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Sleep Quality clinical trials

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NCT ID: NCT05950646 Recruiting - Dexmedetomidine Clinical Trials

Mini-dose Dexmedetomidine-Esketamine Infusion and Perioperative Sleep Quality

Start date: November 1, 2023
Phase: Phase 4
Study type: Interventional

Sleep disturbances are prevalent in older patients with osteoarthrosis or fracture who are scheduled for knee or hip replacement surgery. The occurrence of sleep disturbances is associated with worse outcomes including increased risk of delirium and cardiac events, and worsened functional recovery. Dexmedetomidine is a highly selective α2-adrenergic agonist with sedative, anxiolytic, and analgesic properties. It exerts sedative effects via activating the endogenous sleep pathways and produces a state like non-rapid eye movement sleep, which is different from opioid- and benzodiazepine-induced sedation. Esketamine is a N-methyl-D-aspartic acid receptor antagonist and has been used as an anesthetic and analgesic. Recent studies showed that low-dose esketamine has anti-depressive and sleep-promoting effects. The investigators suppose that mini-dose dexmedetomidine-esketamine combined infusion at night can improve perioperative sleep quality in patients scheduled for knee or hip replacement surgery.

NCT ID: NCT05876650 Completed - Pain Clinical Trials

Pilates Exercises v/s Yoga on Rounded Shoulders

Start date: December 1, 2022
Phase: N/A
Study type: Interventional

To Compare the effects of Pilates exercises an yoga on rounded shoulders

NCT ID: NCT05869721 Recruiting - Mood Clinical Trials

Effects of Yoga on Women With Breast Cancer

Start date: May 4, 2023
Phase: N/A
Study type: Interventional

Upper limb complications and sleep disturbances are prevalent, persistent, and serious health problems in women with breast cancer. However, these problems are underrecognized in clinical practice and thus have substantial adverse impacts on the health and quality of life of women with breast cancer. As yoga practices have been shown to improve physical and psychological health in people with cancer, such practices may also alleviate upper limb complications and sleep disturbances in women with breast cancer. However, there are few evidence-based guidelines or protocols to support the integration of yoga therapy into clinical practice for managing the health conditions of women with breast cancer. Therefore, this study aims to investigate the effects of yoga therapy on improving the upper limb functions, sleep quality, and quality of life in women with breast cancer.

NCT ID: NCT05811429 Completed - Depression Clinical Trials

Comparison of Aerobics and Pilates Exercises in Primigraivda Females

Start date: November 20, 2022
Phase: N/A
Study type: Interventional

Many physical changes, as well as emotional disturbance, occur during pregnancy. In addition to external physical changes, some mental health problems such as depression, sleep and psychosis significantly increase during pregnancy. Aerobic exercises during pregnancy in primigravida females has a positive effect on depression and sleep as a primary and secondary preventive strategy. The study will be a randomized clinical trial and Setting will be children hospital and Mehmooda hospital sheikhupura. This study will be completed in ten months and convenient sampling technique will be used. Fourty two subjects will be assigned randomly by using lottery method into two groups. Group A will receive Aerobic exercises and Group B will receive Pilate exercises. Warm up (walking) and cool down period of ten minutes will be performed by both groups. Data will be collected from all participants at baseline and after 8 weeks of treatment by using CES-D and PSQI questionnaire. After assessing the data will be analyzed by using parametric or non-parametric test by using SPSS-25.

NCT ID: NCT05749939 Active, not recruiting - Quality of Life Clinical Trials

Acceptance Commitment Therapy for Caregivers of People With Memory Loss

Start date: February 16, 2023
Phase: Phase 3
Study type: Interventional

Family caregivers for persons with dementia report high levels of depression, stress, and burden. Caregivers' limited time, transportation constraints, and unpredictable schedules make on-line, self-guided interventions more accessible and scalable. Acceptance and Commitment Therapy (ACT) is an established and effective in-person therapy, well-suited to the dementia care giving context where caregivers cannot minimize stress exposure, and report difficult thoughts and emotions. ACT for Caregivers is an on-line self-guided ACT intervention that showed effectiveness in a Stage I pilot (n=52) with participants reporting decreased depressive symptoms, stressful reactions to caring, and caregiver burden, and increased quality of life and positive aspects of caring (all p <.05). Learning from the pilot, the current Stage III intervention will shorten the program from 10 sessions to 6 sessions. The investigators introduce a wait list randomized control trial (RCT) design with fully longitudinal mixed methods to evaluate ACT for Caregivers. Data will be collected at pretest, post-test, and 6-weeks follow-up. Study aims are: 1) to evaluate ACT for Caregivers in a larger sample using an RCT, 2) to understand user experiences and the process of change by collecting short response data from all participants at all time points and interviewing a subset of participants in-depth at two time points, 3) to integrate quantitative and qualitative findings and examine areas of convergence and divergence. This project offers a promising prevention and intervention program to support family caregivers that is scalable, at low cost and with high impact.

NCT ID: NCT05742776 Recruiting - Clinical trials for Carpal Tunnel Syndrome

The Relationship Between Ultrasonographic Findings and Sleep Quality in Carpal Tunnel Syndrome

Start date: February 23, 2023
Phase:
Study type: Observational

The aim of our study is to determine the relationship between disease severity and sleep quality in CTS patients and to compare the findings with healthy controls.

NCT ID: NCT05732064 Recruiting - Breast Cancer Clinical Trials

Dexmedetomidine-esketamine Combined Nasal Administration and Perioperative Sleep Quality

Start date: May 22, 2023
Phase: Phase 4
Study type: Interventional

Breast cancer patients often have sleep disturbances during the perioperative period. Dexmedetomidine is a highly selective alpha 2-adrenoceptor agonist with sedative, anxiolytic, and analgesic effects. Previous studies showed that night-time low-dose dexmedetomidine infusion improved sleep quality. Esketamine is a N-methyl-D-aspartic acid receptor antagonist and has been used as an anesthetic and analgesic. Recent studies showed that low-dose esketamine has anti-depressive and sleep-promoting effects. The investigators suppose that low-dose dexmedetomidine-esketamine combined nasal administration at night can improve perioperative sleep quality in patients scheduled for breast cancer surgery.

NCT ID: NCT05726162 Recruiting - Sleep Quality Clinical Trials

Effects of Biofeedback-based Music Program Using a Smart Device Application on Perioperative Sleep Quality

Start date: August 21, 2023
Phase: N/A
Study type: Interventional

The purpose of this study is to investigate whether the effects of biofeedback-based music programs using a smart device application can improve perioperative sleep quality in patients undergoing breast cancer surgery.

NCT ID: NCT05718024 Recruiting - Clinical trials for Mechanical Ventilation

Night-time Dexmedetomidine-esketamine Infusion and Sleep Quality With Mechanical Ventilation

Start date: November 1, 2023
Phase: Phase 4
Study type: Interventional

Dexmedetomidine and ketamine are both suggested for sedation and analgesia in ICU patients with mechanical ventilation. Recent studies suggest that low-dose dexmedetomidine or ketamine/esketamine may improve sleep quality of ICU patients. The purpose of this trial is to observe whether night-time infusion of low-dose dexmedetomidine-esketamine combination can improve sleep structure of patients with mechanical ventilation in the ICU.

NCT ID: NCT05716373 Completed - Pain Clinical Trials

The Effect of Reiki Application on Pain, Fatigue and Sleep Quality in Elderly Persons Staying in Nursing Homes

Start date: December 1, 2022
Phase: N/A
Study type: Interventional

A person's life is a stage that passes in the time interval that ends with his birth when he opens his eyes to the world and his death when he closes his eyes to the world. Old age is a forced end for all people. Sleep is one of the most important and basic human needs. It prepares the individual for a new day by resting the body, strengthening and regulating the cerebral functions and repairing the brain. While a change in sleep pattern and quality affects a person's daily life activities, long-term persistence of this change may lead to deterioration of body and mental health.During Reiki practices, the hands are held in each position for 3-5 minutes by touching the head, neck, chest, abdominal cavity and groin. In problem areas, this time can be extended to 10-20 minutes. The duration of treatment lasts an average of 30-90 minutes. During the application, the person is in a lying or lying position and does not need to take off his clothes.