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Dexmedetomidine clinical trials

View clinical trials related to Dexmedetomidine.

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NCT ID: NCT06331182 Not yet recruiting - Dexmedetomidine Clinical Trials

Dexmedetomidine and Ketamine as an Adjuvant in External Oblique Intercostal Plane Block for Post Thoracotomy Pain

Start date: March 30, 2024
Phase: N/A
Study type: Interventional

The aim of this study is to compare the role of dexmedetomidine and ketamine as an adjuvant in external oblique intercostal plane block for post thoracotomy pain.

NCT ID: NCT06327399 Recruiting - Dexmedetomidine Clinical Trials

Dexmedetomidine Infusion Dose Versus Rapid Bolus Dose Before Tracheal Intubation.

Start date: January 21, 2024
Phase: Phase 2
Study type: Interventional

Dexmedetomidine bolus dose may provide similar or less hemodynamic changes (less bradycardia and less hypertension) than infusion dose during induction of anaesthesia and tracheal intubation.

NCT ID: NCT06231979 Not yet recruiting - Dexmedetomidine Clinical Trials

Adding Dexmedetomidine to Bupivacaine for Bilateral Erector Spinae Block

Start date: February 25, 2024
Phase: Phase 4
Study type: Interventional

The aim of this study is to compare the analgesic effect of bilateral US-guided ESPB using bupivacaine alone versus bupivacaine and DEX in lumbar fusion surgeries.

NCT ID: NCT06229054 Recruiting - Dexmedetomidine Clinical Trials

Dexmedetomidine in Obturator Nerve Block as an Analgesic in Transurethral Surgeries

Start date: February 1, 2024
Phase: Early Phase 1
Study type: Interventional

in our study, we will investigate the impact of adding dexmedetomidine to bupivacaine for the potency of the obturator nerve block and prevention of the postoperative pain associated with transurethral surgery in comparison of obturator nerve block with bupivacaine alone

NCT ID: NCT06210061 Recruiting - Dexmedetomidine Clinical Trials

Propofol-Fentanyl-Dexmedetomidine and Propofol-Fentanyl-Sevoflurane Anesthesia for Major Spine Surgery Under Somato Sensory- and Motor- Evoked Potential Monitoring

Start date: September 1, 2023
Phase: N/A
Study type: Interventional

The objective of this study is to evaluate the effect of adding dexmedetomidine on evoked potentials in adult patients undergoing spinal surgery under intravenous anesthesia

NCT ID: NCT06207331 Recruiting - Clinical trials for Chronic Obstructive Pulmonary Disease

Effects of Atomized Dexmedetomidine on Lung Function in Patients With Chronic Obstructive Pulmonary Disease

Start date: October 28, 2023
Phase: N/A
Study type: Interventional

Studies have shown that intravenous infusion and nebulized dexmedetomidine can improve lung function in mechanically ventilated patients, including those with preoperative COPD, exerting lung protection. However, these studies are based on mechanical ventilation patients under general anesthesia, and more intuitive research is needed on whether dexmedetomidine can also exercise pulmonary precaution in awake patients. Pulmonary function monitoring is the most direct way to evaluate changes in lung function in awake patients. Portable pulmonary function machines can assess lung function in a variety of settings. In addition, compared with intravenous administration, nebulized inhalation administration directly acts on the mucosa of the respiratory tract, does not involve invasive operations, and has higher safety and comfort. Therefore, this study intends to use portable pulmonary function instruments and non-invasive ambulatory respiratory monitors to evaluate the effect of nebulized dexmedetomidine on lung function in COPD patients to guide the perioperative management of COPD patients.

NCT ID: NCT06138340 Recruiting - Clinical trials for Postoperative Delirium

The Effects of Anesthetics on Brain Network Connectivity in Patients With Supratentorial Glioma

Start date: August 31, 2023
Phase:
Study type: Observational

Perioperative anesthesia can affect postoperative cognitive function. In our previous study, intraoperative dexmedetomidine (Dex) infusion reduced the incidence of delirium within the first 5 days after brain tumor. However, the mechanism is still unclear. With the development of neuroimaging, multimodal neuroimaging technology provide a new method to explore the underlying mechanism. Therefore, the purpose of this study is to analyze the alterations of brain network under sedation and anesthesia by different anesthetics in patients with supratentorial glioma and their association with cognition.

NCT ID: NCT06133712 Recruiting - Dexmedetomidine Clinical Trials

Dexmedetomidine, Ozone and Dexamethasone Local Injection in Carpal Tunnel Syndrome for Pain Relief

Start date: November 1, 2023
Phase: N/A
Study type: Interventional

The aim of the present study is to compare the analgesic efficacy of Dexmedetomidine, Ozone and Dexamethasone regional injection in carpal tunnel syndrome.

NCT ID: NCT06125665 Recruiting - Clinical trials for Chronic Obstructive Pulmonary Disease

Aminophylline on Perioperative Lung Mechanics in COPD Morbidly Obese Patients Undergoing Laparoscopic Bariatric Surgery

Start date: November 11, 2023
Phase: N/A
Study type: Interventional

The aim of this study is to evaluate the usefulness of adding aminophylline to dexmedetomidine intravenous infusion intraoperatively on oxygenation and lung mechanics in chronic obstructive pulmonary disease (COPD) morbidly obese patients undergoing bariatric surgery.

NCT ID: NCT06098209 Recruiting - Stress Clinical Trials

Dexmedetomidine and Propofol in Mechanically Ventilated Patients by Using Salivary Alpha-amylase as a Stress Marker

Start date: October 24, 2023
Phase: N/A
Study type: Interventional

The aim of this study is to compare the efficacy of dexmedetomidine and propofol on decreasing stress in mechanically ventilated patients by using salivary alpha-amylase as a stress marker.