT ID: NCT00740233 Completed - Depression Clinical Trials

Web-Based Survey of Pain, Stress and Complementary and Alternative Medicine

PROCAIM
Start date: June 2008
Phase: N/A
Study type: Observational

The investigators are inviting people with fibromyalgia, IBS, interstitial cystitis, chronic pain, and other chronic and recurring conditions to sign up and participate in a year-long Internet-based survey to study the effectiveness of alternative medicine and the interactions among stress and coping, pain, and treatment outcomes. The survey is called PROCAIM, which stands for Patient-Reported Outcomes from Complementary, Alternative, and Integrative Medicine. PROCAIM was developed under a grant to UCLA researchers from the National Center for Complementary and Alternative Medicine. This is a web-based study composed of surveys that will recur at intervals over 1 year! TO ENROLL - Log in to our web site: http://www.procaim.org/ - Register as a New User. - Select clinic name: ClinicalTrials.gov. - Read and sign the Consent Form. After participants"sign" the form with their email address, participants can begin to answer the first in a series of questionnaires. The system will send participants email reminders at the time of each scheduled follow-up for one year. For further information about PROCAIM, please contact: - Deborah Ackerman, Ph.D. - Department of Epidemiology - UCLA School of Public Health - Box 951772 - Los Angeles, CA 90095-1772 - deborah.ackerman@ucla.edu

NCT ID: NCT00740012 Completed - Type 1 Diabetes Clinical Trials

Glycemic Rises After Waking Up In Response To An Alarm Clock In Type 1-Diabetic Patients Analysed With Continuous Glucose Monitoring (GlucoDay®)

Start date: March 2007
Phase: N/A
Study type: Interventional

Study hypothesis: Waking up in response to an alarm clock may evoke a stress reaction that leads to rising glucose concentrations. The purpose of this study was to prove this hypothesis with continuous glucose monitoring over three nights. Night (a) with an alarm clock set at 2 h intervals for glucose self monitoring, Night (b) with a nurse performing blood glucose determinations, and Night (c) with the patients left undisturbed.