Evaluation of a Low-threshold Exercise And Protein Supplementation Intervention for Women (LEAP-W) Experiencing Homelessness and Addiction: Protocol for a Single Site Intervention Study.
Background: Frailty is a complex multi-dimensional state of increased vulnerability to adverse health outcomes and is usually associated with older age but there is growing evidence of accelerated ageing and frailty in non-geriatric populations, including those experiencing socio-economic deprivation and extreme social exclusion, such as people experiencing homelessness. Addiction, as a coping mechanism for prior trauma, is common among people who are homeless and can have a gendered dimension. Women experiencing homelessness and addiction have unique needs which require a gendered approach. The aim of this study is to explore the effectiveness of an exercise intervention to target the known physical functioning deficits and frailty which this population experiences. Methods: This mixed-methods study will explore physical functioning deficits and frailty in women experiencing homelessness and addiction, using a bespoke test battery and an exercise intervention. Physical function (10m Walk Test, 2 Minute Walk Test, Single Leg Stance Test, Chair Stand Test, hand grip dynamometry), frailty (Clinical Frailty Scale and the SHARE-FI) and nutritional status (Mini-Nutritional Status), pain (Numerical Pain Rating Scale) and quality of life (SF 12-V2) will be evaluated. The intervention will involve a 3-times weekly exercise programme with protein supplementation for 10 weeks. Following this, qualitative interviews, which will be thematically analysed using Braun & Clarke methodology, will be conducted. This study will be conducted in Dublin from February to July 2024. Discussion: Little is kn own about frailty-focussed interventions in women experiencing homelessness and addiction. This proposed study will help to increase the knowledge base regarding the physical health burden and frailty experienced by this extremely vulnerable population and will deliver a targeted intervention with a gendered dimension to mitigate its affects. The findings of this research will help narrow this research gap and will guide clinicians and policy makers to implement unique gender-based treatment strategies for this population.
NCT06264895 — Chronic Disease
Status: Active, not recruiting
http://inclinicaltrials.com/chronic-disease/NCT06264895/
A Web-based Survey -Relationship Between Smartphone Addiction and Temporomandibular Joint Disorders Among Adults in Egypt: Cross Sectional Study
Cross sectional study to investigate the relation between Smartphone addiction and temporomandibular disorders among youth population in Egypt. An online- based questionnaire study. A 296 participants who are Egyptians with age between18 and 35 years old without prior neck and upper extremity related diseases, orofacial trauma or surgeries, history of rheumatoid arthritis or congenital musculoskeletal problems. An online- based questionnaire will be sent through different social media platforms, it will include three screens, the first includes the consent form, the second includes the demographic data (year of birth, current educational status, gender and geographic information ), and the third page includes questionnaires .
NCT06261697 — Temporomandibular Disorders
Status: Not yet recruiting
http://inclinicaltrials.com/temporomandibular-disorders/NCT06261697/
Noninvasive Targeted Neuromodulation for Treatment of Food Addiction
This study will evaluate a new form of non-invasive deep brain therapy for food addiction. Low-intensity transcranial focused ultrasound stimulation will first be delivered using a range of stimulation parameters during psychophysical and physiological monitoring. A well-tolerated stimulation protocol will be selected for subsequent testing in a blinded randomized sham-controlled trial. The trial will evaluate brain target engagement using magnetic resonance imaging, Food Cravings Questionnaire-State, and changes in subject's weight over the course of the study.
NCT06249711 — Obesity
Status: Recruiting
http://inclinicaltrials.com/obesity/NCT06249711/
The Application of Repetitive Transcranial Magnetic Stimulation (rTMS) as an Adjunct Therapy in Reduction of Craving and Consumption of Illicit Drugs
This study also aims to develop and apply a standard repetitive transcranial magnetic stimulation (rTMS) protocol on drug users. The investigators want to focus on the effects of rTMS on amphetamine and cocaine as they are the most commonly used types of illicit drugs in Hong Kong. The primary research question is: • To examine if rTMS can reduce craving and consumption of the most commonly used illicit drugs (amphetamine, cocaine) among people with drug use disorders in Hong Kong? The secondary research questions are: - What is the association between rTMS protocol (frequency, intensity) and drug craving and consumption? - Would there be gains in executing functioning among participants who have received rTMS treatment? - Would there be a reduction in depressive and anxiety symptoms among participants who have received rTMS treatment? The investigators would use a cross-over design (figure 1) to investigate the effects of rTMS. The investigators would recruit participants through community drug rehabilitation and youth outreach services. Participants who meet the selection and exclusion criteria will be invited to join. Upon obtaining their written consent, the investigators would randomize participants to a treatment (rTMS) group and a sham stimulation (placebo) group. Upon completing the first phase (2 weeks), there would be a washout period of 2 weeks. The two groups will swap (treatment becomes sham, and vice-versa) and the second phase will proceed. A double-blinded procedure will be implemented. Outcome measures will be conducted at baseline, after Phase I, at the start of Phase II, and at the end of Phase II.
NCT06244329 — Substance Use Disorders
Status: Completed
http://inclinicaltrials.com/substance-use-disorders/NCT06244329/
Motivational Interviewing Supported Health Education on Digital Game Addiction and Cyberbullying in Adolescents Impact on Behavior
With the widespread use of technology and internet, digital game addiction and cyberbullying behaviors have increased among adolescents. Effective interventions are needed to prevent these behaviors. The aim of the study is to determine the effect of health education supported by motivational interviewing on digital game addiction and cyberbullying behaviors in adolescents. The research will be conducted with a randomized controlled trial design. The intervention group will receive six sessions of motivational interviewing-supported health education. Within the scope of the intervention, the first two sessions will be health education and the last four sessions will be motivational interviewing. It is planned that each session will be 35 minutes and the sessions will be implemented one week apart.
NCT06241989 — Level of Cyberbullying
Status: Not yet recruiting
http://inclinicaltrials.com/level-of-cyberbullying/NCT06241989/
Effects of Fibromyalgia Education on Smart Phone Addiction, Pain, and Quality of Life in Fibromyalgia Patients: A Randomized Controlled Study
The study focuses on fibromyalgia, a condition characterized by chronic pain, fatigue, and associated issues like sleep disorders, depression, and anxiety. The investigators' goal is to detect smart phone addiction among fibromyalgia patients and assess potential improvements in their quality of life and smart phone addiction after receiving fibromyalgia education. Participants will report their recent exercise, social activities, sleep quality, and screen time for the past week. They will also complete the Revised Fibromyalgia Impact Questionnaire (FIQR) to measure pain and physical function and the Smart Phone Addiction Scale-Short Version (SAS-SV) to assess smart phone use. Diaries will track daily exercise, socialization, sleep, and screen time for 20 days. The intervention group will receive fibromyalgia education, covering an overview of fibromyalgia, coping strategies, and discussions on the impact of digital addictions. This education, delivered via a brief Microsoft PowerPoint program presentation by a physician, aims to help patients. After 20 days, all participants will redo the FIQR and SAS-SV assessments, and diary data will be collected. This study examines how physician-provided fibromyalgia education affects pain levels, quality of life, smart phone addiction, socialization, exercise, sleep, and screen time based on patient diaries. The results will deepen our understanding of how brief education can enhance the lives of fibromyalgia patients and aid in developing more effective strategies to manage pain and improve their quality of life.
NCT06239779 — Quality of Life
Status: Recruiting
http://inclinicaltrials.com/quality-of-life/NCT06239779/
Addictions and Attention Deficit Disorder With or Without Hyperactivity
The ADA cohort aims for the systematic and standardized collection of sociodemographic, clinical and neuropsychological data, during 2 visits (inclusion and 12 months), from patients suffering from the co-occurrence of ADHD (Attention Deficit Hyperactivity Disorder) and addiction(s), in addition to the treatment as usual adapted to each situation.
NCT06232226 — Attention Deficit Hyperactivity Disorder
Status: Not yet recruiting
http://inclinicaltrials.com/attention-deficit-hyperactivity-disorder/NCT06232226/
Cannabidiol in the Treatment of Opioid Use Disorder
The long-term goal of the project is to determine whether cannabidiol (CBD) can reduce craving and relapse in individuals with opioid use disorder (OUD). The first phase of our project was an open cross-over design study in healthy individuals to confirm the safety and pharmacokinetic (PK) effects of CBD. This next phase is to determine whether CBD can serve as a potential adjunct treatment to reduce craving and anxiety in individuals with OUD maintained on opioid agonist therapy.
NCT06206291 — Opioid Use Disorder
Status: Recruiting
http://inclinicaltrials.com/opioid-use-disorder/NCT06206291/
Prevalence of Internet Addiction and it's Effects on Psychological Well-being of Adults in Hong Kong
The goal of this quantitative study is to learn about the the prevalence of internet addiction and its effects on psychological well-being of adults in Hong Kong. The main question it aims to answer is: • What is the prevalence of internet addiction and its effects on psychological well-being of adults in Hong Kong Participants will be invited to complete a set of questionnaire that includes assessment on their level of Internet use, depression, anxiety, sleep quality, QOL together with basic demographic data in the current situation of COVID with popularity of Metaverse..
NCT06205004 — Internet Addiction
Status: Recruiting
http://inclinicaltrials.com/internet-addiction/NCT06205004/
Cognitive Behavior Therapy for Social Media Addiction, Insomnia, and Family Relationship Among Individuals With Social Media Addiction: A Randomized Control Tria
Objectives This study is designed to investigate the following objectives To manage the social media addiction in order to improve lifestyle, attitude and family relations of the individuals and explore related psychological problems which can arise because of this addiction. To explore the effectiveness of cognitive behaviour therapy (CBT) in the management of social media addiction in individuals which is decreasing the health of their lifestyle, attitude and family bonding. To explain how abusive use of social media can increase the risk of psychological and behavioural problems.
NCT06189534 — Cognitive Behavior Therapy for Social Media Addiction
Status: Active, not recruiting
http://inclinicaltrials.com/cognitive-behavior-therapy-for-social-media-addiction/NCT06189534/