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Stress Disorders, Post-Traumatic clinical trials

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NCT ID: NCT03141047 Completed - Clinical trials for Symptoms of Post Traumatic Stress Disorder (PTSD)

Lifespan Integration After Sexual Trauma

Start date: March 2016
Phase: N/A
Study type: Interventional

A new psychological trauma treatment method is tested on a population (n 100) of adult women who have been sexually traumatized at one specific time 0-5 years before they enter the study.

NCT ID: NCT03129204 Completed - Depression Clinical Trials

Sensation Awareness Focused Training for Spouses

SAF-T
Start date: September 3, 2017
Phase: N/A
Study type: Interventional

The purpose of the feasibility study is prevention of Post Intensive Care Syndrome in Family (PICS-F), specifically in spouses of critically ill, mechanically ventilated patients, using a nonpharmacological intervention called Sensation Awareness Focused Training (SĀF-T). This will be accomplished using a prospective, randomized, experimental design to achieve robust and unbiased results.

NCT ID: NCT03114891 Completed - Clinical trials for Major Depressive Disorder

Accelerated TMS to a Novel Brain Target in MDD and PTSD

Start date: April 20, 2017
Phase: N/A
Study type: Interventional

This is a Clinical Trial designed to evaluate novel transcranial magnetic stimulation (TMS) methods for treating depression/PTSD. TMS is an FDA-approved procedure for treatment-resistant depression. The use of the stimulation in this current study is considered experimental. The purpose of this research study is to compare the effects of TMS at two different brain regions. This information will help the investigators to determine which treatment strategies provide the greatest clinical benefit to patients. Results of the study will provide brain and behavior measures for future work, which may be critical to developing effective disease markers and novel treatments for psychiatric conditions.

NCT ID: NCT03113175 Completed - Clinical trials for Post Traumatic Stress Disorder

Collabri Flex - Effect of Collaborative Care for People With Anxiety Disorders in General Practice

Start date: January 15, 2018
Phase: N/A
Study type: Interventional

The aim of the study Collabri Flex is to: - Develop a Danish model for collaborative care for patients with anxiety in general practice, based on past experience gained in the Collabri Project. - Examine the impact of this model compared with liaison-consultation for people with anxiety in a randomized controlled design from selected endpoints.

NCT ID: NCT03110302 Completed - Clinical trials for Posttraumatic Stress Disorder

In-Home Exposure Therapy for Veterans With Post Traumatic Stress Disorder (PTSD)

Start date: October 2012
Phase: N/A
Study type: Interventional

This study examines clinical and process outcomes following variable length prolonged exposure (PE) for posttraumatic stress disorder (PTSD) delivered by one of three treatment modalities: home-based telehealth (HBT), office-based telehealth (OBT), or in-home-in-person (IHIP).

NCT ID: NCT03103165 Completed - Depression Clinical Trials

SimCoach Evaluation: : A Virtual Human Intervention to Encourage Servicemember Help-seeking for PTSD and Depression

Start date: October 2012
Phase: N/A
Study type: Interventional

SimCoach, a computer program featuring a virtual human that speaks and gestures in a videogame-like interface, is designed to encourage servicemembers to seek help to improve their psychological health.

NCT ID: NCT03088384 Completed - Clinical trials for Stress Disorders, Post-Traumatic

Ketamine Infusion Therapy for PTSD in Combat Veterans

Start date: November 28, 2016
Phase:
Study type: Observational

Klarisana is conducting an observational study in San Antonio, Texas to see if there are tangible improvements in the symptoms of post traumatic stress disorder (PTSD) in combat veterans after receiving a series of six low-dose outpatient infusions of ketamine.

NCT ID: NCT03077919 Completed - Clinical trials for PostTraumatic Stress Disorder

Effectiveness and Acceptability of Stellate Ganglion Block for Posttraumatic Stress Disorder Symptoms - Effectiveness

Start date: May 25, 2016
Phase: N/A
Study type: Interventional

This is a multisite, randomized, blinded, sham-procedure-controlled study to evaluate the efficacy of right-sided stellate ganglion block (SGB) on the acute symptomatology of Post traumatic Stress Disorder (PTSD), evaluated by the Clinician-Administered PTSD Scale (CAPS-5) clinical interview at pre-treatment and at 8 weeks. This entry describes the effectiveness study.The acceptability study is described in a separate entry.

NCT ID: NCT03058302 Completed - Depression Clinical Trials

Study of Effectiveness and Implementation of a Mental Health Intervention With Conflict-affected Communities in Ukraine

Start date: January 2017
Phase: N/A
Study type: Interventional

This project aims to contribute to the development of a community mental health care system while directly serving the conflict affected population in east Ukraine. This project is being supported by USAID's Victims of Torture Fund. In the Spring of 2015, the Johns Hopkins University (JHU) Applied Mental Health Research Group (AMHR) was invited to make a site visit to Ukraine with USAID to make an initial assessment of current mental health problems, service capacities, and treatment need. AMHR and USAID were requested by community-based partners to provide training and support in evidence based trauma treatment for people affected by war and displacement. Extensive conflict within the borders of Ukraine is a new experience for most Ukrainians, and local psychologists and psychotherapists were not prepared for wide-spread need or trained in appropriate methods of treatment for affected populations. JHU and USAID began activities in Ukraine in June 2015 and have identified the counseling intervention, Common Elements Treatment Approach (CETA), as appropriate and relevant for this context. Community providers from the three trial sites (Kyiv, Kharkiv, and Zaporizhia) have been trained in CETA as counselors and local supervisors. An ongoing training and supervision model (Apprenticeship Model) is being implemented in the three study sites. These three sites contain significant numbers of military veterans (demobilized soldiers from the ongoing conflict) and internally displaced persons (IDPs). Adult IDPs and Veterans from the three study sites will be recruited and screened to identify those with elevated depression and/or posttraumatic stress symptoms and impaired functioning. This study will be conducted as a 3-armed randomized controlled trial. This study will test to see if both the long and a short version of CETA are effective compared to a wait-control condition.

NCT ID: NCT03056157 Completed - Clinical trials for Post-traumatic Stress Disorder

Psychosocial Rehabilitation After Moral Injury and Loss With Adaptive Disclosure

Start date: March 1, 2018
Phase: N/A
Study type: Interventional

The aim of this study is to determine the efficacy of Adaptive Disclosure for Moral Injury and Loss (AD-MIL), a combat-specific psychotherapy for war-related PTSD stemming from Moral Injury (MI) and traumatic loss (TL) with Iraq and Afghanistan War Veterans with PTSD. AD-MIL will be compared to Present Centered Therapy (PCT). AD-MIL is a modified version of Adaptive Disclosure (AD), which has been modified and extended to solely treat MI and TL by targeting psychological and behavioral obstacles to occupational, relationship, and family functioning, as well as quality of life. PCT is a manualized evidenced-based PTSD treatment used in several large-scale PTSD trials. The primary end-point is psychosocial functioning (improvements in social, educational and occupational functions and improvements in quality of life). Secondary end-points include PTSD, depression, and shame and guilt. The investigators will also explore the impact of AD-MIL on anger and aggressive behaviors, suicidal ideation, and alcohol abuse.