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Clinical Trial Details — Status: Completed

Administrative data

NCT number NCT03820362
Other study ID # FPU15/01721
Secondary ID
Status Completed
Phase
First received
Last updated
Start date February 2016
Est. completion date November 2018

Study information

Verified date January 2019
Source University of Barcelona
Contact n/a
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

Personal identity is being recently recognized as a core element for mental health disorders, with relevant clinical implications. However, scarcity of data exists on its role in schizophrenia and related disorders. The repertory grid (RGT), a technique derived from personal construct theory, has been used in different clinical and non-clinical contexts for the study of the construction perception of self and others, to appreciate aspects of interpersonal construing such as polarization and differentiation (unidimensional thinking) or self-construction.and Our study aims to explore the potential influence of the structure of personal identity and of other relevant cognitive factors (social cognition, metacognition, neurocognition) in positive and negative symptoms in people suffering schizophrenia and related disorders.


Description:

Over recent years, the importance of the sense of self and personal identity in psychopathology and its treatment has been highlighted. Several studies inspired in the Personal Construct Psychology framework have found a variety of identity characteristics in clinical conditions such as depression or eating disorders, but the evidence in schizophrenia and other psychotic related disorders is scarce.

In addition, current psychological models of positive and negative symptoms highlight the influence of neurocognition, social cognition and self-concepts in the development and maintenance of psychotic experiences. Despite the recognized need of person-centered approaches to understand psychopathology processes in psychosis, psychological models for explaining psychotic symptoms have not explored sufficiently the role of this kind of person-centered measures.

Aim

1. To examine the influence of the structure of personal identity and other relevant cognitive factors in positive and negative symptoms

Hypotheses

1. Positive symptoms will be influenced by dichotomous thinking style and construction of self as measured with the RGT.

2. Negative symptoms will be affected by the richness of the construct system as measured with the RGT.


Recruitment information / eligibility

Status Completed
Enrollment 85
Est. completion date November 2018
Est. primary completion date November 2018
Accepts healthy volunteers No
Gender All
Age group 18 Years to 60 Years
Eligibility Inclusion Criteria:

- diagnosis of schizophrenia, psychotic disorder not otherwise specified, delusional disorder, schizoaffective disorder, brief psychotic disorder, or schizophreniform disorder

- age between 18 and 60 years.

- patients from outpatient mental health units

Exclusion Criteria:

- traumatic brain injury, dementia, or intellectual disability (pre-morbid IQ <70)

- current substance dependence

Study Design


Related Conditions & MeSH terms


Locations

Country Name City State
Spain Parc Sanitary Sant Joan de Déu Sant Boi De Llobregat Barcelona

Sponsors (4)

Lead Sponsor Collaborator
University of Barcelona Agència de Gestió d'Ajuts Universitaris i de Recerca, Catalunya, Spain, Ministerio de Educación y Formación Profesional, Spain, Parc Sanitari Sant Joan de Déu

Country where clinical trial is conducted

Spain, 

Outcome

Type Measure Description Time frame Safety issue
Primary Self-ideal discrepancy, RGT Self-esteem. Possible range: 0-0,60. Higher values represent a worse outcome 2 hours
Primary Self-others discrepancy, RGT Perceived social isolation. Possible range: 0-0,60. Higher values represent a worse outcome 2 hours
Primary Interpersonal construct differentiation, RGT Percentage of Variance Accounted for the First Factor. Possible range: 0-100. Higher values represent a worse outcome 2 hours
Primary Polarization, RGT Dichotomous thinking style in the interpersonal context. Possible range: 0-100. Higher values represent a worse outcome 2 hours
Primary Number of elicited constructs, RGT Quantity of constructs that the person is able to express to describe self and others. Possible range: 10-50. Higher values represent a better outcome 2 hours
Primary Psychotic symptoms (PANSS, Kay et al. 1987; Peralta & Cuesta, 1994). Positive and negative symptoms of psychosis. Range: 7-112. Higher values represent a worse outcome. 40 minutes
Primary Metacognition: BCIS (Beck et al. 2004; Gutiérrez-Zotes et al. 2012); Garety et al, 1991; Dudley et al, 1997) Cognitive insight. Range: 0-45. Higher values represent a better outcome 15 minutes
Primary Theory of mind: the Hinting Task (Corcoran et al., 1995; Gil-Sanz et al., 2012) Possible range: 0-12. Higher values represent a better outcome 5 minutes
Primary General intellectual functioning (WAIS) vocabulary subscale. Range: 70-140. Higher values represent a better outcome 20 minutes
Primary Executive functioning: WSCT (Bergs et al., 1948) Wisconsin Card Sorting Test. Categories completed and perseverative errors. Higher values represent a better outcome 15 minutes
Secondary Sociodemographical data Gender, chronicity, antipsychotic dosage, diagnosis, age, marital status, education level, employment situation 10 minutes
Secondary Depressive symptoms Beck Depression Inventory (Beck et al. 1996; Sanz, Perdigón & Vázquez, 2003). Range_ 0-63. High values represent a worse outcome. 10 minutes
Secondary General functioning Global Assessment of Functioning (Endicot et al., 1976). Range: 0-100. Higher values represent a better outcome. 5 minutes
Secondary Self-esteem Rosenberg self-esteem scale (Martín Albó et al., 2007). Range: 0-40. Higher values represent a better outcome 5 minutes
Secondary Social functioning Social Functioning Scale (Birchwood et al., 1990; Torres & Olivares, 2000). Range: Range: 45-195 20 minutes
Secondary Psychological distress CORE-OM (Evans et al., 2002; Trujillo et al., 2016). Range: 0-4. Higher values represent a worse outcome 10 minutes
Secondary Jumping to Conclusions The beads task (Garety et al., 1991; Dudley et al, 1997). Dichotomous: yes/no. A "yes" represents a worse outcome 15 minutes
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