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Stable Angina clinical trials

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NCT ID: NCT04666584 Active, not recruiting - Clinical trials for Coronary Artery Disease

Optimal Predilatation Treatment Before Implantation of a Magmaris Bioresorbable Scaffold in Coronary Artery Stenosis

OPTIMIS
Start date: December 14, 2020
Phase: N/A
Study type: Interventional

The aim of the study is to investigate if lesion preparation with a ScoreFlex balloon compared to a standard non-compliant balloon improve vascular healing and minimize lumen reduction after implantation of a Magmaris bioresorbable scaffold.

NCT ID: NCT03425305 Active, not recruiting - Heart Failure Clinical Trials

Serum Uric Acid Levels and Onset of Cardiovascular Diseases: a CALIBER Study

Start date: January 1998
Phase: N/A
Study type: Observational

Serum uric acid level is a commonly measured biomarker. The association between serum uric acid level and the risk of developing cardiovascular diseases has been observed in some studies, while others showed controversial results. Estimation of this association may help to predict cardiovascular outcomes and may guide new treatment strategies. The hypothesis is that increased serum uric acid level is associated with a range of cardiovascular diseases.

NCT ID: NCT03338309 Active, not recruiting - Unstable Angina Clinical Trials

INsTantenous wavE-Free Ratio-guided PCI Versus Fractional Flow REserve-Guided PCI in rouTine Clinical Practice, Prospective, Multicenter Registry

INTERPRET
Start date: November 1, 2017
Phase:
Study type: Observational [Patient Registry]

The current study sought to evaluate the clinical relevance of iFR-guided strategy in real world clinical practice using unrestricted study population from stable angina to acute coronary syndrome including acute ST-segment elevation myocardial infarction. Previous abundant historical data of FFR-guided strategy will be also included as historical control to validate the iFR-guided strategy.

NCT ID: NCT02892903 Active, not recruiting - Clinical trials for Acute Coronary Syndrome

In the Management of Coronary Artery Disease, Does Routine Pressure Wire Assessment at the Time of Coronary Angiography Affect Management Strategy, Hospital Costs and Outcomes?

RIPCORD 2
Start date: September 2016
Phase: N/A
Study type: Interventional

A randomised controlled trial to compare two strategies for the investigation of coronary artery disease at the time of angiography. Patients will be randomised to conventional angiography or additional, routine pressure wire assessment - measuring fractional flow reserve (FFR) - in all main vessels judged as being of sufficient vessel calibre to allow percutaneous coronary intervention (PCI) (experimental arm).

NCT ID: NCT02673424 Active, not recruiting - Stable Angina Clinical Trials

Fractional FLow Reserve And IVUS for Clinical OUtcomes in Patients With InteRmediate Stenosis

FLAVOUR
Start date: June 2016
Phase: N/A
Study type: Interventional

To compare the safety and efficacy of FFR (fractional flow reserve)-guided percutaneous coronary intervention (PCI) strategy with IVUS (intravascular ultrasound [IVUS])-guided PCI in patients with intermediate coronary stenosis.

NCT ID: NCT02468960 Active, not recruiting - Clinical trials for Coronary Artery Disease

Optimal Lesion Preparation With Non-compliant Balloons Before Implantation Of Bioresorbable Scaffolds (OPreNBiS)

Start date: March 2015
Phase: N/A
Study type: Interventional

Study aim : To compare a novel strategy of lesion preparation with noncompliant balloons before implantation of BVS (Bioresorbable Vascular Scaffold). Hypothesis: Predilatation with non-compliant balloons could facilitate optimal deployment of BVS. By achieving good scaffold apposition a need for post-dilatation could be significantly reduced. This is expected to result in better short- and long-term outcomes.

NCT ID: NCT02352402 Active, not recruiting - Clinical trials for Coronary Artery Disease

The Effect Of Ticagrelor On Saphenous Vein Graft Patency In Patients Undergoing Coronary Artery Bypass Grafting Surgery

POPular CABG
Start date: March 2015
Phase: Phase 3
Study type: Interventional

In the POPular CABG study we investigate if the addition of ticagrelor, a drug that inhibits blood platelets from clotting, to treatment with aspirin will reduce the rate of saphenous vein graft occlusion as assessed with coronary computed tomography angiography at 1 year after coronary artery bypass grafting surgery.

NCT ID: NCT02244853 Active, not recruiting - Stroke Clinical Trials

Heart Rate and Cardiovascular Diseases Prognosis in People With Stable Coronary Artery Disease

Start date: September 2013
Phase: N/A
Study type: Observational

The Cardiovascular disease research using Linked Bespoke studies and Electronic Records (CALIBER) e-health database was the data resource for this study. CALIBER links patient records from four different data sources: Clinical Practice Research Database (CPRD), MINAP (Myocardial Ischaemia National Audit Project registry) Hospital Episodes Statistics (HES), the Office for National Statistics (ONS).

NCT ID: NCT02131142 Active, not recruiting - Clinical trials for Ischemic Heart Disease

BioFreedom US IDE Feasibility Trial

Start date: August 2014
Phase: Phase 2/Phase 3
Study type: Interventional

The purpose of this study is to collect additional safety and effectiveness data for on the Biosensors BioFreedomâ„¢ BA9 Drug Coated Coronary Stent in patients with native, de novo coronary artery disease.

NCT ID: NCT01918150 Active, not recruiting - Clinical trials for Acute Coronary Syndrome

Comparative Phase IV Study: Efficacy And Safety of TiTAN2 Versus COBALT-CHROME Stents- EVIDENCEII

EVIDENCE II
Start date: March 2011
Phase: Phase 4
Study type: Interventional

The purpose of this study is to compare the effectiveness and safety, at 24 months, of the TITAN2 stent to any bare-metal stent (BMS) in Cobalt-Chromium in a population presenting an indication for these stents among 40% of which present an acute coronary syndrome (ACS).