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Stress Disorders, Post-Traumatic clinical trials

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NCT ID: NCT00133822 Completed - Clinical trials for Post-Traumatic Stress Disorders

Civilian Post-Traumatic Stress Disorder Risperidone Clinical Trial

Start date: April 2004
Phase: Phase 1/Phase 2
Study type: Interventional

The purpose of this study is to determine whether the administration of risperidone is effective in the treatment of selective serotonin reuptake inhibitor (SSRI)-resistant post-traumatic stress disorder (PTSD) in civilians.

NCT ID: NCT00131534 Completed - Clinical trials for Posttraumatic Stress Disorders

The Trauma Recovery and Resiliency Research Project

Start date: August 1991
Phase: N/A
Study type: Observational

The overall purpose of this study is the assessment of treatment outcome among traumatized patients seeking individual and/or group therapy at the Victims of Violence Program. The study gathers information from patients using quantitative (self-report) and qualitative (interview-based) approaches, to determine changes in symptom patterns and domains of functioning relevant to psychological trauma.

NCT ID: NCT00127673 Completed - Clinical trials for Post-Traumatic Stress Disorder

Comparison of Two Treatments for Post-Traumatic Stress Disorder

Start date: September 2004
Phase: Phase 3
Study type: Interventional

This study will compare the short- and long-term effectiveness of two different treatments for people with post-traumatic stress disorder.

NCT ID: NCT00127413 Completed - Pain Clinical Trials

Integrated Treatment for Chronic Pain and Posttraumatic Stress Disorder (PTSD)

Start date: September 2004
Phase: N/A
Study type: Interventional

The purpose of this study is to examine the efficacy of an integrated treatment for Veterans with comorbid chronic pain and posttraumatic stress disorder (PTSD). It is hypothesized that Veterans who receive the integrated treatment will report more positive outcomes than individuals who are assigned to treatment as usual, pain treatment, or PTSD treatment.

NCT ID: NCT00127387 Terminated - Prostate Cancer Clinical Trials

Enbrel Versus Placebo With Radiation Therapy to Combat Fatigue and Cachexia

Start date: May 2001
Phase: Phase 2/Phase 3
Study type: Interventional

Patients who receive radiation therapy often have fatigue or a decrease in feeling well causing a "wasting" away. For patients with advanced disease of lung cancer, prostate cancer, or cancer that has spread to the bone, it is hoped that this drug may decrease this. If patients feel better during treatments they can complete the therapy without any breaks in treatment. For treatment to be most effective, it should be given in the amount needed, on a particular schedule.

NCT ID: NCT00122109 Completed - Clinical trials for Posttraumatic Stress Disorder

Telemedicine and Anger Management Groups With PTSD Veterans in the Hawaiian Islands

Start date: August 2005
Phase: N/A
Study type: Interventional

Telemedicine has the potential to profoundly influence the delivery of specialized care to the remote veteran population suffering with PTSD. Preliminary research supports telemedicine technology as a possible solution to improve access to mental health services for veterans with PTSD. The proposed research is a treatment-outcome study that will assess the clinical efficacy of conducting an Anger Management Therapy (AMT) group treatment intervention using a videoteleconferencing (VTC) modality as compared to the traditional in-person modality with veterans who have PTSD and reside in remote locations on the Hawaiian Islands. AMT is a manual-guided cognitive-behavioral, skill based group intervention that has been used nationwide in VA substance abuse programs and most recently has been adopted by many VA PTSD Clinical Teams to treat anger-related to the sequelae of PTSD.

NCT ID: NCT00121888 Completed - Clinical trials for Stress Disorders, Post-Traumatic

Trial of Paroxetine-CR for the Treatment of Patients With Post Traumatic Stress Disorder Remaining Symptomatic After Initial Exposure Therapy

Start date: December 2002
Phase: Phase 1/Phase 2
Study type: Interventional

The purpose of the study is to evaluate the effectiveness and tolerability of controlled-release paroxetine (Paxil-CR) compared to placebo (an inactive substance) for individuals who continue to have symptoms of post traumatic stress disorder (PTSD) despite receiving prolonged exposure therapy.

NCT ID: NCT00120627 Completed - Clinical trials for Stress Disorders, Post Traumatic

Mantram Repetition to Manage PTSD in Veterans

Start date: November 2005
Phase: N/A
Study type: Interventional

With ongoing war in Iraq, the incidence of posttraumatic stress disorder (PTSD) in combat veterans is increasing. Creation, implementation, and testing of new and innovative interventions are needed to provide additional options for enhancing the mental health of those with PTSD. Surveys indicate that veterans are interested in complementary approaches to health care. The purpose of this study is to determine the efficacy of the Mantram Repetition Program (MRP) delivered as a brief, 6-week, complementary and portable intervention. It includes frequent, silent repetitions of a mantram (mantra), a word or phrase with spiritual associations, to manage PTSD symptoms and improve quality of life military veterans with trauma.

NCT ID: NCT00120250 Completed - Clinical trials for Post-Traumatic Stress Disorders

Eszopiclone for Sleep Disturbance and Nightmares in Post-Traumatic Stress Disorder

Start date: June 2005
Phase: Phase 4
Study type: Interventional

The purpose of this study is to obtain data investigating the safety and efficacy of eszopiclone for the treatment of post-traumatic stress disorder (PTSD)-related sleep disturbance and the impact of improved sleep with eszopiclone treatment on neuroendocrine correlates of PTSD. The investigators hypothesize that eszopiclone will be significantly more effective than placebo and well tolerated for PTSD-related sleep disturbance, improvement in sleep will be associated with improvement in overall PTSD symptoms, and patients with PTSD-related sleep disturbances will have abnormal levels of stress hormones.

NCT ID: NCT00119028 Withdrawn - Clinical trials for Post-Traumatic Stress Disorder

Expanding and Testing VA Collaborative Care Models for Depression

ReTIDES
Start date: April 2005
Phase: N/A
Study type: Interventional

Based on the published evidence, collaborative care for depression is both necessary and sufficient for improving care and outcomes for depressed patients in primary care settings. The Translating Initiatives in Depression into Effective Solutions (TIDES) project, upon which ReTIDES is based, developed a VA-adapted version of collaborative care through input from veterans, clinicians, and managers. The initial TIDES project resulted in a clinically stable and effective model as tested in seven primary care practices in three VISNs. This positive result provided the basis for spreading and sustaining the TIDES model and initiating the study of national implementation strategies and issues.